Michael C. Oldham, PhD studies the organization of the transcriptome in the developing and adult human brain, and how this organization differs among primate species and brains affected by disease.
Samuel Pleasure, MD, PhD studies the development of the brain, in particular the mechanisms regulating cell proliferation, migration and axon guidance during prenatal development.
Jennifer Puck, MD studies how lymphocytes differentiate from hematopoietic stem cells; she conducts basic research on the genetics of severe combined immunodeficiency (SCID) and uses lentivirus based gene therapy to conduct clinical trials treating patients with X-linked SCID and Artemis deficient SCID.
Jeremy Reiter, MD, PhD focuses on identifying novel intercellular signals that direct the differentiation of embryonic stem cells along defined lineages.
John Rubenstein, MD, PhD explores the origin of inhibitory interneurons in the brain and their possible utility in cell-based therapy for brain disorders such as epilepsy and Parkinson’s disease.
Bjoern Schwer, MD, PhD is investigating molecular processes that affect genomic stability in developing and mature neural lineage cells, and the role of these processes in development, aging and cancers of the brain.
