Mission Bay

Kevin Shannon, MD

Professor

Kevin Shannon, MD studies signaling mechanisms that regulate the growth and differentiation of normal and leukemic stem cells. He is particularly interested in the genetic and biochemical basis of inherited leukemia predispositions and the regulation of hematopoietic stem cell and progenitor cell growth by Ras signaling.

Dean Sheppard, MD

Professor

Dean Sheppard, MD, PhD studies the role of integrins and signaling mechanisms in cell and tissue interactions in the lung, specifically in lung injury and fibrosis.

Deepak Srivastava, MD

Professor
Pediatrics

Our laboratory focuses on understanding the causes of heart disease and on using knowledge of cardiac developmental pathways to devise novel therapeutic approaches for human cardiac disorders. Specifically, we study the molecular events regulating early and late developmental decisions that instruct progenitor cells to adopt a cardiac cell fate and subsequently fashion a functioning heart. We focus on transcriptional and post-transcriptional steps, including those involving microRNAs.

Hua Su, MD

Professor
Anesthesia

Hua Su, MD studies gene and cell based therapies for cerebral vascular diseases, including stroke.

Saul Villeda, PhD

Associate Professor
Anatomy

Saul Villeda, PhD studies how molecular immune-related changes in old blood impair stem cell function and cognitive processes in the brain during aging, and conversely how young blood can reverse these impairments.

William A. Weiss, MD, PhD

Professor

William Weiss, MD, PhD is interested in developing and characterizing mouse models that faithfully recapitulate the biology and genetics of human tumors of the nervous system.

Keith Yamamoto, PhD

Emeritus Professor
Cellular Molecular Pharmacology

Keith Yamamoto, PhD is interested in mechanisms by which gene transcription is regulated in different cell types and physiological or pathological settings. He studies the activity of the intracellular receptors, including receptors for glucocorticoids, androgens and thyroid hormone in signal transduction and transcriptional control.

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