The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research is one of the largest and most comprehensive programs of its kind in the United States.

In more than 140 labs across UCSF, scientists are carrying out studies in cell culture and animals with the goal of understanding and developing treatment strategies for such conditions as heart disease, diabetes, epilepsy, multiple sclerosis, Parkinson’s disease, Lou Gehrig’s disease, spinal cord injury and cancer.

The Broad Center is structured around eight research pipelines aimed at driving discoveries from the lab bench to the patient. Each pipeline focuses on a different organ system, including the blood, pancreas, liver, heart, reproductive organs, nervous system, musculoskeletal tissues, skin and eyes. Each of these pipelines is overseen by two leaders of international standing – one representing the basic sciences and one representing clinical research. This approach has proven successful in the private sector for driving the development of new therapies.

Like all of UCSF, the Center fosters a highly collaborative culture, encouraging the cross-pollination of ideas between scientists of different disciplines and years of experience. Researchers studying pancreatic beta cells damaged in diabetes collaborate with those studying nervous system diseases, because at the heart of their research are stem cells that undergo similar molecular signaling on the way to becoming both cell types. The opportunity to work in this culture has drawn some of the country’s premier scientists to the center.

UCSF Mourns the Loss of Eli Broad (1933-2021) 

The UC San Francisco community is deeply saddened to learn of the passing of Eli Broad, a renowned entrepreneur and philanthropist whose generosity supported scientific and medical research, the arts, and high-quality educational opportunities for students across the U.S. 

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF will be forever grateful to Mr. Broad for his extraordinary vision and generosity. His investments in UCSF’s stem cell endeavors have enabled our scientists to accelerate our research, by bringing some of the world’s leading stem cell scientists together under one roof and providing them with a setting that promotes collaboration and an exchange of ideas, both key to making clinical advances to improve human health. His legacy will live on through the breakthroughs and improvements in patient care made possible by his support of our work.  

In fact, Mr. Broad’s impact on stem cell science at UCSF and beyond will be felt for generations to come. Along with his wife of over 60 years, Edye, Mr. Broad supported stem cell research at a time when the country most needed national leadership in this area of scientific inquiry. Eager to leverage his philanthropic dollars for maximum impact, Mr. Broad saw an opportunity to fund stem cell research when Californians passed a proposition funding $3 billion in bonds to support stem cell research and research facilities in 2004. Shortly after President George W. Bush vetoed a bill that would have supported federal funding of stem cell research, the couple’s philanthropic organization, The Eli and Edythe Broad Foundation, made an initial investment of $65 million to create three new Broad Stem Cell Centers at UCSF, UCLA, and the University of Southern California. The Foundation has since made supplemental gifts bringing their total contribution to these centers to $113 million. The efforts have made California a leading center of stem cell research in the country. 

To learn more about the remarkable life of Eli Broad, please visit this link

In Memoriam: Katja Brueckner, PhD

In Memoriam: Zena Werb, MD, PhD