People

Bjoern Schwer, MD, PhD

Associate Professor

Neurological Surgery

Bjoern Schwer, MD, PhD is investigating molecular processes that affect genomic stability in developing and mature neural lineage cells, and the role of these processes in development, aging and cancers of the brain.

Licia Selleri, PhD, MD

Professor

Orofacial Sciences

Licia Selleri, MD, PhD studies the genetic and regulatory control of cranial and appendicular morphogenesis in embryonic development, evolution and disease using different model and non-model organisms.

Kevin Shannon, MD

Professor

Pediatrics

Kevin Shannon, MD studies signaling mechanisms that regulate the growth and differentiation of normal and leukemic stem cells. He is particularly interested in the genetic and biochemical basis of inherited leukemia predispositions and the regulation of hematopoietic stem cell and progenitor cell growth by Ras signaling.

Yin Shen, PhD

Professor

Neurology

Yin Shen, PhD utilizes genomics tools to investigate the genetic and epigenetic contributions to gene regulation in development and diseases.

Dean Sheppard, MD

Professor

Medicine

Dean Sheppard, MD, PhD studies the role of integrins and signaling mechanisms in cell and tissue interactions in the lung, specifically in lung injury and fibrosis.

Brian Shy, MD, PhD

Assistant Professor

Laboratory Medicine

Brian Shy, MD, PhD directs GMP manufacturing efforts for cell and gene therapies at UCSF. His lab employs genome and epigenome engineering tools to enhance the safety and potency of cellular therapies, improve manufacturing methods, and develop new treatments for cancer, inherited immune disorders, and infectious disease.

Julie Sneddon, PhD

Assistant Professor

Cell and Tissue Biology

Julie Sneddon, PhD studies pancreatic development and type I diabetes, employing the tools of stem cell biology, developmental biology, genomics and tissue engineering.

Matt Springer, PhD

Professor

Medicine

Matthew Springer, PhD studies cell and gene therapies for ischemic diseases to aid in tissue revascularization, preservation and potentially regeneration. He also researches vascular endothelial function and its response to diet and cigarette smoke exposure.

Deepak Srivastava, MD

Professor

M_PEDS-CARDIOLOGY

Our laboratory focuses on understanding the causes of heart disease and on using knowledge of cardiac developmental pathways to devise novel therapeutic approaches for human cardiac disorders. Specifically, we study the molecular events regulating early and late developmental decisions that instruct progenitor cells to adopt a cardiac cell fate and subsequently fashion a functioning heart. We focus on transcriptional and post-transcriptional steps, including those involving microRNAs. We have leveraged this knowledge to reprogram fibroblasts directly into cardiomyocyte-like cells for regenerative purposes. We also seek to identify the causes of human cardiovascular disease by applying modern genetic technologies for the study of complex traits such as congenital heart disease. By using a spectrum of approaches including mouse and human genetics, molecular and developmental biology, and biochemistry we hope to develop a broad understanding of the biology underlying cardiogenesis and cardiovascular disorders.

Hua Su, MD

Professor

Anesthesia

Hua Su, MD studies gene and cell based therapies for cerebral vascular diseases, including stroke.

Qizhi Tang, PhD

Professor

Surgery

Qizhi Tang, PhD is working on developing regulatory T cell therapies to induce immune tolerance so that foreign tissue can be transplanted without the need for life-long immunosuppression.