People

Arnold Kriegstein, MD, PhD studies how embryonic neural stem cells and progenitor cells produce neurons with the goal of developing treatments for brain disorders, such as autism and Parkinson’s disease.

Matthew Krummel, PhD uses in situ imaging of proximal molecular events in the thymus to determine how signaling proceeds in the context of tissues and organs.

Diana Laird, PhD studies the development and regulation of primordial germ cells, stem cells in the embryo that give rise to eggs or sperm.

Randall Lee, MD, PhD is an adult electrophysiologist interested in tissue engineering approaches to target stem cell therapies in the heart, including the use of antibodies and biopolymers.

Jingjing Li, PhD researches large-scale analysis of disease genomes by integrating multi-omics data, evolutionary insights, electronic health records, as well as digitized clinical traits from imaging and wearable sensor readouts.

Daniel Lim, MD, PhD studies the role of chromatin remodeling factors in the regulation of neural stem cell fate. By defining the genetic programs and molecular mechanisms of neurogenesis, he hopes to develop therapies for neurodegenerative diseases and injury.

Jeffrey Lotz, PhD studies the use of stem cells, growth factors and synthetic matrices for tissue engineered regeneration and healing of vertebral discs. His focus is on defining the biomechanical and inflammatory factors that cause back pain and on cell culture and animal models of disc degeneration.

Clifford Lowell, MD, PhD studies the role of Src family kinases and the Syk tyrosine kinase in signal transduction pathways within hematopoietic cells.

Tom Lue, MD studies adipose tissue derived stem cells and progenitor cells.

UCSF Broad Stem Cell Center Director, Tippi MacKenzie, MD, is focused on developing safe and effective stem cell transplantation and other therapies for fetuses with congenital anomalies. In utero stem cell transplantation could treat diseases in which stem cells are missing or mutated, such as immunodeficiencies, inborn errors of metabolism, or muscular dystrophy.

Jacquelyn Maher, MD studies basic mechanisms of hepatotoxicity with a focus on clinically relevant diseases, such as drug-induced liver injury and nonalcoholic steatohepatitis (NASH).

Sharmila Majumdar, PhD is working on developing imaging techniques to track stem cells in vivo.