Diabetes

Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function.

Diabetes

Villalta SA, Lang J, Kubeck S, Kabre B, Szot GL, Calderon B, Wasserfall C, Atkinson MA, Brekken RA, Pullen N, Arch RH, Bluestone JA

2155-P: Peripheral Nervous System Innervation of the Developing Pancreas.

Diabetes

SEAN DE LA O, LAUREN BYRNES, DANIEL M. WONG, SARAH KNOX, JULIE B. SNEDDON

Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study.

Diabetes

Seyfert-Margolis V, Gisler TD, Asare AL, Wang RS, Dosch HM, Brooks-Worrell B, Eisenbarth GS, Palmer JP, Greenbaum CJ, Gitelman SE, Nepom GT, Bluestone JA, Herold KC

Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders.

Diabetes

Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA, AbATE Study Team

The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet �-Cell Function.

Diabetes

Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R

MicroRNA expression is required for pancreatic islet cell genesis in the mouse.

Diabetes

Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS

Recommendations for the definition of clinical responder in insulin preservation studies.

Diabetes

Beam CA, Gitelman SE, Palmer JP, Type 1 Diabetes TrialNet Study Group

Serotonin Regulates Adult �-Cell Mass by Stimulating Perinatal �-Cell Proliferation.

Diabetes

Moon JH, Kim YG, Kim K, Osonoi S, Wang S, Saunders DC, Wang J, Yang K, Kim H, Lee J, Jeong JS, Banerjee RR, Kim SK, Wu Y, Mizukami H, Powers AC, German MS, Kim H

Prevention of autoimmune diabetes with nonactivating anti-CD3 monoclonal antibody.

Diabetes

Herold KC, Bluestone JA, Montag AG, Parihar A, Wiegner A, Gress RE, Hirsch R

Regulated beta-cell regeneration in the adult mouse pancreas.

Diabetes

Cano DA, Rulifson IC, Heiser PW, Swigart LB, Pelengaris S, German M, Evan GI, Bluestone JA, Hebrok M

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