Cancer research

Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells.

Cancer research

You L, He B, Uematsu K, Xu Z, Mazieres J, Lee A, McCormick F, Jablons DM

Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo.

Cancer research

Wendel HG, Malina A, Zhao Z, Zender L, Kogan SC, Cordon-Cardo C, Pelletier J, Lowe SW

Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.

Cancer research

Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, Weiss WA, Jenkins RB, Largaespada DA

Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.

Cancer research

Costello JF, Berger MS, Huang HS, Cavenee WK

Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.

Cancer research

Lin WC, Rajbhandari N, Liu C, Sakamoto K, Zhang Q, Triplett AA, Batra SK, Opavsky R, Felsher DW, DiMaio DJ, Hollingsworth MA, Morris JP, Hebrok M, Witkiewicz AK, Brody JR, Rui H, Wagner KU

Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process.

Cancer research

Ohba S, Mukherjee J, Johannessen TC, Mancini A, Chow TT, Wood M, Jones L, Mazor T, Marshall RE, Viswanath P, Walsh KM, Perry A, Bell RJ, Phillips JJ, Costello JF, Ronen SM, Pieper RO

Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.

Cancer research

Holst CR, Nuovo GJ, Esteller M, Chew K, Baylin SB, Herman JG, Tlsty TD

Pages