Cancer research

Topoisomerase II inhibition and altered kinetics of formation and repair of nitrosourea and cisplatin-induced DNA interstrand cross-links and cytotoxicity in human glioblastoma cells.

Cancer research

Ali-Osman F, Berger MS, Rajagopal S, Spence A, Livingston RB

Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.

Cancer research

Costa BM, Smith JS, Chen Y, Chen J, Phillips HS, Aldape KD, Zardo G, Nigro J, James CD, Fridlyand J, Reis RM, Costello JF

Separate pathways for p53 induction by ionizing radiation and N-(phosphonoacetyl)-L-aspartate.

Cancer research

Chen CY, Hall I, Lansing TJ, Gilmer TM, Tlsty TD, Kastan MB

Canonical wnt signaling is required for pancreatic carcinogenesis.

Cancer research

Zhang Y, Morris JP, Yan W, Schofield HK, Gurney A, Simeone DM, Millar SE, Hoey T, Hebrok M, Pasca di Magliano M

Genome-wide screen for allelic imbalance in a mouse model for neuroblastoma.

Cancer research

Weiss WA, Godfrey T, Francisco C, Bishop JM

A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.

Cancer research

Maertens O, McCurrach ME, Braun BS, De Raedt T, Epstein I, Huang TQ, Lauchle JO, Lee H, Wu J, Cripe TP, Clapp DW, Ratner N, Shannon K, Cichowski K

Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.

Cancer research

Anders M, Christian C, McMahon M, McCormick F, Korn WM

Abstract 3621: 3D spatial sampling and integrated omics reveal sources and patterning of intratumoral heterogeneity in glioblastoma.

Cancer research

Radhika Mathur, Qixuan Wang, Patrick Schupp, Ana Nikolic, Takafumi Yamaguchi, Stephanie Hilz, Chibo Hong, Ivan Smirnov, Marisa LaFontaine, Joanna Phillips, Susan Chang, Yan Li, Janine Lupo, Paul Boutros, Marco Gallo, Michael Oldham, Feng Yue, Joseph Costello

Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model.

Cancer research

Saito R, Bringas JR, Panner A, Tamas M, Pieper RO, Berger MS, Bankiewicz KS

Detection of activated Mr 21,000 protein, the product of ras oncogenes, using antibodies with specificity for amino acid 12.

Cancer research

Wong G, Arnheim N, Clark R, McCabe P, Innis M, Aldwin L, Nitecki D, McCormick F

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