Nature immunology

The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.

Nature immunology

Shiow LR, Roadcap DW, Paris K, Watson SR, Grigorova IL, Lebet T, An J, Xu Y, Jenne CN, Föger N, Sorensen RU, Goodnow CC, Bear JE, Puck JM, Cyster JG

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.

Nature immunology

Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, Basu U, Alt FW, Tang J, Oltz EM, Murphy TL, Murphy KM

High endothelial venules through a transcriptomics lens.

Nature immunology

Rosen SD, Daneman R

The subtle hands of self-reactivity in peripheral T cells.

Nature immunology

Mujal AM, Krummel M

An essential role for the Zn2+ transporter ZIP7 in B cell development.

Nature immunology

Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm BC, Ma CS, Sims D, van den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de la Morena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S

When ligand becomes receptor--tolerance via B7 signaling on DCs.

Nature immunology

Finger EB, Bluestone JA

Surface-bound chemokines capture and prime T cells for synapse formation.

Nature immunology

Friedman RS, Jacobelli J, Krummel MF

Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells.

Nature immunology

Grigorova IL, Schwab SR, Phan TG, Pham TH, Okada T, Cyster JG

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