Nature immunology

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity.

Nature immunology

Schumann K, Raju SS, Lauber M, Kolb S, Shifrut E, Cortez JT, Skartsis N, Nguyen VQ, Woo JM, Roth TL, Yu R, Nguyen MLT, Simeonov DR, Nguyen DN, Targ S, Gate RE, Tang Q, Bluestone JA, Spitzer MH, Ye CJ, Marson A

NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.

Nature immunology

Zompi S, Hamerman JA, Ogasawara K, Schweighoffer E, Tybulewicz VL, Di Santo JP, Lanier LL, Colucci F

Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces.

Nature immunology

Woolf E, Grigorova I, Sagiv A, Grabovsky V, Feigelson SW, Shulman Z, Hartmann T, Sixt M, Cyster JG, Alon R

The sickness unto Deaf.

Nature immunology

Gardner JM, Anderson MS

Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells.

Nature immunology

Gérard A, Khan O, Beemiller P, Oswald E, Hu J, Matloubian M, Krummel MF

Lost GRP on cytotoxicity?

Nature immunology

Roose JP

B cells on the front line.

Nature immunology

Cyster JG

A CD22-Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity.

Nature immunology

Ballet R, Brennan M, Brandl C, Feng N, Berri J, Cheng J, Ocón B, Alborzian Deh Sheikh A, Marki A, Bi Y, Abram CL, Lowell CA, Tsubata T, Greenberg HB, Macauley MS, Ley K, Nitschke L, Butcher EC

A single class II myosin modulates T cell motility and stopping, but not synapse formation.

Nature immunology

Jacobelli J, Chmura SA, Buxton DB, Davis MM, Krummel MF

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

Nature immunology

Link A, Vogt TK, Favre S, Britschgi MR, Acha-Orbea H, Hinz B, Cyster JG, Luther SA

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