Nature immunology

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

Nature immunology

Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, Azuma M, Krummel MF, Bluestone JA

Regulatory T cells: recommendations to simplify the nomenclature.

Nature immunology

Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF

Lost GRP on cytotoxicity?

Nature immunology

Roose JP

B cells on the front line.

Nature immunology

Cyster JG

A CD22-Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity.

Nature immunology

Ballet R, Brennan M, Brandl C, Feng N, Berri J, Cheng J, Ocón B, Alborzian Deh Sheikh A, Marki A, Bi Y, Abram CL, Lowell CA, Tsubata T, Greenberg HB, Macauley MS, Ley K, Nitschke L, Butcher EC

A single class II myosin modulates T cell motility and stopping, but not synapse formation.

Nature immunology

Jacobelli J, Chmura SA, Buxton DB, Davis MM, Krummel MF

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

Nature immunology

Link A, Vogt TK, Favre S, Britschgi MR, Acha-Orbea H, Hinz B, Cyster JG, Luther SA

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

Nature immunology

Randall KL, Lambe T, Johnson AL, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, Deenick EK, Tangye SG, Chan TD, Camidge T, Brink R, Vinuesa CG, Batista FD, Cornall RJ, Goodnow CC

Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.

Nature immunology

Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S

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