Molecular and cellular biology

Protein kinase Cδ promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance.

Molecular and cellular biology

Limnander A, Zikherman J, Lau T, Leitges M, Weiss A, Roose JP

Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases.

Molecular and cellular biology

Brdicka T, Kadlecek TA, Roose JP, Pastuszak AW, Weiss A

The insulin gene contains multiple transcriptional elements that respond to glucose.

Molecular and cellular biology

German MS, Wang J

Abstract LB-306: The Ras exchange factor RasGRP1 opposes proliferative EGFR-SOS1 Ras signals and restricts intestinal epithelial cell growth.

Molecular and cellular biology

Philippe Depeille, Linda M. Henricks, Robert van de Ven, Ed Lemmens, Mary Matli, Kevin M. Haigis, David Donner, Robert Warren, Jeroen P. Roose

Cooperation of Cytokine Signaling with Chimeric Transcription Factors in Leukemogenesis: PML-Retinoic Acid Receptor Alpha Blocks Growth Factor-Mediated Differentiation.

Molecular and cellular biology

Vernon T. Phan, David B. Shultz, Bao-Tran H. Truong, Timothy J. Blake, Anna L. Brown, Thomas J. Gonda, Michelle M. Le Beau, Scott C. Kogan

Methylation-related chromatin structure is associated with exclusion of transcription factors from and suppressed expression of the O-6-methylguanine DNA methyltransferase gene in human glioma cell lines.

Molecular and cellular biology

Costello JF, Futscher BW, Kroes RA, Pieper RO

Abstract 2075: Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia.

Molecular and cellular biology

Zhengshan Chen, Seyedmehdi Shojaee, Maike Buchner, Huimin Geng, Jae Woong Lee, Lars Klemm, Eugene Park, Ying Xim Tan, Anne Satterthwaite, Elisabeth Paietta, Stephen P. Hunger, Mignon L. Loh, Jae U. Jung, John E. Coligan, Silvia Bolland, Tak W. Mak, Andre Limnander, Hassan Jumaa, Michael Reth, Arthur Weiss, Clifford A. Lowell, Markus Müschen

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development.

Molecular and cellular biology

Chen MH, Gao N, Kawakami T, Chuang PT

Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential.

Molecular and cellular biology

Dickinson LA, Kohwi-Shigematsu T

Abstract 2138: RasGRP3 mediates MAPK pathway activation in GNAQ mutant uveal melanoma.

Molecular and cellular biology

Xu Chen, Qiuxia Wu, Philippe Depeille, Jeroen P. Roose, Boris C. Bastian

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