The Journal of cell biology

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.

Stormo AED, Shavarebi F, FitzGibbon M, Earley EM, Ahrendt H, Lum LS, Verschueren E, Swaney DL, Skibinski G, Ravisankar A, van Haren J, Davis EJ, Johnson JR, Von Dollen J, Balen C, Porath J, Crosio C, Mirescu C, Iaccarino C, Dauer WT, Nichols RJ, Wittmann T, Cox TC, Finkbeiner S, Krogan NJ, Oakes SA, Hiniker A

Molecular requirements for actin-based lamella formation in Drosophila S2 cells.

The Journal of cell biology

Rogers SL, Wiedemann U, Stuurman N, Vale RD

Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

The Journal of cell biology

Braren R, Hu H, Kim YH, Beggs HE, Reichardt LF, Wang R

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.

The Journal of cell biology

Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS