Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline. eLife Jeremy M Shea, Saul A Villeda
Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. eLife Wong JC, Weinfurtner KM, Alzamora Mdel P, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen SC, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, Shannon K
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice. eLife Kuhn JA, Vainchtein ID, Braz J, Hamel K, Bernstein M, Craik V, Dahlgren MW, Ortiz-Carpena J, Molofsky AB, Molofsky AV, Basbaum AI
Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization. eLife Hill SA, Blaeser AS, Coley AA, Xie Y, Shepard KA, Harwell CC, Gao WJ, Garcia ADR
Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. eLife Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF
Ciliary Hedgehog signaling regulates cell survival to build the facial midline. eLife Abrams SR, Reiter JF
Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'. eLife Landegren N, Rosen LB, Freyhult E, Eriksson D, Fall T, Smith G, Ferre EMN, Brodin P, Sharon D, Snyder M, Lionakis M, Anderson M, Kämpe O