Cancer research

STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma.

Cancer research

Lau J, Ilkhanizadeh S, Wang S, Miroshnikova YA, Salvatierra NA, Wong RA, Schmidt C, Weaver VM, Weiss WA, Persson AI

Abstract C20: Smpd3 augments chemotherapy and thwarts PDA progression.

Cancer research

Audrey M. Hendley, Atsushi Urano, Natanya R. Kerper, Phat Duong, Peter Bailey, David K. Chang, Andrew V. Biankin, David W. Dawson, Grace Kim, Robert L. Raffai, Matthias Hebrok

Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach.

Cancer research

Fan QW, Specht KM, Zhang C, Goldenberg DD, Shokat KM, Weiss WA

Abstract C036: Restoration of T effector cells function by targeting senescent cancer-associated fibroblast in tumor microenvironment of stroma-rich cancers.

Cancer research

Yao Wang, Hara Apostolopoulou, Arjun Sanyal, Hong Sun, Cynthia Sieland, Kavya Gupta, Jiayu Ye, David Gibbs, Paul Wong, Ntranos Vasilis, Sui Huang, James Gardner, Ajay Maker, Thea Tlsty, Anil Bhushan, Tamara Alliston

Ratios between the abundance of messenger RNA and the corresponding protein of two growth-related genes, c-myc and vimentin, in leukemia blast cells.

Cancer research

Ferrari S, Tagliafico E, D'Incá M, Ceccherelli G, Manfredini R, Selleri L, Donelli A, Sacchi S, Torelli G, Torelli U

PIK3CA cooperates with other phosphatidylinositol 3'-kinase pathway mutations to effect oncogenic transformation.

Cancer research

Oda K, Okada J, Timmerman L, Rodriguez-Viciana P, Stokoe D, Shoji K, Taketani Y, Kuramoto H, Knight ZA, Shokat KM, McCormick F

Defective G2 checkpoint function in cells from individuals with familial cancer syndromes.

Cancer research

Paules RS, Levedakou EN, Wilson SJ, Innes CL, Rhodes N, Tlsty TD, Galloway DA, Donehower LA, Tainsky MA, Kaufmann WK

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