Cancer research | Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF

Investigation of resistance to DNA cross-linking agents in 9L cell lines with different sensitivities to chloroethylnitrosoureas.

Cancer research

Bodell WJ, Gerosa M, Aida T, Berger MS, Rosenblum ML

p38 regulates cyclooxygenase-2 in human mammary epithelial cells and is activated in premalignant tissue.

Cancer research

Gauthier ML, Pickering CR, Miller CJ, Fordyce CA, Chew KL, Berman HK, Tlsty TD

Abstract P5-06-02: A gene expression meta-analysis identifies microenvironment differences in cellular composition and cell-cell interactions associated with breast cancer invasion.

Cancer research

Adam Officer, Andre Dempsey, Farnaz Hasteh, Michal Slyper, Asa Segerstolpe, Joanna Klughammer, Judit Jane-Valbuena, Orit Rozenblatt-Rosen, Lyndsay Murrow, Zev Gartner, Aviv Regev, Christina Yau, Pablo Tamayo, Olivier Harismendy

O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics.

Cancer research

Silber JR, Bobola MS, Ghatan S, Blank A, Kolstoe DD, Berger MS

Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term T�RI/II kinase inhibition with LY2109761.

Cancer research

Connolly EC, Saunier EF, Quigley D, Luu MT, De Sapio A, Hann B, Yingling JM, Akhurst RJ

Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas.

Cancer research

Ali-Osman F, Giblin J, Berger M, Murphy MJ, Rosenblum ML

Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8.

Cancer research

Hong C, Maunakea A, Jun P, Bollen AW, Hodgson JG, Goldenberg DD, Weiss WA, Costello JF

Abstract 3420: Tgfbm3b is a natural germline genetic variant that modifies anti-tumor responses to anti-PD-1 immunotherapy through its action on the tumor microenvironment.

Cancer research

Szu-Ying Chen, Ons Mamai, Rosemary Akhurst

Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.

Cancer research

Ulaner GA, Hu JF, Vu TH, Giudice LC, Hoffman AR

Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms.

Cancer research

Choi G, Huang B, Pinarbasi E, Braunstein SE, Horvai AE, Kogan S, Bhatia S, Faddegon B, Nakamura JL

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