Scott Baraban, PhD

Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development.

bioRxiv : the preprint server for biology

Uribe-Salazar JM, Kaya G, Weyenberg K, Radke B, Hino K, Soto DC, Shiu JL, Zhang W, Ingamells C, Haghani NK, Xu E, Rosas J, Simó S, Miesfeld J, Glaser T, Baraban SC, Jao LE, Dennis MY

Testing of putative antiseizure medications in a preclinical Dravet syndrome zebrafish model.

Brain communications

Whyte-Fagundes PA, Vance A, Carroll A, Figueroa F, Manukyan C, Baraban SC

Host brain environmental influences on transplanted medial ganglionic eminence progenitors.

Scientific reports

Paterno R, Vu T, Hsieh C, Baraban SC

Testing of putative antiseizure drugs in a preclinical Dravet syndrome zebrafish model.

bioRxiv : the preprint server for biology

Whyte-Fagundes P, Vance A, Carroll A, Figueroa F, Manukyan C, Baraban SC

Cell therapy for neurological disorders: Progress towards an embryonic medial ganglionic eminence progenitor-based treatment.

Frontiers in neuroscience

Righes Marafiga J, Baraban SC

Clemizole and trazodone are effective antiseizure treatments in a zebrafish model of STXBP1 disorder.

Epilepsia open

Moog M, Baraban SC

Xenotransplantation of porcine progenitor cells in an epileptic California sea lion (Zalophus californianus): illustrative case.

Journal of neurosurgery. Case lessons

Simeone CA, Andrews JP, Johnson SP, Casalia M, Kochanski R, Chang EF, Cameron D, Dennison S, Inglis B, Scott G, Kruse-Elliott K, Okonski FF, Calvo E, Goulet K, Robles D, Griffin-Stence A, Kuiper E, Krasovec L, Field CL, Hoard VF, Baraban SC

Hippocampal gamma and sharp-wave ripple oscillations are altered in a Cntnap2 mouse model of autism spectrum disorder.

Cell reports

Paterno R, Marafiga JR, Ramsay H, Li T, Salvati KA, Baraban SC

A zebrafish-centric approach to antiepileptic drug development.

Disease models & mechanisms

Baraban SC

Maximally selective single-cell target for circuit control in epilepsy models.

Neuron

Hadjiabadi D, Lovett-Barron M, Raikov IG, Sparks FT, Liao Z, Baraban SC, Leskovec J, Losonczy A, Deisseroth K, Soltesz I

Phenotypic analysis of catastrophic childhood epilepsy genes.

Communications biology

Griffin A, Carpenter C, Liu J, Paterno R, Grone B, Hamling K, Moog M, Dinday MT, Figueroa F, Anvar M, Ononuju C, Qu T, Baraban SC

In�vivo calcium imaging reveals disordered interictal network dynamics in epileptic stxbp1b zebrafish.

iScience

Liu J, Salvati KA, Baraban SC

Interneuron Origins in the Embryonic Porcine Medial Ganglionic Eminence.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Casalia ML, Li T, Ramsay H, Ross PJ, Paredes MF, Baraban SC

Enhancing glucose metabolism via gluconeogenesis is therapeutic in a zebrafish model of Dravet syndrome.

Brain communications

Banerji R, Huynh C, Figueroa F, Dinday MT, Baraban SC, Patel M

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model.

Frontiers in pharmacology

Griffin A, Anvar M, Hamling K, Baraban SC

Imaging epilepsy in larval zebrafish.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Burrows DRW, Samarut ?, Liu J, Baraban SC, Richardson MP, Meyer MP, Rosch RE

Interneuron deficits in neurodevelopmental disorders: Implications for disease pathology and interneuron-based therapies.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Paterno R, Casalia M, Baraban SC

Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome.

Brain communications

Griffin AL, Jaishankar P, Grandjean JM, Olson SH, Renslo AR, Baraban SC

Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish.

eNeuro

Liu J, Baraban SC

Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis.

Cerebral cortex (New York, N.Y. : 1991)

Pla R, Stanco A, Howard MA, Rubin AN, Vogt D, Mortimer N, Cobos I, Potter GB, Lindtner S, Price JD, Nord AS, Visel A, Schreiner CE, Baraban SC, Rowitch DH, Rubenstein JLR

Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening.

Frontiers in pharmacology

Griffin A, Hamling KR, Hong S, Anvar M, Lee LP, Baraban SC

Publisher Correction: PAFAH1B1 haploinsufficiency disrupts GABA neurons and synaptic E/I balance in the dentate gyrus.

Scientific reports

Dinday MT, Girskis KM, Lee S, Baraban SC, Hunt RF

Persistent seizure control in epileptic mice transplanted with gamma-aminobutyric acid progenitors.

Annals of neurology

Casalia ML, Howard MA, Baraban SC

Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma.

Human molecular genetics

Protas ME, Weh E, Footz T, Kasberger J, Baraban SC, Levin AV, Katz LJ, Ritch R, Walter MA, Semina EV, Gould DB

PAFAH1B1 haploinsufficiency disrupts GABA neurons and synaptic E/I balance in the dentate gyrus.

Scientific reports

Dinday MT, Girskis KM, Lee S, Baraban SC, Hunt RF

Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome.

eNeuro

Grone BP, Qu T, Baraban SC

Catastrophic Epilepsies of Childhood.

Annual review of neuroscience

Howard MA, Baraban SC

Viral tracing of presynaptic inputs to newly born dentate granule cells in a rodent model of mesial temporal lobe epilepsy.

Annals of neurology

Baraban SC

Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner.

eNeuro

Hsieh JY, Baraban SC

Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome.

Brain : a journal of neurology

Griffin A, Hamling KR, Knupp K, Hong S, Lee LP, Baraban SC

A Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish.

Scientific reports

Hong S, Lee P, Baraban SC, Lee LP

Synaptic integration of transplanted interneuron progenitor cells into native cortical networks.

Journal of neurophysiology

Howard MA, Baraban SC

Advancing epilepsy treatment through personalized genetic zebrafish models.

Progress in brain research

Griffin A, Krasniak C, Baraban SC

Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome.

eNeuro

Kumar MG, Rowley S, Fulton R, Dinday MT, Baraban SC, Patel M

Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish.

PloS one

Grone BP, Marchese M, Hamling KR, Kumar MG, Krasniak CS, Sicca F, Santorelli FM, Patel M, Baraban SC

Interneuron Transplantation as a Treatment for Epilepsy.

Cold Spring Harbor perspectives in medicine

Hunt RF, Baraban SC

Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome

eNeuro

Dinday MT, Baraban SC

Animal models in epilepsy research: legacies and new directions.

Nature neuroscience

Grone BP, Baraban SC

NPAS1 represses the generation of specific subtypes of cortical interneurons.

Neuron

Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JL

14-3-3e and ? regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A

GABAB receptors in maintenance of neocortical circuit function.

Experimental neurology

Sebe JY, Looke-Stewart E, Baraban SC

Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position.

Neuron

Vogt D, Hunt RF, Mandal S, Sandberg M, Silberberg SN, Nagasawa T, Yang Z, Baraban SC, Rubenstein JL

Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.

Neuron

Silbereis JC, Nobuta H, Tsai HH, Heine VM, McKinsey GL, Meijer DH, Howard MA, Petryniak MA, Potter GB, Alberta JA, Baraban SC, Stiles CD, Rubenstein JL, Rowitch DH

What new modeling approaches will help us identify promising drug treatments?

Advances in experimental medicine and biology

Baraban SC, L?scher W

Bidirectional homeostatic plasticity induced by interneuron cell death and transplantation in vivo.

Proceedings of the National Academy of Sciences of the United States of America

Howard MA, Rubenstein JL, Baraban SC

Neocortical integration of transplanted GABA progenitor cells from wild type and GABA(B) receptor knockout mouse donors.

Neuroscience letters

Sebe JY, Looke-Stewart E, Dinday MT, Alvarez-Buylla A, Baraban SC

GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior.

Nature neuroscience

Hunt RF, Girskis KM, Rubenstein JL, Alvarez-Buylla A, Baraban SC

Use of "MGE enhancers" for labeling and selection of embryonic stem cell-derived medial ganglionic eminence (MGE) progenitors and neurons.

PloS one

Chen YJ, Vogt D, Wang Y, Visel A, Silberberg SN, Nicholas CR, Danjo T, Pollack JL, Pennacchio LA, Anderson S, Sasai Y, Baraban SC, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL

Forebrain Electrophysiological Recording in Larval Zebrafish.

Journal of Visualized Experiments

Scott C. Baraban

Forebrain electrophysiological recording in larval zebrafish.

Journal of visualized experiments : JoVE

Baraban SC

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.

Nature communications

Baraban SC, Dinday MT, Hortopan GA

The devil is in the details: stem cells for the treatment of epilepsy.

Epilepsy currents

Hunt RF, Baraban SC

ALLN rescues an in vitro excitatory synaptic transmission deficit in Lis1 mutant mice.

Journal of neurophysiology

Sebe JY, Bershteyn M, Hirotsune S, Wynshaw-Boris A, Baraban SC

Intrinsically determined cell death of developing cortical interneurons.

Nature

Southwell DG, Paredes MF, Galvao RP, Jones DL, Froemke RC, Sebe JY, Alfaro-Cervello C, Tang Y, Garcia-Verdugo JM, Rubenstein JL, Baraban SC, Alvarez-Buylla A

LIS1 deficiency promotes dysfunctional synaptic integration of granule cells generated in the developing and adult dentate gyrus.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Hunt RF, Dinday MT, Hindle-Katel W, Baraban SC

Familial cortical myoclonus with a mutation in NOL3.

Annals of neurology

Russell JF, Steckley JL, Coppola G, Hahn AF, Howard MA, Kornberg Z, Huang A, Mirsattari SM, Merriman B, Klein E, Choi M, Lee HY, Kirk A, Nelson-Williams C, Gibson G, Baraban SC, Lifton RP, Geschwind DH, Fu YH, Pt?cek LJ

Cell Therapy Using GABAergic Neural Progenitors.

Jasper\u0027s Basic Mechanisms of the Epilepsies

Stewart A. Anderson, Scott C. Baraban

A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors.

Experimental neurology

Hunt RF, Hortopan GA, Gillespie A, Baraban SC

Expression and function of KCNQ channels in larval zebrafish.

Developmental neurobiology

Chege SW, Hortopan GA, T Dinday M, Baraban SC

Impaired neural development in a zebrafish model for Lowe syndrome.

Human molecular genetics

Ramirez IB, Pietka G, Jones DR, Divecha N, Alia A, Baraban SC, Hurlstone AF, Lowe M

Aberrant expression of genes necessary for neuronal development and Notch signaling in an epileptic mind bomb zebrafish.

Developmental dynamics : an official publication of the American Association of Anatomists

Hortopan GA, Baraban SC

Deletion of Dlx1 results in reduced glutamatergic input to hippocampal interneurons.

Journal of neurophysiology

Jones DL, Howard MA, Stanco A, Rubenstein JL, Baraban SC

Chapter 50 Animal Models of Epilepsy.

Youmans Neurological Surgery

Maria Elisa Calcagnotto, Scott C. Baraban

The promise of an interneuron-based cell therapy for epilepsy.

Developmental neurobiology

Sebe JY, Baraban SC

Cell therapy for epilepsy using GABAergic neural progenitors.

Epilepsia

Stewart A. Anderson, Scott C. Baraban

Spontaneous seizures and altered gene expression in GABA signaling pathways in a mind bomb mutant zebrafish.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Hortopan GA, Dinday MT, Baraban SC

Robust tonic GABA currents can inhibit cell firing in mouse newborn neocortical pyramidal cells.

The European journal of neuroscience

Sebe JY, Looke-Stewart EC, Estrada RC, Baraban SC

Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL

Zebrafish as a model for studying genetic aspects of epilepsy.

Disease models & mechanisms

Hortopan GA, Dinday MT, Baraban SC

Seizures, enhanced excitation, and increased vesicle number in Lis1 mutant mice.

Annals of neurology

Greenwood JS, Wang Y, Estrada RC, Ackerman L, Ohara PT, Baraban SC

Basic mechanisms of MCD in animal models.

Epileptic disorders : international epilepsy journal with videotape

Battaglia G, Becker AJ, LoTurco J, Represa A, Baraban SC, Roper SN, Vezzani A

Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice.

Proceedings of the National Academy of Sciences of the United States of America

Baraban SC, Southwell DG, Estrada RC, Jones DL, Sebe JY, Alfaro-Cervello C, García-Verdugo JM, Rubenstein JL, Alvarez-Buylla A

Inhibitory inputs to hippocampal interneurons are reorganized in Lis1 mutant mice.

Journal of neurophysiology

Jones DL, Baraban SC

PEDIATRIC EPILEPSY | Mechanisms of Epileptogenesis in Models of Pediatric Epilepsy Syndromes Associated with Brain Malformation.

Encyclopedia of Basic Epilepsy Research

S.C. Baraban

Zebrafish as a Simple Vertebrate Organism for Epilepsy Research.

Animal Models of Epilepsy

Scott C. Baraban

Aberrant dentate gyrus cytoarchitecture and fiber lamination in Lis1 mutant mice.

Hippocampus

Wang Y, Baraban SC

Developing cell transplantation for temporal lobe epilepsy.

Neurosurgical focus

Richardson RM, Barbaro NM, Alvarez-Buylla A, Baraban SC

Characterization of inhibitory circuits in the malformed hippocampus of Lis1 mutant mice.

Journal of neurophysiology

Jones DL, Baraban SC

A large-scale mutagenesis screen to identify seizure-resistant zebrafish.

Epilepsia

Baraban SC, Dinday MT, Castro PA, Chege S, Guyenet S, Taylor MR

Emerging epilepsy models: insights from mice, flies, worms and fish.

Current opinion in neurology

Baraban SC

Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1.

Annals of neurology

Wang Y, Greenwood JS, Calcagnotto ME, Kirsch HE, Barbaro NM, Baraban SC

Altered glutamate receptor - transporter expression and spontaneous seizures in rats exposed to methylazoxymethanol in utero.

Epilepsia

Harrington EP, Möddel G, Najm IM, Baraban SC

Granule cell dispersion and aberrant neurogenesis in the adult hippocampus of an LIS1 mutant mouse.

Developmental neuroscience

Wang Y, Baraban SC

Preface.

Developmental neuroscience

Samuel J. Pleasure, Scott C. Baraban

Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Paredes MF, Li G, Berger O, Baraban SC, Pleasure SJ

Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Alvarez-Dolado M, Calcagnotto ME, Karkar KM, Southwell DG, Jones-Davis DM, Estrada RC, Rubenstein JL, Alvarez-Buylla A, Baraban SC

A role for the mTOR pathway in surface expression of AMPA receptors.

Neuroscience letters

Wang Y, Barbaro MF, Baraban SC

Embryonic and early postnatal abnormalities contributing to the development of hippocampal malformations in a rodent model of dysplasia.

The Journal of comparative neurology

Paredes M, Pleasure SJ, Baraban SC

CHAPTER 15 Modeling Epilepsy and Seizures in Developing Zebrafish Larvae.

Models of Seizures and Epilepsy

SCOTT C. BARABAN

Contributing Authors.

Models of Seizures and Epilepsy

Massimo Avoli, Roy A. Bakay, Scott C. Baraban, Tallie Z. Baram, Stefania Bassanini, Giorgio Battaglia, Christophe Bernard, Edward H. Bertram, Ronald A. Browning, Paul S. Buckmaster, Daniel L. Burgess, Thomas Budde, Xiang Cai, Esper A. Cavalheiro, Wei-Ping Chen, Suzanne Clark, Miguel A. Cortez, Marco de Curtis, Antoine Depaulis, Marc A. Dichter, Céline Dinocourt, Céliné M. Dubé, F. Edward Dudek, Jerome Engel, Aristea S. Galanopoulou, Mary E. Gilbert, Jeffrey H. Goodman, Ali Gorji, Heidi Grabenstatter, Kevin D. Graber, Uwe Heinemann, Gregory L. Holmes, John R. Huguenard, John G.R. Jefferys, Frances E. Jensen, Phillip C. Jobe, Oliver Kann, Kevin M. Kelly, Irina Kharatishvilli, Rüdiger Köhling, Hana Kubová, Sanjay S. Kumar, João P. Leite, Laura Librizzi, Dean D. Lin, Wolfgang Löscher, Joseph J. LoTurco, Heiko J. Luhmann, Gilles van Luijtelaar, Pavel Mareš, Gary W. Mathern, Andrey M. Mazarati, Tracy K. McIntosh, Dan C. McIntyre, James O. McNamara, Luiz E. Mello, Solomon L. Moshé, Maria G. Naffah-Mazzacoratti, Astrid Nehlig, Prosper N'Gouemo, Jari Nissinen, Jeffrey L. Noebels, Michael W. Nestor, Andre Obenaus, Jeffrey Ockuly, Hans-Christian Pape, Asla Pitkänen, John Pollard, David A. Prince, Dominick P. Purpura, Raddy L. Ramos, Charles E. Ribak, Michael A. Rogawski, Steven N. Roper, Russell M. Sanchez, Raman Sankar, Sebastian Schuchmann, Philip A. Schwartzkroin, Laszlo Seress, Lee A. Shapiro, Yukiyoshi Shirasaka, Margaret N. Shouse, Misty Smith-Yockman, O. Carter Snead, Erwin-Josef Speckmann, Ajay Srivastava, Carl E. Stafstrom, Mark Stewart, Janet L. Stringer, Lucie Suchomelova, Thomas P. Sutula, Kerry W. Thompson, Scott M. Thompson, William J. Triggs, Yuto Ueda, Laura Uva, Libor Velíšek, Jana Velíšková, Matthew C. Walker, Claude Wasterlain, H. Jürgen Wenzel, H. Steve White, Karen S. Wilcox, Philip A. Williams, L. James Willmore, Robert K.S. Wong, Qian Zhao