Nature communications

Ultra-deep sequencing validates safety of CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells.

Nature communications

Cromer MK, Barsan VV, Jaeger E, Wang M, Hampton JP, Chen F, Kennedy D, Xiao J, Khrebtukova I, Granat A, Truong T, Porteus MH

αE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development.

Nature communications

Li CY, Hu J, Lu H, Lan J, Du W, Galicia N, Klein OD

Intracellular pH dynamics regulates intestinal stem cell lineage specification.

Nature communications

Liu Y, Reyes E, Castillo-Azofeifa D, Klein OD, Nystul T, Barber DL

Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity.

Nature communications

Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K

Sox9 regulates alternative splicing and pancreatic beta cell function.

Nature communications

Puri S, Maachi H, Nair G, Russ HA, Chen R, Pulimeno P, Cutts Z, Ntranos V, Hebrok M

Identification of Meibomian gland stem cell populations and mechanisms of aging.

Nature communications

Zhu X, Xu M, Portal C, Lin Y, Ferdinand A, Peng T, Morrisey EE, Dlugosz AA, Castellano JM, Lee V, Seykora JT, Wong SY, Iomini C, Millar SE

Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards.

Nature communications

Martin RM, Fowler JL, Cromer MK, Lesch BJ, Ponce E, Uchida N, Nishimura T, Porteus MH, Loh KM

Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization.

Nature communications

Agnew C, Ayaz P, Kashima R, Loving HS, Ghatpande P, Kung JE, Underbakke ES, Shan Y, Shaw DE, Hata A, Jura N

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