Todd Nystul, PhD

Associate Professor
Anatomy
+1 415 970-6967

Todd Nystul, PhD studies epithelial stem cells and their associated niche in the Drosophila ovary.

Publications: 

PROPEL: a scalable model for postbaccalaureate training to promote diversity in the biomedical workforce.

Journal of microbiology & biology education

Allen J, Abdiwahab E, Morris MD, Le Saux CJ, Betancur P, Ansel KM, Hernandez RD, Nystul TG

A High-Throughput Method for Quantifying Drosophila Fecundity.

Toxics

Gomez A, Gonzalez S, Oke A, Luo J, Duong JB, Esquerra RM, Zimmerman T, Capponi S, Fung JC, Nystul TG

A high-throughput method for quantifying Drosophila fecundity.

bioRxiv : the preprint server for biology

Gomez A, Gonzalez S, Oke A, Luo J, Duong JB, Esquerra RM, Zimmerman T, Capponi S, Fung JC, Nystul TG

Intracellular pH dynamics regulates intestinal stem cell lineage specification.

Nature communications

Liu Y, Reyes E, Castillo-Azofeifa D, Klein OD, Nystul T, Barber DL

A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling.

Cell stem cell

Castillo-Azofeifa D, Wald T, Reyes EA, Gallagher A, Schanin J, Vlachos S, Lamarche-Vane N, Bomidi C, Blutt S, Estes MK, Nystul T, Klein OD

Preparation of Drosophila Ovarioles for Single-Cell RNA Sequencing.

Methods in molecular biology (Clifton, N.J.)

Meyer N, Peralta J, Nystul T

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.

Science (New York, N.Y.)

Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbic M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, Shim J, Tattikota SG, Schnorrer F, Rust K, Nystul TG, Carvalho-Santos Z, Ribeiro C, Pal S, Mahadevaraju S, Przytycka TM, Allen AM, Goodwin SF, Berry CW, Fuller MT, White-Cooper H, Matunis EL, DiNardo S, Galenza A, O'Brien LE, Dow JAT, FCA Consortium§, Jasper H, Oliver B, Perrimon N, Deplancke B, Quake SR, Luo L, Aerts S, Agarwal D, Ahmed-Braimah Y, Arbeitman M, Ariss MM, Augsburger J, Ayush K, Baker CC, Banisch T, Birker K, Bodmer R, Bolival B, Brantley SE, Brill JA, Brown NC, Buehner NA, Cai XT, Cardoso-Figueiredo R, Casares F, Chang A, Clandinin TR, Crasta S, Desplan C, Detweiler AM, Dhakan DB, Donà E, Engert S, Floc'hlay S, George N, González-Segarra AJ, Groves AK, Gumbin S, Guo Y, Harris DE, Heifetz Y, Holtz SL, Horns F, Hudry B, Hung RJ, Jan YN, Jaszczak JS, Jefferis GSXE, Karkanias J, Karr TL, Katheder NS, Kezos J, Kim AA, Kim SK, Kockel L, Konstantinides N, Kornberg TB, Krause HM, Labott AT, Laturney M, Lehmann R, Leinwand S, Li J, Li JSS, Li K, Li K, Li L, Li T, Litovchenko M, Liu HH, Liu Y, Lu TC, Manning J, Mase A, Matera-Vatnick M, Matias NR, McDonough-Goldstein CE, McGeever A, McLachlan AD, Moreno-Roman P, Neff N, Neville M, Ngo S, Nielsen T, O'Brien CE, Osumi-Sutherland D, Özel MN, Papatheodorou I, Petkovic M, Pilgrim C, Pisco AO, Reisenman C, Sanders EN, Dos Santos G, Scott K, Sherlekar A, Shiu P, Sims D, Sit RV, Slaidina M, Smith HE, Sterne G, Su YH, Sutton D, Tamayo M, Tan M, Tastekin I, Treiber C, Vacek D, Vogler G, Waddell S, Wang W, Wilson RI, Wolfner MF, Wong YE, Xie A, Xu J, Yamamoto S, Yan J, Yao Z, Yoda K, Zhu R, Zinzen RP

Distinct roles of Bendless in regulating FSC niche competition and daughter cell differentiation.

Development (Cambridge, England)

Tatapudy S, Peralta J, Nystul T

Author Correction: A single-cell atlas and lineage analysis of the adult Drosophila ovary.

Nature communications

Rust K, Byrnes LE, Yu KS, Park JS, Sneddon JB, Tward AD, Nystul TG

A single-cell atlas and lineage analysis of the adult Drosophila ovary.

Nature communications

Rust K, Byrnes LE, Yu KS, Park JS, Sneddon JB, Tward AD, Nystul TG

Signal transduction in the early Drosophila follicle stem cell lineage.

Current opinion in insect science

Rust K, Nystul T

Drosophila anion exchanger 2 is required for proper ovary development and oogenesis.

Developmental biology

Benitez M, Tatapudy S, Liu Y, Barber DL, Nystul TG

Wingless promotes EGFR signaling in follicle stem cells to maintain self-renewal.

Development (Cambridge, England)

Kim-Yip RP, Nystul TG

Cell fate decisions: emerging roles for metabolic signals and cell morphology.

EMBO reports

Tatapudy S, Aloisio F, Barber D, Nystul T

Methods for Imaging Intracellular pH of the Follicle Stem Cell Lineage in Live <em>Drosophila</em> Ovarian Tissue.

Journal of Visualized Experiments

Sumitra Tatapudy, Marimar Benitez, Todd Nystul

Methods for Imaging Intracellular pH of the Follicle Stem Cell Lineage in Live Drosophila Ovarian Tissue.

Journal of visualized experiments : JoVE

Tatapudy S, Benitez M, Nystul T

Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation.

The Journal of cell biology

Ulmschneider B, Grillo-Hill BK, Benitez M, Azimova DR, Barber DL, Nystul TG

Enhancer-trap flippase lines for clonal analysis in the Drosophila ovary.

G3 (Bethesda, Md.)

Huang P, Sahai-Hernandez P, Bohm RA, Welch WP, Zhang B, Nystul T

Drosophila models of epithelial stem cells and their niches.

Wiley interdisciplinary reviews. Developmental biology

Sahai-Hernandez P, Castanieto A, Nystul TG

Stem cells and their niches: integrated units that maintain Drosophila tissues.

Cold Spring Harbor symposia on quantitative biology

Spradling AC, Nystul T, Lighthouse D, Morris L, Fox D, Cox R, Tootle T, Frederick R, Skora A

The carnegie protein trap library: a versatile tool for Drosophila developmental studies.

Genetics

Buszczak M, Paterno S, Lighthouse D, Bachman J, Planck J, Owen S, Skora AD, Nystul TG, Ohlstein B, Allen A, Wilhelm JE, Murphy TD, Levis RW, Matunis E, Srivali N, Hoskins RA, Spradling AC

Breaking out of the mold: diversity within adult stem cells and their niches.

Current opinion in genetics & development

Nystul TG, Spradling AC

Multiple types of niche control stem cells in drosophila adults.

Developmental biology

Allan Spradling, Benjamin Ohlstein, Michael Buszczak, Todd Nystul, Lucy Morris, Eva Decotto

Buying time in suspended animation.

Scientific American

Roth MB, Nystul T

Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America

Nystul TG, Roth MB

Suspended animation in C. elegans requires the spindle checkpoint.

Science (New York, N.Y.)

Nystul TG, Goldmark JP, Padilla PA, Roth MB

Giardia lamblia expresses a proteobacterial-like DnaK homolog.

Molecular biology and evolution

Morrison HG, Roger AJ, Nystul TG, Gillin FD, Sogin ML

Novel protein-disulfide isomerases from the early-diverging protist Giardia lamblia.

The Journal of biological chemistry

Knodler LA, Noiva R, Mehta K, McCaffery JM, Aley SB, Svärd SG, Nystul TG, Reiner DS, Silberman JD, Gillin FD