
Professor
Anatomy
+1 415 476-4622
Leanne Jones, PhD identifies conserved mechanisms that are used to regulate stem cell behavior and characterizes how such mechanisms are altered by aging and changes in metabolism.
Publications
Regeneration, Rejuvenation, and Replacement: Turning Back the Clock on Tissue Aging.
Cold Spring Harbor perspectives in biology
Neuroglian regulates Drosophila intestinal stem cell proliferation through enhanced signaling via the epidermal growth factor receptor.
Stem cell reports
Lipid Mediated Regulation of Adult Stem Cell Behavior.
Frontiers in cell and developmental biology
EGFR Signaling Stimulates Autophagy to Regulate Stem Cell Maintenance and Lipid Homeostasis in the Drosophila Testis.
Cell reports
Mitochondrial fission regulates germ cell differentiation by suppressing ROS-mediated activation of Epidermal Growth Factor Signaling in the Drosophila larval testis.
Scientific reports
DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging.
Cellular and molecular gastroenterology and hepatology
Mitochondrial fusion regulates lipid homeostasis and stem cell maintenance in the Drosophila testis.
Nature cell biology
Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging.
The Journal of cell biology
Tricellular junctions regulate intestinal stem cell behaviour to maintain homeostasis.
Nature cell biology
Regulation of Drosophila intestinal stem cell maintenance and differentiation by the transcription factor Escargot.
The EMBO journal
Persistent replicative stress alters polycomb phenotypes and tissue homeostasis in Drosophila melanogaster.
Cell reports
Regulation of adult stem cell behavior by nutrient signaling.
Cell cycle (Georgetown, Tex.)
Emerging models and paradigms for stem cell ageing.
Nature cell biology
Stem cell dynamics in response to nutrient availability.
Current biology : CB
Stem cells and the niche: a dynamic duo.
Cell stem cell
No place like home: anatomy and function of the stem cell niche.
Nature reviews. Molecular cell biology
Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis.
Cell stem cell
Aging and the germ line: where mortality and immortality meet.
Stem cell reviews
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.
Science (New York, N.Y.)
Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue.
Science (New York, N.Y.)