Leanne Jones, PhD

Professor
Anatomy
+1 415 476-4622

Leanne Jones, PhD identifies conserved mechanisms that are used to regulate stem cell behavior and characterizes how such mechanisms are altered by aging and changes in metabolism.

Publications: 

Regeneration, Rejuvenation, and Replacement: Turning Back the Clock on Tissue Aging.

Cold Spring Harbor perspectives in biology

Rando TA, Jones DL

Neuroglian regulates Drosophila intestinal stem cell proliferation through enhanced signaling via the epidermal growth factor receptor.

Stem cell reports

Resnik-Docampo M, Cunningham KM, Ruvalcaba SM, Choi C, Sauer V, Jones DL

Lipid Mediated Regulation of Adult Stem Cell Behavior.

Frontiers in cell and developmental biology

Cl?mot M, S?nos Demarco R, Jones DL

DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging.

Cellular and molecular gastroenterology and hepatology

Lewis SK, Nachun D, Martin MG, Horvath S, Coppola G, Jones DL

Mitochondrial fusion regulates lipid homeostasis and stem cell maintenance in the Drosophila testis.

Nature cell biology

Sênos Demarco R, Uyemura BS, D'Alterio C, Jones DL

Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging.

The Journal of cell biology

Koehler CL, Perkins GA, Ellisman MH, Jones DL

Tricellular junctions regulate intestinal stem cell behaviour to maintain homeostasis.

Nature cell biology

Resnik-Docampo M, Koehler CL, Clark RI, Schinaman JM, Sauer V, Wong DM, Lewis S, D'Alterio C, Walker DW, Jones DL

Escargot restricts niche cell to stem cell conversion in the Drosophila testis.

Cell reports

Voog J, Sandall SL, Hime GR, Resende LP, Loza-Coll M, Aslanian A, Yates JR, Hunter T, Fuller MT, Jones DL

Headcase promotes cell survival and niche maintenance in the Drosophila testis.

PloS one

Resende LP, Boyle M, Tran D, Fellner T, Jones DL

The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche.

Nature

Toledano H, D'Alterio C, Czech B, Levine E, Jones DL

Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.

Cell metabolism

Rera M, Bahadorani S, Cho J, Koehler CL, Ulgherait M, Hur JH, Ansari WS, Lo T, Jones DL, Walker DW

Regulation of adult stem cell behavior by nutrient signaling.

Cell cycle (Georgetown, Tex.)

Wang L, McLeod CJ, Jones DL

Emerging models and paradigms for stem cell ageing.

Nature cell biology

Jones DL, Rando TA

Stem cell dynamics in response to nutrient availability.

Current biology : CB

McLeod CJ, Wang L, Wong C, Jones DL

Dietary restriction enhances germline stem cell maintenance.

Aging cell

Mair W, McLeod CJ, Wang L, Jones DL

Stem cells and the niche: a dynamic duo.

Cell stem cell

Voog J, Jones DL

No place like home: anatomy and function of the stem cell niche.

Nature reviews. Molecular cell biology

Jones DL, Wagers AJ

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

Science (New York, N.Y.)

Yamashita YM, Jones DL, Fuller MT

Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue.

Science (New York, N.Y.)

Kiger AA, Jones DL, Schulz C, Rogers MB, Fuller MT