
Professor
Orthopaedic Surgery
+1 415 476-0561
Hubert Kim, MD studies the modulation of secondary injury cascades and the application of stem cells to treat traumatic injuries, particularly in tissues that have poor intrinsic healing.
Publications
Defining Endogenous Mitochondrial Transfer in Muscle After Rotator Cuff Injury.
The American journal of sports medicine
Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes.
Stem cell research & therapy
The Role of Matrix Metalloproteinase-13 (MMP13) in TGF�/BMP Pathway Regulation of Fibro-Adipogenic Progenitor (FAP) Differentiation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Muscle-Derived Beige Adipose Precursors Secrete Promyogenic Exosomes That Treat Rotator Cuff Muscle Degeneration in Mice and Are Identified in Humans by Single-Cell RNA Sequencing.
The American journal of sports medicine
Rotator Cuff Tear Size Regulates Fibroadipogenic Progenitor Number and Gene Expression Profile in the Supraspinatus Independent of Patient Age.
The American journal of sports medicine
Microenergy acoustic pulses promotes muscle regeneration through in situ activation of muscle stem cells.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Preconditioning improves muscle regeneration after ischemia-reperfusion injury.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Rotator cuff tear degeneration and the role of fibro-adipogenic progenitors.
Annals of the New York Academy of Sciences
Beige FAPs Transplantation Improves Muscle Quality and Shoulder Function After Massive Rotator Cuff Tears.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Rotator Cuff Fibro-Adipogenic Progenitors Demonstrate Highest Concentration, Proliferative Capacity, and Adipogenic Potential Across Muscle Groups.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Beige fibro-adipogenic progenitor transplantation reduces muscle degeneration and improves function in a mouse model of delayed repair of rotator cuff tears.
Journal of shoulder and elbow surgery
Reversal of Fatty Infiltration After Suprascapular Nerve Compression Release Is Dependent on UCP1 Expression in Mice.
Clinical orthopaedics and related research
Knocking-out matrix metalloproteinase-13 exacerbates rotator cuff muscle fatty infiltration.
Muscles, ligaments and tendons journal
Lysophosphatidic acid-induced RhoA signaling and prolonged macrophage infiltration worsens fibrosis and fatty infiltration following rotator cuff tears.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Promoting Endochondral Bone Repair Using Human Osteoarthritic Articular Chondrocytes.
Tissue engineering. Part A
Costs and Complications of Short Versus Long Cephalomedullary Nailing of OTA 31-A2 Proximal Femur Fractures in U.S. Veterans.
Journal of orthopaedic trauma
Novel intracellular N-terminal truncated matrix metalloproteinase-2 isoform in skeletal muscle ischemia-reperfusion injury.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration.
Muscles, ligaments and tendons journal
Rat rotator cuff muscle responds differently from hindlimb muscle to a combined tendon-nerve injury.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Matrix metalloproteinase-2 plays a critical role in overload induced skeletal muscle hypertrophy.
Muscles, ligaments and tendons journal
Upregulation of transforming growth factor-� signaling in a rat model of rotator cuff tears.
Journal of shoulder and elbow surgery
Novel mouse model of spinal cord injury-induced heterotopic ossification.
Journal of rehabilitation research and development
Joint instability and cartilage compression in a mouse model of posttraumatic osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Differential ubiquitin-proteasome and autophagy signaling following rotator cuff tears and suprascapular nerve injury.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Trophic stimulation of articular chondrocytes by late-passage mesenchymal stem cells in coculture.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Original article Muscle extracellular matrix degradation and contractibility following tendon rupture and disuse.
Muscles, ligaments and tendons journal
Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy.
Journal of shoulder and elbow surgery
Cytotoxicity of local anesthetics on human mesenchymal stem cells.
The Journal of bone and joint surgery. American volume
mTOR regulates fatty infiltration through SREBP-1 and PPAR? after a combined massive rotator cuff tear and suprascapular nerve injury in rats.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Functional motor recovery after peripheral nerve repair with an aligned nanofiber tubular conduit in a rat model.
Regenerative medicine
MRI quantification of fatty infiltration and muscle atrophy in a mouse model of rotator cuff tears.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Fibroblast growth factor 2 enhances the kinetics of mesenchymal stem cell chondrogenesis.
Biochemical and biophysical research communications
Inducible immortality in hTERT-human mesenchymal stem cells.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Thermal stress potentiates bupivacaine chondrotoxicity.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
A mouse model of massive rotator cuff tears.
The Journal of bone and joint surgery. American volume
Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Muscle degeneration in rotator cuff tears.
Journal of shoulder and elbow surgery
Effects of local anesthetics on articular cartilage.
The American journal of sports medicine
Effects of mixing techniques on vancomycin-impregnated polymethylmethacrylate.
The Journal of arthroplasty
A rat model of massive rotator cuff tears.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy.
Biochemical and biophysical research communications
Chondrocyte apoptosis after simulated intraarticular fracture: a comparison of histologic detection methods.
Clinical orthopaedics and related research
Chondrocyte apoptosis: implications for osteochondral allograft transplantation.
Clinical orthopaedics and related research
Enhancing osteochondral allograft viability: effects of storage media composition.
Clinical orthopaedics and related research
Matrix metalloproteinase-2 expression and promoter/enhancer activity in skeletal muscle atrophy.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
A peek into the possible future of management of articular cartilage injuries: gene therapy and scaffolds for cartilage repair.
The Journal of orthopaedic and sports physical therapy
Chondrocyte apoptosis induced by hydrogen peroxide requires caspase activation but not mitochondrial pore transition.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Comparison of chondrocyte apoptosis in vivo and in vitro following acute osteochondral injury.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Chondrocyte apoptosis induced by collagen degradation: inhibition by caspase inhibitors and IGF-1.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society