
Professor
Biochemistry and Biophysics
+1 415 476-2699
Graeme Davis, PhD studies the cellular and molecular mechanisms of neuronal development and plasticity.
Publications
Activation and expansion of presynaptic signaling foci drives presynaptic homeostatic plasticity.
Neuron
SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.
Nature communications
Target-wide Induction and Synapse Type-Specific Robustness of Presynaptic Homeostasis.
Current biology : CB
Dystrobrevin is required postsynaptically for homeostatic potentiation at the Drosophila NMJ.
Biochimica et biophysica acta. Molecular basis of disease
A postsynaptic PI3K-cII dependent signaling controller for presynaptic homeostatic plasticity.
eLife
Engineering a light-activated caspase-3 for precise ablation of neurons in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Composition and Control of a Deg/ENaC Channel during Presynaptic Homeostatic Plasticity.
Cell reports
Homeostatic control of presynaptic neurotransmitter release.
Annual review of physiology
Archaerhodopsin voltage imaging: synaptic calcium and BK channels stabilize action potential repolarization at the Drosophila neuromuscular junction.
The Journal of neuroscience : the official journal of the Society for Neuroscience
RIM controls homeostatic plasticity through modulation of the readily-releasable vesicle pool.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Snapin is critical for presynaptic homeostatic plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Transsynaptic control of presynaptic Ca�? influx achieves homeostatic potentiation of neurotransmitter release.
Current biology : CB
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release.
Science (New York, N.Y.)
Stathmin is required for stability of the Drosophila neuromuscular junction.
The Journal of neuroscience : the official journal of the Society for Neuroscience
S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development.
The Journal of cell biology
Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle release.
Neuron
Vesicle priming in a SNAP.
Neuron
Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog.
The Journal of neuroscience : the official journal of the Society for Neuroscience
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis.
Science (New York, N.Y.)
Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton.
The Journal of cell biology
Formin-dependent synaptic growth: evidence that Dlar signals via Diaphanous to modulate synaptic actin and dynamic pioneer microtubules.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Clathrin dependence of synaptic-vesicle formation at the Drosophila neuromuscular junction.
Current biology : CB
A postsynaptic spectrin scaffold defines active zone size, spacing, and efficacy at the Drosophila neuromuscular junction.
The Journal of cell biology
Homeostatic control of neural activity: from phenomenology to molecular design.
Annual review of neuroscience
Presynaptic spectrin is essential for synapse stabilization.
Current biology : CB
Mobilization and fusion of a non-recycling pool of synaptic vesicles under conditions of endocytic blockade.
Neuropharmacology
Coordinating structural and functional synapse development: postsynaptic p21-activated kinase independently specifies glutamate receptor abundance and postsynaptic morphology.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Controlling the active properties of excitable cells.
Current opinion in neurobiology
Synapse disassembly.
Genes & development
Homeostatic control of presynaptic release is triggered by postsynaptic membrane depolarization.
Neuron
Synapse formation revisited.
Nature neuroscience
Maintaining the stability of neural function: a homeostatic hypothesis.
Annual review of physiology
Genetic analysis of synaptic development and plasticity: homeostatic regulation of synaptic efficacy.
Current opinion in neurobiology
The many faces of fasciclin II: Genetic analysis reveals multiple roles for a cell adhesion molecule during the generation of neuronal specificity.
Cold Spring Harbor symposia on quantitative biology
A neural tetraspanin, encoded by late bloomer, that facilitates synapse formation.
Science (New York, N.Y.)
Long-term regulation of short-term plasticity: a postsynaptic influence on presynaptic transmitter release.
Journal of physiology, Paris
Retrograde signaling and the development of transmitter release properties in the invertebrate nervous system.
Journal of neurobiology
Long-term regulation of short-term transmitter release properties: retrograde signaling and synaptic development.
Trends in neurosciences
A role for postsynaptic neurons in determining presynaptic release properties in the cricket CNS: evidence for retrograde control of facilitation.
The Journal of neuroscience : the official journal of the Society for Neuroscience