Assistant Professor
Cell and Tissue Biology
Erica Hutchins, PhD studies how post-transcriptional regulation controls developmental pluripotency and cell fate decisions in vivo, using vertebrate neural crest as a model.
Publications
CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos.
Developmental biology
CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos.
bioRxiv : the preprint server for biology
Post-transcriptional regulation as a conserved driver of neural crest and cancer-cell migration.
Current opinion in cell biology
"Beyond transcription: How post-transcriptional mechanisms drive neural crest EMT".
Genesis (New York, N.Y. : 2000)
Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition.
Proceedings of the National Academy of Sciences of the United States of America
RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification.
eLife
Essential function and targets of BMP signaling during midbrain neural crest delamination.
Developmental biology
Transcriptomic Identification of Draxin-Responsive Targets During Cranial Neural Crest EMT.
Frontiers in physiology
A Spectrum of Cell States During the Epithelial-to-Mesenchymal Transition.
Methods in molecular biology (Clifton, N.J.)
Draxin alters laminin organization during basement membrane remodeling to control cranial neural crest EMT.
Developmental biology
Draxin acts as a molecular rheostat of canonical Wnt signaling to control cranial neural crest EMT.
The Journal of cell biology
Migration and diversification of the vagal neural crest.
Developmental biology
A novel role for the nuclear localization signal in regulating hnRNP K protein stability in vivo.
Biochemical and biophysical research communications
c-Jun N-terminal kinase phosphorylation of heterogeneous nuclear ribonucleoprotein K regulates vertebrate axon outgrowth via a posttranscriptional mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience