Erica Hutchins, PhD

Assistant Professor

Cell and Tissue Biology

Erica Hutchins, PhD studies how post-transcriptional regulation controls developmental pluripotency and cell fate decisions in vivo, using vertebrate neural crest as a model.

Publications

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis.

Nature communications

Williams J, Camarda R, Malkov S, Zimmerman LJ, Manning S, Aran D, Beardsley A, Van de Mark D, Nakagawa R, Chen Y, Berdan C, Louie SM, Mahieu C, Superville D, Winkler J, Willey E, Hutchins EJ, Gagnon JD, Avsaroglu SK, Shinoda K, Gruner M, Nishida H, Ansel KM, Werb Z, Nomura DK, Kajimura S, Butte AJ, Sanders ME, Liebler DC, Rugo HS, Krings G, Shepherd JA, Goga A

Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition.

Proceedings of the National Academy of Sciences of the United States of America

Piacentino ML, Hutchins EJ, Andrews CJ, Bronner ME

Phosphorylation of heterogeneous nuclear ribonucleoprotein K at an extracellular signal-regulated kinase phosphorylation site promotes neurofilament-medium protein expression and axon outgrowth in Xenopus.

Neuroscience letters

Hutchins EJ, Belrose JL, Szaro BG

c-Jun N-terminal kinase phosphorylation of heterogeneous nuclear ribonucleoprotein K regulates vertebrate axon outgrowth via a posttranscriptional mechanism.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Hutchins EJ, Szaro BG

Publications

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis.

Characterization of Pumilio gene expression during early neural crest development.

CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos.

CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos.

Post-transcriptional regulation as a conserved driver of neural crest and cancer-cell migration.

"Beyond transcription: How post-transcriptional mechanisms drive neural crest EMT".

Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition.

RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification.

Essential function and targets of BMP signaling during midbrain neural crest delamination.

Transcriptomic Identification of Draxin-Responsive Targets During Cranial Neural Crest EMT.

A Spectrum of Cell States During the Epithelial-to-Mesenchymal Transition.

Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration.

Draxin alters laminin organization during basement membrane remodeling to control cranial neural crest EMT.

Draxin acts as a molecular rheostat of canonical Wnt signaling to control cranial neural crest EMT.

Migration and diversification of the vagal neural crest.

A novel role for the nuclear localization signal in regulating hnRNP K protein stability in vivo.

Phosphorylation of heterogeneous nuclear ribonucleoprotein K at an extracellular signal-regulated kinase phosphorylation site promotes neurofilament-medium protein expression and axon outgrowth in Xenopus.

c-Jun N-terminal kinase phosphorylation of heterogeneous nuclear ribonucleoprotein K regulates vertebrate axon outgrowth via a posttranscriptional mechanism.