Corey Harwell, PhD

Associate Professor
Neurology
[email protected]
+1 415 476-0768

Corey Harwell, PhD studies cellular and molecular programs that regulate neural cell fate and circuit assembly in the developing brain.

Publications: 

Conservation, alteration, and redistribution of mammalian striatal interneurons.

bioRxiv : the preprint server for biology

Corrigan EK, DeBerardine M, Poddar A, Turrero García M, Schmitz MT, Harwell CC, Paredes MF, Krienen FM, Pollen AA

PRDM16 co-operates with LHX2 to shape the human brain.

Oxford open neuroscience

Suresh V, Bhattacharya B, Tshuva RY, Danan Gotthold M, Olender T, Bose M, Pradhan SJ, Zeev BB, Smith RS, Tole S, Galande S, Harwell CC, Baizabal JM, Reiner O

Astrocyte Development in the Rodent.

Advances in neurobiology

Xie Y, Harwell CC, Garcia ADR

Developmental origin and local signals cooperate to determine septal astrocyte identity.

bioRxiv : the preprint server for biology

Xie Y, Reid CM, Granados AA, Garcia MT, Dale-Huang F, Hanson SM, Mancia W, Liu J, Adam M, Mosto O, Pisco AO, Alvarez-Buylla A, Harwell CC

A developmentally defined population of neurons in the lateral septum controls responses to aversive stimuli.

bioRxiv : the preprint server for biology

García MT, Tran DN, Peterson RE, Stegmann SK, Hanson SM, Reid CM, Xie Y, Vu S, Harwell CC

PRDM16 co-operates with LHX2 to shape the human brain.

bioRxiv : the preprint server for biology

Suresh V, Bhattacharya B, Tshuva RY, Danan Gotthold M, Olender T, Bose M, Pradhan SJ, Ben Zeev B, Smith RS, Tole S, Galande S, Harwell C, Baizabal JM, Reiner O

Astrocytes as master modulators of neural networks: Synaptic functions and disease-associated dysfunction of astrocytes.

Annals of the New York Academy of Sciences

Stogsdill JA, Harwell CC, Goldman SA

Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis.

The EMBO journal

Mukhtar T, Breda J, Adam MA, Boareto M, Grobecker P, Karimaddini Z, Grison A, Eschbach K, Chandrasekhar R, Vermeul S, Okoniewski M, Pachkov M, Harwell CC, Atanasoski S, Beisel C, Iber D, van Nimwegen E, Taylor V

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.

Cell reports

Xie Y, Kuan AT, Wang W, Herbert ZT, Mosto O, Olukoya O, Adam M, Vu S, Kim M, Tran D, Gómez N, Charpentier C, Sorour I, Lacey TE, Tolstorukov MY, Sabatini BL, Lee WA, Harwell CC

Transcriptional profiling of sequentially generated septal neuron fates.

eLife

Turrero Garc?a M, Stegmann SK, Lacey TE, Reid CM, Hrvatin S, Weinreb C, Adam MA, Nagy MA, Harwell CC

The Eya1 Phosphatase Mediates Shh-Driven Symmetric Cell Division of Cerebellar Granule Cell Precursors.

Developmental neuroscience

Merk DJ, Zhou P, Cohen SM, Pazyra-Murphy MF, Hwang GH, Rehm KJ, Alfaro J, Reid CM, Zhao X, Park E, Xu PX, Chan JA, Eck MJ, Nazemi KJ, Harwell CC, Segal RA

Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production.

Development (Cambridge, England)

Turrero Garc?a M, Baizabal JM, Tran DN, Peixoto R, Wang W, Xie Y, Adam MA, English LA, Reid CM, Brito SI, Booker MA, Tolstorukov MY, Harwell CC

Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.

eLife

Granger AJ, Wang W, Robertson K, El-Rifai M, Zanello AF, Bistrong K, Saunders A, Chow BW, Nu?ez V, Turrero Garc?a M, Harwell CC, Gu C, Sabatini BL

Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization.

eLife

Hill SA, Blaeser AS, Coley AA, Xie Y, Shepard KA, Harwell CC, Gao WJ, Garcia ADR

The Elegance of Sonic Hedgehog: Emerging Novel Functions for a Classic Morphogen.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Garcia ADR, Han YG, Triplett JW, Farmer WT, Harwell CC, Ihrie RA

The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.

Neuron

Baizabal JM, Mistry M, Garc?a MT, G?mez N, Olukoya O, Tran D, Johnson MB, Walsh CA, Harwell CC

The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.

Neuron

Baizabal JM, Mistry M, Garc?a MT, G?mez N, Olukoya O, Tran D, Johnson MB, Walsh CA, Harwell CC

Radial glia in the ventral telencephalon.

FEBS letters

Turrero Garc?a M, Harwell CC

Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons.

Neuron

Harwell CC, Fuentealba LC, Gonzalez-Cerrillo A, Parker PR, Gertz CC, Mazzola E, Garcia MT, Alvarez-Buylla A, Cepko CL, Kriegstein AR

Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation.

Neuron

Harwell CC, Parker PR, Gee SM, Okada A, McConnell SK, Kreitzer AC, Kriegstein AR

Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.

Neuron

Ihrie RA, Shah JK, Harwell CC, Levine JH, Guinto CD, Lezameta M, Kriegstein AR, Alvarez-Buylla A