Assistant Professor
Pathology
Carolyn Sangokoya MD, PhD is a physician-scientist, RNA biologist, and liver pathologist studying RNA and metabolic networks driving cell fate, function, and plasticity. Her lab builds and uses molecular tools to evaluate, re-engineer, and re-wire cell fates for targeted plasticity and regenerative medicine.
Publications
Multimodal Spatial Transcriptomics Reveals the Developing Human Liver Niche at Single-Cell Resolution.
Gastro hep advances
Coordinate post-transcriptional regulation by microRNAs and RNA binding proteins is critical for early embryonic cell fate decisions.
bioRxiv : the preprint server for biology
The genetically encoded biosensor FEOX is a molecular gauge for cellular iron environment dynamics at single cell resolution.
Scientific reports
The FIRE biosensor illuminates iron regulatory protein activity and cellular iron homeostasis.
Cell reports methods
Measuring Endocytosis and Endosomal Uptake at Single Cell Resolution.
Methods in molecular biology (Clifton, N.J.)
MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis.
Proceedings of the National Academy of Sciences of the United States of America
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress.
Cancer & metabolism
Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin.
PLoS genetics
Isolation and characterization of microRNAs of human mature erythrocytes.
Methods in molecular biology (Clifton, N.J.)
Look to behavioral economics.
Health affairs (Project Hope)