
Associate Professor
Medicine
+1 415 476-6160
Bruce Wang, MD studies the cellular and molecular mechanisms that regulate liver development, homeostasis and regeneration.
Publications
Liver involvement in a large cohort of patients with erythropoietic protoporphyria or X-linked protoporphyria.
Hepatology communications
AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion.
Nature biotechnology
Reducing diagnostic delays in acute hepatic porphyria using health records data and machine learning.
Journal of the American Medical Informatics Association : JAMIA
Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study.
Orphanet journal of rare diseases
Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors.
bioRxiv : the preprint server for biology
An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome.
Nature communications
Liver transplantation and primary liver cancer in porphyria.
Liver international : official journal of the International Association for the Study of the Liver
Reducing diagnostic delays in Acute Hepatic Porphyria using electronic health records data and machine learning: a multicenter development and validation study.
medRxiv : the preprint server for health sciences
Evidence-based consensus guidelines for the diagnosis and management of protoporphyria-related liver dysfunction in erythropoietic protoporphyria and X-linked protoporphyria.
Hepatology (Baltimore, Md.)
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review.
Gastroenterology
Concordance of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing.
Life science alliance
A pilot study of oral iron therapy in erythropoietic protoporphyria and X-linked protoporphyria.
Molecular genetics and metabolism reports
Rare, Overlooked, or Underappreciated Causes of Recurrent Abdominal Pain: A Primer for Gastroenterologists.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.
Nature genetics
Evidence-based consensus guidelines for the diagnosis and management of erythropoietic protoporphyria and X-linked protoporphyria.
Journal of the American Academy of Dermatology
Disease burden in patients with acute hepatic porphyria: experience from the phase 3 ENVISION study.
Orphanet journal of rare diseases
Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.
Nature communications
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
Science (New York, N.Y.)
Cell types of origin of the cell-free transcriptome.
Nature biotechnology
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states.
Nature communications
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells.
Nature cell biology
Novel treatment options for acute hepatic porphyrias.
Current opinion in gastroenterology
The acute hepatic porphyrias.
Translational gastroenterology and hepatology
TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
Journal of hepatology
Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium.
Hepatology (Baltimore, Md.)
Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria.
Genetics in medicine : official journal of the American College of Medical Genetics
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
The New England journal of medicine
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Scientific reports
mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy.
The American journal of pathology
Evaluating the Patient-Reported Outcomes Measurement Information System scales in acute intermittent porphyria.
Genetics in medicine : official journal of the American College of Medical Genetics
Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice.
Hepatology (Baltimore, Md.)
Tissue Repair in the Mouse Liver Following Acute Carbon Tetrachloride Depends on Injury-Induced Wnt/β-Catenin Signaling.
Hepatology (Baltimore, Md.)
Acute Hepatic Porphyrias: Review and Recent Progress.
Hepatology communications
Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture.
Cell
Acute hepatic porphyrias: Recommendations for evaluation and long-term management.
Hepatology (Baltimore, Md.)
Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria.
JAMA dermatology
Pitfalls in Erythrocyte Protoporphyrin Measurement for Diagnosis and Monitoring of Protoporphyrias.
Clinical chemistry
Acute Hepatic Porphyria.
Journal of clinical and translational hepatology
Acute liver failure with thyrotoxicosis treated with liver transplantation.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.
The Journal of clinical investigation
Role of alphavbeta6 integrin in acute biliary fibrosis.
Hepatology (Baltimore, Md.)
Six decades of progress and change in hospital medicine, 1947-2007.
The Pharos of Alpha Omega Alpha-Honor Medical Society. Alpha Omega Alpha
TWEAK induces liver progenitor cell proliferation.
The Journal of clinical investigation
Hereditary Coproporphyria
GeneReviews®