
Professor
Pediatrics
+1 415 502-4430
James Rubenstein, MD, PhD is working to define the molecular features of non-Hodgkin's lymphoma of the central nervous system using microarray technology.
Publications
Identification of Genomic Biomarkers of Disease Progression and Survival in Primary CNS Lymphoma.
Blood advances
Clinicopathologic features of primary central nervous system anaplastic large cell lymphoma: a multicenter study identifies age and ALK status as prognostic factors.
Journal of hematopathology
Myeloablative Vs. Non-Myeloablative Consolidation for Primary Central Nervous System Lymphoma: Results of Alliance 51101.
Blood advances
Utility of PD-1, PD-L1, and IDO-1 Stains in Ocular Extranodal Marginal Zone Lymphoma (MZL) and Diffuse Large B-cell Lymphoma (DLBCL).
Applied immunohistochemistry & molecular morphology : AIMM
Liquid biopsy for improving diagnosis and monitoring of CNS lymphomas: a RANO review.
Neuro-oncology
Molecular profiling identifies at least 3 distinct types of posttransplant lymphoproliferative disorder involving the CNS.
Blood advances
BTK Degradation as a Novel Therapeutic Strategy in Relapsed CNS Lymphoma: Proof of Concept Studies in Intracranial Preclinical including Patient-Derived Models.
Hematological oncology
IDENTIFICATION OF GENOMIC BIOMARKERS OF DISEASE PROGRESSION AND SURVIVAL IN NEWLY-DIAGNOSED PRIMARY CNS LYMPHOMA.
Hematological oncology
Older patients with primary central nervous system lymphoma: Survival and prognostication across 20 U.S. cancer centers.
American journal of hematology
EBV-positive PCNSL in older patients: incidence, characteristics, tumor pathology, and outcomes across a large multicenter cohort.
Leukemia & lymphoma
Tafasitamab at the blood-brain barrier.
British journal of haematology
Primary CNS lymphoma: update on molecular pathogenesis and therapy.
Leukemia & lymphoma
Primary CNS Lymphoma: Progress With Dose-Intensive Consolidation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
A genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome.
Blood advances
Tumor metabolism and neurocognition in CNS lymphoma.
Neuro-oncology
Primary central nervous system lymphoma in older adults and the rationale for maintenance strategies: a narrative review.
Annals of lymphoma
A functional mammalian display screen identifies rare antibodies that stimulate NK cell-mediated cytotoxicity.
Proceedings of the National Academy of Sciences of the United States of America
Myeloablative versus non-myeloablative consolidative chemotherapy for newly diagnosed primary central nervous system lymphoma: Results of CALGB 51101 (Alliance).
Journal of Clinical Oncology
Blood Coagulation Factor Fibrinogen in Tumor Pathogenesis of Central Nervous System B-Cell Lymphoma.
The American journal of pathology
On point in primary CNS lymphoma.
Hematological oncology
Cutaneous T-Cell Lymphoma PDX Drug Screening Platform Identifies Cooperation between Inhibitions of PI3Kα/δ and HDAC.
The Journal of investigative dermatology
Myeloablative versus non-myeloablative consolidative chemotherapy for newly diagnosed primary central nervous system lymphoma: Results of induction therapy in Alliance 51101.
Journal of Clinical Oncology
THERAPEUTIC VITRECTOMY AS AN ADJUNCT TREATMENT TO SYSTEMIC CHEMOTHERAPY FOR INTRAOCULAR LYMPHOMA.
Retinal cases & brief reports
Maintenance lenalidomide in primary CNS lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology
An audit of retinal lymphoma treatment at the University of California San Francisco.
Eye (London, England)
Evolving Treatments for Primary Central Nervous System Lymphoma.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Comprehensive approach to diagnosis and treatment of newly diagnosed primary CNS lymphoma.
Neuro-oncology
Low-dose lenalidomide maintenance after induction therapy in older patients with primary central nervous system lymphoma.
British journal of haematology
Can rituximab unlock the innate potential of checkpoint blockade in the CNS?
Leukemia & lymphoma
Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma.
Blood advances
Insights from a Case of Vitreoretinal Lymphoma.
Ocular oncology and pathology
Biology of CNS lymphoma and the potential of novel agents.
Hematology. American Society of Hematology. Education Program
EXTH-71. HYPERPOLARIZED [1-13C] PYRUVATE AS A BIOMARKER FOR TREATMENT MONITORING IN LYMPHOMA MURINE MODELS.
Neuro-oncology
CHECKMATE 647: A PHASE 2, OPEN-LABEL STUDY OF NIVOLUMAB IN RELAPSED/REFRACTORY PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA OR RELAPSED/REFRACTORY PRIMARY TESTICULAR LYMPHOMA.
Hematological oncology
Preliminary analysis of lenalidomide maintenance after methotrexate-temozolomide-rituximab induction in older patients with PCNSL.
Hematological oncology
Regression of methotrexate-resistant AIDS-related primary central nervous system lymphoma with lenalidomide plus combination anti-retroviral therapy.
Leukemia & lymphoma
The Challenge of Primary Central Nervous System Lymphoma.
Hematology/oncology clinics of North America
ATIM-27. PHASE I INVESTIGATION OF LENALIDOMIDE PLUS RITUXIMAB AND OUTCOMES OF LENALIDOMIDE MAINTENANCE IN RECURRENT CNS LYMPHOMA.
Neuro-oncology
Abstract A06: Development of a drug discovery platform using clinically relevant patient-derived xenograft models for cutaneous T cell lymphomas.
Clinical Cancer Research
Phase I investigation of lenalidomide plus rituximab and outcomes of lenalidomide maintenance in recurrent CNS lymphoma.
Journal of Clinical Oncology
Therapy for Secondary CNS Involvement in Malignant Lymphomas: No Standard Yet!
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Performance of Apparent Diffusion Coefficient Values and Conventional MRI Features in Differentiating Tumefactive Demyelinating Lesions From Primary Brain Neoplasms.
AJR. American journal of roentgenology
Prolonged Complete Response in a Pediatric Patient With Primary Peripheral T-Cell Lymphoma of the Central Nervous System.
Pediatric hematology and oncology
New approaches in primary central nervous system lymphoma.
Chinese clinical oncology
77-year-old woman with a dural-based mass. Marginal zone B-cell lymphoma (MZBCL).
Brain pathology (Zurich, Switzerland)
Progress in central nervous system lymphomas.
British journal of haematology
Reply to M.C. Chamberlain.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
CNS Lymphoma.
Rare Lymphomas
Complement activation and intraventricular rituximab distribution in recurrent central nervous system lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
The roles of tumor associated macrophages and interferon gamma in immune surveillance in CNS lymphoma (P2211).
The Journal of Immunology
Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
Clinical cancer research : an official journal of the American Association for Cancer Research
Biology of Primary Central Nervous System Lymphoma.
Lymphoma and Leukemia of the Nervous System
Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium.
The oncologist
Regression of refractory intraocular large B-cell lymphoma with lenalidomide monotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Interim results of a phase I trial of intraventricular rituximab plus methotrexate in recurrent CNS lymphoma: Macrophage polarization and acquired resistance to therapy.
Journal of Clinical Oncology
Abstract 2728: Multivariate analysis of cerebrospinal fluid protein biomarkers in central nervous system lymphoma patients and controls.
Clinical Research
Abstract 5580: Macrophage polarization and acquired resistance to rituximab in CNS lymphoma.
Clinical Research
Biology and treatment of primary central nervous system lymphoma.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Reply to H. Zetterberg et al.
Journal of Clinical Oncology
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
Clinical cancer research : an official journal of the American Association for Cancer Research
Insights into the biology of primary central nervous system lymphoma.
Current oncology reports
Sarcoidosis of the pineal gland: an unusual presentation of neurosarcoidosis.
Journal of neuro-oncology
Chapter 56 Brain Metastases and Neoplastic Meningitis.
Abeloff\u0027s Clinical Oncology
Primary lymphoma of the central nervous system: epidemiology, pathology and current approaches to diagnosis, prognosis and treatment.
Leukemia & lymphoma
Protein biomarker identification in the CSF of patients with CNS lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
In Reply.
Journal of Clinical Oncology
Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Molecular pathogenesis of primary central nervous system lymphoma.
Neurosurgical focus
Treatment of primary CNS lymphoma with induction high-dose methotrexate, temozolomide, rituximab followed by consolidation cytarabine/etoposide: A pilot study with biomarker analysis.
Journal of Clinical Oncology
Surgically (laparotomy/laparoscopy) guided placement of high dose rate interstitial irradiation catheters (LG-HDRT): technique and outcome.
Gynecologic oncology
Pathology and genetics of primary central nervous system and intraocular lymphoma.
Hematology/oncology clinics of North America
Primary CNS lymphoma of T-cell origin: a descriptive analysis from the international primary CNS lymphoma collaborative group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Results from a phase I study of intraventricular administration of rituximab in patients with recurrent lymphomatous meningitis.
Journal of Clinical Oncology
Results from a phase I study of intraventricular administration of rituximab in patients with recurrent lymphomatous meningitis.
Journal of Clinical Oncology
Brain Metastases from Genitourinary Cancer: Germ Cell, Testicular, Prostate and Bladder Cancer.
Intracranial Metastases
Hemorrhage and VEGF expression in a case of primary CNS lymphoma.
Journal of neuro-oncology
Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions.
Science (New York, N.Y.)
Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption.
Neoplasia (New York, N.Y.)
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.
Development (Cambridge, England)
Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells.
Development (Cambridge, England)