
Assistant Professor
Pediatrics
Serine Avagyan, MD, PhD studies blood stem cell clonality and clonal hematopoiesis.
Publications
KIT Inhibitor Therapy in a Pediatric Patient With Systemic Mastocytosis and a Germ Cell Tumor of Shared Clonal Origin.
Pediatric blood & cancer
High Melphalan Exposure Increases the Risk of Graft-versus-Host Disease in Pediatric Patients Undergoing Alpha-Beta T-Cell Depleted Haploidentical Transplantation.
Transplantation and cellular therapy
Younger Children with Non-Malignant Disease Have Increased Incidence of Mixed Myeloid Chimerism After Allogeneic Hematopoietic Cell Transplantation with Busulfan-Based Conditioning.
Transplantation and cellular therapy
Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis.
bioRxiv : the preprint server for biology
Hematopoietic stem cell division is governed by distinct RUNX1 binding partners.
bioRxiv : the preprint server for biology
Editorial: Biological aspects of bone marrow failure.
Frontiers in oncology
Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C.
Cell reports
Clonal hematopoiesis and inflammation - the perpetual cycle.
Trends in cell biology
Lessons From Pediatric MDS: Approaches to Germline Predisposition to Hematologic Malignancies.
Frontiers in oncology
Resistance to inflammation underlies enhanced fitness in clonal hematopoiesis.
Science (New York, N.Y.)
To T or not to B: germline RUNX1 mutation preferences in pediatric ALL predisposition.
The Journal of clinical investigation
Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages.
Blood advances
Comparison of Outcomes of Myeloablative Allogeneic Stem Cell Transplantation for Pediatric Patients with Bone Marrow Failure, Myelodysplastic Syndrome and Acute Myeloid Leukemia with and without Germline GATA2 Mutations.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors.
Zebrafish
Understanding the regulation of vertebrate hematopoiesis and blood disorders - big lessons from a small fish.
FEBS letters
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Molecular cell
Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis.
Human gene therapy
Propranolol as a first-line treatment for diffuse infantile hepatic hemangioendothelioma.
Journal of pediatric gastroenterology and nutrition
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.
Science (New York, N.Y.)
A quantitative trait locus on chr.4 regulates thymic involution.
The journals of gerontology. Series A, Biological sciences and medical sciences
Identification and in vivo analysis of murine hematopoietic stem cells.
Methods in enzymology
A quantitative trait locus on chromosome 4 affects cycling of hematopoietic stem and progenitor cells through regulation of TGF-beta 2 responsiveness.
Journal of immunology (Baltimore, Md. : 1950)
Test of Cairns-Smith's 'crystals-as-genes' hypothesis.
Faraday discussions
Immunokinetics of autoreactive CD4 T cells in blood: a reporter for the "hit-and-run" autoimmune attack on pancreas and diabetes progression.
Journal of autoimmunity
Selection footprint in the FimH adhesin shows pathoadaptive niche differentiation in Escherichia coli.
Molecular biology and evolution