
Professor
Biochemistry and Biophysics
+1 415 514-0448
Barbara Panning, PhD studies how RNA containing complexes modulate chromatin structure and gene expression.
Publications
O-GlcNAc modifications regulate lamin A tail processing.
bioRxiv : the preprint server for biology
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate.
bioRxiv : the preprint server for biology
X Chromosome Factor Kdm6a Enhances Cognition Independent of Its Demethylase Function in the Aging XY Male Brain.
The journals of gerontology. Series A, Biological sciences and medical sciences
A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease.
Science translational medicine
Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program.
Proceedings of the National Academy of Sciences of the United States of America
Activators and repressors: A balancing act for X-inactivation.
Seminars in cell & developmental biology
Editorial overview: Genome architecture and expression.
Current opinion in genetics & development
Quantitatively imaging chromosomes by correlated cryo-fluorescence and soft x-ray tomographies.
Biophysical journal
X-inactivation: Xist RNA uses chromosome contacts to coat the X.
Current biology : CB
The Topological Organization of the Inactive X Chromosome in its Native State.
Biophysical journal
The imprinted polycomb group gene Sfmbt2 is required for trophoblast maintenance and placenta development.
Development (Cambridge, England)
Quantitative genetic-interaction mapping in mammalian cells.
Nature methods
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells.
Cell stem cell
Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Control of embryonic stem cell identity by nucleosome remodeling enzymes.
Current opinion in genetics & development
The A-repeat links ASF/SF2-dependent Xist RNA processing with random choice during X inactivation.
Nature structural & molecular biology
Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells.
The Journal of cell biology
High resolution electron transfer dissociation studies of unfractionated intact histones from murine embryonic stem cells using on-line capillary LC separation: determination of abundant histone isoforms and post-translational modifications.
Molecular & cellular proteomics : MCP
Fine-tuning silencing.
Cell stem cell
The zinc finger protein Zn72D and DEAD box helicase Belle interact and control maleless mRNA and protein levels.
BMC molecular biology
Chromatin regulation Tip(60)s the balance in embryonic stem cell self-renewal.
Cell cycle (Georgetown, Tex.)
X-chromosome inactivation: the molecular basis of silencing.
Journal of biology
Epigenomics: a roadmap, but to where?
Science (New York, N.Y.)
Transcriptional regulation: it takes a village.
Molecular cell
The colocalization transition of homologous chromosomes at meiosis.
Physical review. E, Statistical, nonlinear, and soft matter physics
X-inactivation: it takes two to count.
Current biology : CB
IRE1 signaling affects cell fate during the unfolded protein response.
Science (New York, N.Y.)
Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed.
The Journal of cell biology
Zinc finger protein Zn72D promotes productive splicing of the maleless transcript.
Molecular and cellular biology
The histone domain of macroH2A1 contains several dispersed elements that are each sufficient to direct enrichment on the inactive X chromosome.
Journal of molecular biology
The polycomb group protein SUZ12 regulates histone H3 lysine 9 methylation and HP1 alpha distribution.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology
Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome.
The Journal of biological chemistry
Mapping post-translational modifications of the histone variant macroH2A1 using tandem mass spectrometry.
The FASEB Journal
The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation.
Nature cell biology
Counting chromosomes: not as easy as 1, 2, 3.
Current biology : CB
Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry.
Molecular & cellular proteomics : MCP
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.
Proceedings of the National Academy of Sciences of the United States of America
Recognition and modification of seX chromosomes.
Current opinion in genetics & development
Chromatin modifications on the inactive X chromosome.
Progress in molecular and subcellular biology
Chromatin remodeling in dosage compensation.
Annual review of genetics
Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome.
The Journal of cell biology
MACRO-H2A: A STRUCTURALLY AND FUNCTIONALLY DIVERSE HISTONE VARIANT.
Cold Spring Harbor symposia on quantitative biology
X inactivation in mouse ES cells: histone modifications and FISH.
Methods in enzymology
Epigenetic gene regulation by noncoding RNAs.
Current opinion in cell biology
Epigenetic gene regulation by noncoding RNAs.
Current opinion in cell biology
Role of histone H3 lysine 27 methylation in X inactivation.
Science (New York, N.Y.)
Xist RNA and the mechanism of X chromosome inactivation.
Annual review of genetics
Identification of an autoimmune serum containing antibodies against the Barr body.
Proceedings of the National Academy of Sciences of the United States of America
X inactivation: Tsix and Xist as yin and yang.
Current biology : CB
Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing.
Nucleic acids research
Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation.
Nature genetics
Mammalian X chromosome inactivation.
Novartis Foundation symposium
Herpes simplex virus immediate-early proteins ICP0 and ICP4 activate the endogenous human alpha-globin gene in nonerythroid cells.
Journal of virology
Xist-deficient mice are defective in dosage compensation but not spermatogenesis.
Genes & development
DNA hypomethylation can activate Xist expression and silence X-linked genes.
Genes & development
Activation of expression of multiple subfamilies of human Alu elements by adenovirus type 5 and herpes simplex virus type 1.
Journal of molecular biology
Activation of RNA polymerase III transcription of human Alu elements by herpes simplex virus.
Virology
Activation of RNA polymerase III transcription of human Alu repetitive elements by adenovirus type 5: requirement for the E1b 58-kilodalton protein and the products of E4 open reading frames 3 and 6.
Molecular and cellular biology
Regulation of cellular genes transduced by herpes simplex virus.
Journal of virology