Aras Mattis, MD, PhD

Sbierski-Kind J, Cautivo KM, Wagner JC, Dahlgren MW, Nilsson J, Krasilnikov M, Mroz NM, Lizama CO, Gan AL, Matatia PR, Taruselli MT, Chang AA, Caryotakis S, O'Leary CE, Kotas M, Mattis AN, Peng T, Locksley RM, Molofsky AB

Metastatic colorectal adenocarcinoma tumor purity assessment from whole exome sequencing data.

PloS one

Tbeileh N, Timmerman L, Mattis AN, Toriguchi K, Kasai Y, Corvera C, Nakakura E, Hirose K, Donner DB, Warren RS, Karelehto E

DNA content abnormality frequently develops in the right/proximal colon in patients with primary sclerosing cholangitis and inflammatory bowel disease and is highly predictive of subsequent detection of dysplasia.

Histopathology

Zhang R, Rabinovitch PS, Mattis AN, Lauwers GY, Choi WT

Self-Assembled Matrigel-Free iPSC-Derived Liver Organoids Demonstrate Wide-Ranging Highly Differentiated Liver Functions.

Stem cells (Dayton, Ohio)

Weng Y, Han S, Sekyi MT, Su T, Mattis AN, Chang TT

Fundic Gland Polyps Lack DNA Content Abnormality Characteristic of Other Adenomatous Precursor Lesions in the Gastrointestinal Tract.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Akanuma N, Rabinovitch PS, Mattis AN, Lauwers GY, Choi WT

Transient expression of factor VIII and a chronic high-fat diet induces ER stress and late hepatocyte oncogenesis.

Molecular therapy : the journal of the American Society of Gene Therapy

Pierce GF, Mattis AN

Targeting acid ceramidase ameliorates fibrosis in mouse models of non-alcoholic steatohepatitis.

Frontiers in medicine

Yu A, Cable C, Sharma S, Shihan MH, Mattis AN, Mileva I, Hannun YA, Duwaerts CC, Chen JY

Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease.

Cellular and molecular gastroenterology and hepatology

Muñoz A, Theusch E, Kuang YL, Nalula G, Peaslee C, Dorlhiac G, Landry MP, Streets A, Krauss RM, Iribarren C, Mattis AN, Medina MW

Clinical Application of Induced Hepatocyte-like Cells Produced from Mesenchymal Stromal Cells: A Literature Review.

Cells

Bogliotti Y, Vander Roest M, Mattis AN, Gish RG, Peltz G, Anwyl R, Kivlighn S, Schuur ER

Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A.

Nature medicine

Fong S, Yates B, Sihn CR, Mattis AN, Mitchell N, Liu S, Russell CB, Kim B, Lawal A, Rangarajan S, Lester W, Bunting S, Pierce GF, Pasi KJ, Wong WY

Nonampullary Duodenal Adenomas in Familial Adenomatous Polyposis and Sporadic Patients Lack the DNA Content Abnormality That Is Characteristic of the Adenoma-Carcinoma Sequence Involved in the Development of Other Gastrointestinal Malignancies.

The American journal of surgical pathology

Mohammed N, Rabinovitch PS, Wang D, Kovári BP, Mattis AN, Lauwers GY, Choi WT

Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation.

Hepatology (Baltimore, Md.)

Peaslee C, Esteva-Font C, Su T, Munoz-Howell A, Duwaerts CC, Liu Z, Rao S, Liu K, Medina M, Sneddon JB, Maher JJ, Mattis AN

Gastric Intestinal Metaplasia in Mucosa Adjacent to Gastric Cancers Is Rarely Associated With the Aneuploidy That Is Characteristic of Gastric Dysplasia or Cancer.

The American journal of surgical pathology

Zhang R, Rabinovitch PS, Mattis AN, Lauwers GY, Choi WT

Persistent or recurrent Barrett's neoplasia after an endoscopic therapy session is associated with DNA content abnormality and can be detected by DNA flow cytometric analysis of paraffin-embedded tissue.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Bowman CJ, Zhang R, Balitzer D, Wang D, Rabinovitch PS, Kovári BP, Mattis AN, Kakar S, Lauwers GY, Choi WT

Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile.

Gastroenterology

Duwaerts CC, Le Guillou D, Her CL, Phillips NJ, Willenbring H, Mattis AN, Maher JJ

Non-conventional dysplasia in inflammatory bowel disease is more frequently associated with advanced neoplasia and aneuploidy than conventional dysplasia.

Histopathology

Lee H, Rabinovitch PS, Mattis AN, Lauwers GY, Choi WT

Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α.

Cell death and differentiation

Duwaerts CC, Siao K, Soon RK, Her C, Iwawaki T, Kohno K, Mattis AN, Maher JJ

Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.

Science translational medicine

Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY

Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.

Scientific reports

Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A

Utility of DNA flow cytometry in distinguishing between malignant and benign intrahepatic biliary lesions.

Virchows Archiv : an international journal of pathology

Wen KW, Rabinovitch PS, Wang D, Mattis AN, Ferrell LD, Choi WT

DNA flow cytometric analysis of paraffin-embedded tissue for the diagnosis of malignancy in bile duct biopsies.

Human pathology

Lee H, Rabinovitch PS, Mattis AN, Kakar S, Choi WT

De novo somatic mutations and KRAS amplification are associated with cholangiocarcinoma in a patient with a history of choledochal cyst.

Journal of pediatric surgery

Schwab ME, Song H, Mattis A, Phelps A, Vu LT, Huang FW, Nijagal A

Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma.

JCI insight

Corbit KC, Wilson CG, Lowe D, Tran JL, Vera NB, Clasquin M, Mattis AN, Weiss EJ

Diagnosis, risk stratification, and management of ampullary dysplasia by DNA flow cytometric analysis of paraffin-embedded tissue.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Wen KW, Kim GE, Rabinovitch PS, Wang D, Mattis AN, Choi WT

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation.

Stem cell research

Kuang YL, Munoz A, Nalula G, Santostefano KE, Sanghez V, Sanchez G, Terada N, Mattis AN, Iacovino M, Iribarren C, Krauss RM, Medina MW

Utility of DNA Flow Cytometric Analysis of Paraffin-embedded Tissue in the Risk Stratification and Management of 'Indefinite for dysplasia' in Patients With Inflammatory Bowel Disease.

Journal of Crohn's & colitis

Wen KW, Rabinovitch PS, Wang D, Huang D, Mattis AN, Choi WT

Depletion of murine fetal hematopoietic stem cells with c-Kit receptor and CD47 blockade improves neonatal engraftment.

Blood advances

Witt RG, Wang B, Nguyen QH, Eikani C, Mattis AN, MacKenzie TC

DNA content analysis of colorectal serrated lesions detects an aneuploid subset of inflammatory bowel disease-associated serrated epithelial change and traditional serrated adenomas.

Histopathology

Choi WT, Wen KW, Rabinovitch PS, Huang D, Mattis AN, Gill RM

Use of DNA flow cytometry in the diagnosis, risk stratification, and management of gastric epithelial dysplasia.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Wen KW, Rabinovitch PS, Huang D, Mattis AN, Lauwers GY, Choi WT

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.

Nature

Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H

CD18 deficiency improves liver injury in the MCD model of steatohepatitis.

PloS one

Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ

Association of Aneuploidy and Flat Dysplasia With Development of High-Grade Dysplasia or Colorectal Cancer in Patients With Inflammatory Bowel Disease.

Gastroenterology

Tsai JH, Rabinovitch PS, Huang D, Small T, Mattis AN, Kakar S, Choi WT

Diagnosis and risk stratification of Barrett's dysplasia by flow cytometric DNA analysis of paraffin-embedded tissue.

Gut

Choi WT, Tsai JH, Rabinovitch PS, Small T, Huang D, Mattis AN, Kakar S

Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver.

Journal of magnetic resonance imaging : JMRI

Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA

A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models.

Journal of medicinal chemistry

Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR

Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5.

Journal of immunology (Baltimore, Md. : 1950)

Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC

Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification.

Development (Cambridge, England)

Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G, Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, Valbuena D, Sim?n C, Laurent LC, Loring JF, Fisher SJ

A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.

Hepatology (Baltimore, Md.)

Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H

Search form

You are here

Aras Mattis, MD, PhD