
Professor
Ob/Gyn, Reproductive Sciences
+1 415 502-4742
Linda Giudice, MD, PhD is the Chair of Obstetrics, Gynecology & Reproductive Sciences. She researches human uterine receptivity in pregnancy and embryo development, and she has initiated studies on human somatic cell nuclear transfer and the differentiation of human embryonic stem cells into placental cells.
Publications
Methylation Risk Score Modelling in Endometriosis: Evidence for Non-Genetic DNA Methylation Effects in a Case-Control Study.
International journal of molecular sciences
Endometriosis and adenomyosis unveiled through single-cell glasses.
American journal of obstetrics and gynecology
Comorbidity analysis and clustering of endometriosis patients using electronic health records.
medRxiv : the preprint server for health sciences
Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.
npj women's health
Two-year efficacy and safety of relugolix combination therapy in women with endometriosis-associated pain: SPIRIT open-label extension study.
Human reproduction (Oxford, England)
Time for global health policy and research leaders to prioritize endometriosis.
Nature communications
A Plain Language Summary to learn about relugolix combination therapy for the treatment of pain associated with endometriosis.
Pain management
Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function.
Communications biology
B-cell lymphoma 6 (BCL6) expression significantly differs by uterine preparation method used for frozen embryo transfer.
Fertility and sterility
Leveraging electronic health records to identify risk factors for recurrent pregnancy loss across two medical centers: a case-control study.
Research square
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions.
Nature genetics
Systematic review of climate change effects on reproductive health.
Fertility and sterility
Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2).
Lancet (London, England)
Response to Boulicault et�al. (2022) from women in the field.
Human fertility (Cambridge, England)
Commentary on the climate crisis and Women's health: Time�for action.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Reproductive biomedicine online
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
Science (New York, N.Y.)
Nutritional interventions to ameliorate the effect of endocrine disruptors on human reproductive health: A semi-structured review from FIGO.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Whole-Tissue Deconvolution and scRNAseq Analysis Identify Altered Endometrial Cellular Compositions and Functionality Associated With Endometriosis.
Frontiers in immunology
Climate change, women's health, and the role of obstetricians and gynecologists in leadership.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Environmental impact on reproductive health and risk mitigating strategies.
Current opinion in obstetrics & gynecology
Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area.
Chemosphere
In Silico, In Vitro, and In Vivo Analysis Identifies Endometrial Circadian Clock Genes in Recurrent Implantation Failure.
The Journal of clinical endocrinology and metabolism
Endometrial function in women with polycystic ovary syndrome: a comprehensive review.
Human reproduction update
Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection.
The New England journal of medicine
Could children born to mothers with COVID-19 be more prone to non-communicable diseases?
Acta paediatrica (Oslo, Norway : 1992)
Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium.
Molecular human reproduction
Patterns of sex hormone receptor expression in stimulated endometrium from oocyte donors.
Human fertility (Cambridge, England)
Eye to the Future in Adenomyosis Research.
Seminars in reproductive medicine
Developing a core outcome set for future infertility research: an international consensus development study� ��.
Human reproduction (Oxford, England)
Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study� ��.
Human reproduction (Oxford, England)
Top 10 priorities for future infertility research: an international consensus development study� ��.
Human reproduction (Oxford, England)
Developing a core outcome set for future infertility research: an international consensus development study.
Fertility and sterility
Standardizing definitions and reporting guidelines for the infertility core outcome set: an international consensus development study.
Fertility and sterility
Top 10 priorities for future infertility research: an international consensus development study.
Fertility and sterility
Cellular Origins of Endometriosis: Towards Novel Diagnostics and Therapeutics.
Seminars in reproductive medicine
Adenomyosis: Mechanisms and Pathogenesis.
Seminars in reproductive medicine
Multidimensional transcriptomic mapping of human endometrium at single-cell resolution.
Nature medicine
Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNFa.
Development (Cambridge, England)
The global impact of COVID-19 on infertility services.
Global reproductive health
m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis.
Frontiers in genetics
A Clarion Warning About Pregnancy Outcomes and the Climate Crisis.
JAMA network open
Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosa of HIV-infected women.
American journal of reproductive immunology (New York, N.Y. : 1989)
Authors' Reply.
Journal of minimally invasive gynecology
Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome.
Scientific reports
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions.
International journal of molecular sciences
Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.
Human reproduction (Oxford, England)
A Pilot Cancer-Phenome Biobanking System in a Low-Resource Southeast Asian Setting: The Philippine General Hospital Biobank Experience.
Biopreservation and biobanking
Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease.
Fertility and sterility
Should Genetics Now Be Considered the Pre-eminent Etiologic Factor in Endometriosis?
Journal of minimally invasive gynecology
25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility.
Fertility and sterility
Before the beginning: environmental exposures and reproductive and obstetrical outcomes.
Fertility and sterility
Reprint of: Pathogenesis and pathophysiology of endometriosis.
Fertility and sterility
The endometrial immune environment of women with endometriosis.
Human reproduction update
Assessing research gaps and unmet needs in endometriosis.
American journal of obstetrics and gynecology
Clinical diagnosis of endometriosis: a call to action.
American journal of obstetrics and gynecology
Establishing the global working group on Reproductive and Developmental Environmental Health (RDEH): practicum of a global resource.
Global reproductive health
Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma.
Biology of reproduction
Forty years of IVF.
Fertility and sterility
Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies.
Obstetrics and gynecology
Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation.
Contemporary clinical trials
In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration.
Journal of assisted reproduction and genetics
Effects of noncavity-distorting fibroids on endometrial gene expression and function.
Biology of reproduction
Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium.
Biology of reproduction
Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers.
Scientific reports
Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist.
The New England journal of medicine
New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity.
The New England journal of medicine
Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility.
Mucosal immunology
World Endometriosis Society consensus on the classification of endometriosis.
Human reproduction (Oxford, England)
Insights from imaging the implanting embryo and the uterine environment in three dimensions.
Development (Cambridge, England)
Challenging dogma: the endometrium has a microbiome with functional consequences!
American journal of obstetrics and gynecology
Research Priorities for Endometriosis.
Reproductive sciences (Thousand Oaks, Calif.)
Environmental toxicants: hidden players on the reproductive stage.
Fertility and sterility
Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis.
Biology of reproduction
Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and�endometrium.
American journal of reproductive immunology (New York, N.Y. : 1989)
Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis.
Fertility and sterility
Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis.
Reproductive sciences (Thousand Oaks, Calif.)
Moving from awareness to action on preventing patient exposure to toxic environmental chemicals.
American journal of obstetrics and gynecology
Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis.
Biology of reproduction
Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity.
Fertility and sterility
International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome.
Human reproduction update
Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012".
Regulatory toxicology and pharmacology : RTP
Update on Biomarkers for the Detection of Endometriosis.
BioMed research international
Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal.
Human reproduction (Oxford, England)
Kr�ppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis.
Biology of reproduction
Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro.
Human reproduction (Oxford, England)
Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix.
Reproductive sciences (Thousand Oaks, Calif.)
Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals.
Journal of proteomics
Molecular classification of endometriosis and disease stage using high-dimensional genomic data.
Endocrinology
World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research.
Fertility and sterility
World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research.
Fertility and sterility
World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research.
Fertility and sterility
Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation.
Molecular endocrinology (Baltimore, Md.)
Impact of surgical excision of lesions on pain in a rat model of endometriosis.
European journal of pain (London, England)
Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts.
Human reproduction (Oxford, England)
Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women.
American journal of reproductive immunology (New York, N.Y. : 1989)
Ectopic endometrium-derived leptin produces estrogen-dependent chronic pain in a rat model of endometriosis.
Neuroscience
Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium.
Human reproduction update
Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors.
Environmental health : a global access science source
Elagolix, an Oral GnRH Antagonist for Endometriosis-Associated Pain: A Randomized Controlled Study.
Journal of endometriosis and pelvic pain disorders
The human oviduct transcriptome reveals an anti-inflammatory, anti-angiogenic, secretory and matrix-stable environment during embryo transit.
Reproductive biomedicine online
Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production.
Fertility and sterility
Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential.
The Journal of clinical endocrinology and metabolism
Diversity of the vaginal microbiome correlates with preterm birth.
Reproductive sciences (Thousand Oaks, Calif.)
Retrospective. Robert G. Edwards (1925-2013).
Science (New York, N.Y.)
Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study.
Fertility and sterility
Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis.
Biology of reproduction
Defining future directions for endometriosis research: workshop report from the 2011 World Congress of Endometriosis In Montpellier, France.
Reproductive sciences (Thousand Oaks, Calif.)
Perfluorochemicals and endometriosis: the ENDO study.
Epidemiology (Cambridge, Mass.)
Role of decreased androgens in the ovarian response to stimulation in older women.
Fertility and sterility
Ectopic uterine tissue as a chronic pain generator.
Neuroscience
Pathogenesis and pathophysiology of endometriosis.
Fertility and sterility
Persistent lipophilic environmental chemicals and endometriosis: the ENDO Study.
Environmental health perspectives
Molecular probe technology detects bacteria without culture.
BMC microbiology
Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures.
American journal of obstetrics and gynecology
Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype.
Biology of reproduction
Kr�ppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis.
The Journal of clinical endocrinology and metabolism
Comparative transcriptome analysis of human trophectoderm and embryonic stem cell-derived trophoblasts reveal key participants in early implantation.
Biology of reproduction
The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer.
Journal of assisted reproduction and genetics
High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples.
Human reproduction (Oxford, England)
Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis.
Reproductive sciences (Thousand Oaks, Calif.)
A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder.
American heart journal
SGK1: a fine balancing act for human pregnancy.
Nature medicine
Incidence of endometriosis by study population and diagnostic method: the ENDO study.
Fertility and sterility
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
The Journal of clinical endocrinology and metabolism
Biobanking human endometrial tissue and blood specimens: standard operating procedure and importance to reproductive biology research and diagnostic development.
Fertility and sterility
Transcriptomic signature of trophoblast differentiation in a human embryonic stem cell model.
Biology of reproduction
Effect of bisphenol A on human endometrial stromal fibroblasts in vitro.
Reproductive biomedicine online
Reproductive environmental health.
Current opinion in obstetrics & gynecology
Molecular evidence for differences in endometrium in severe versus mild endometriosis.
Reproductive sciences (Thousand Oaks, Calif.)
Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.
Biology of reproduction
Clinical practice. Endometriosis.
The New England journal of medicine
Racial and ethnic disparities in benign gynecologic conditions and associated surgeries.
American journal of obstetrics and gynecology
Research agenda for environmental reproductive health in the 21st century.
Journal of epidemiology and community health
Racial and ethnic disparities in reproductive endocrinology and infertility.
American journal of obstetrics and gynecology
Research ethics. NIH guidelines for stem cell research and gamete donors.
Science (New York, N.Y.)
The bone marrow-derived human mesenchymal stem cell: potential progenitor of the endometrial stromal fibroblast.
Biology of reproduction
Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility.
Biology of reproduction
Altered gene expression profiling in endometrium: evidence for progesterone resistance.
Seminars in reproductive medicine
Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.
Cell stem cell
Gene expression during successful implantation in a natural cycle.
Fertility and sterility
Peroxisome proliferator-activated receptor-gamma mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells.
Environmental health perspectives
MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis.
Molecular human reproduction
Body mass index and intercourse compliance.
Fertility and sterility
Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial.
Fertility and sterility
Predictors of pregnancy in women with polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism
Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.
Proceedings of the National Academy of Sciences of the United States of America
Editorial: Update on stem cell research.
Endocrine reviews
The progesterone receptor coactivator Hic-5 is involved in the pathophysiology of endometriosis.
Endocrinology
Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns.
Cell stem cell
Priorities for endometriosis research: recommendations from an international consensus workshop.
Reproductive sciences (Thousand Oaks, Calif.)
The interplay of insulin-like growth factors, gonadotropins, and endocrine disruptors in ovarian follicular development and function.
Seminars in reproductive medicine
Genomics analysis: endometrium.
Methods in molecular biology (Clifton, N.J.)
From stem cells to germ cells and back again.
Nature medicine
Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.
Fertility and sterility
Steroidogenic enzyme and key decidualization marker dysregulation in endometrial stromal cells from women with versus without endometriosis.
Biology of reproduction
Environmental exposures and adverse pregnancy outcomes: a review of the science.
Reproductive sciences (Thousand Oaks, Calif.)
Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications.
The Journal of clinical endocrinology and metabolism
VEGF blockade inhibits angiogenesis and reepithelialization of endometrium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Endometrial gene expression in early pregnancy: lessons from human ectopic pregnancy.
Reproductive sciences (Thousand Oaks, Calif.)
Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism
Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer.
Reproductive biomedicine online
The impact of ovarian stimulation with recombinant FSH in combination with GnRH antagonist on the endometrial transcriptome in the window of implantation.
Reproductive sciences (Thousand Oaks, Calif.)
Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary.
Fertility and sterility
Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary.
Fertility and sterility
Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone.
The Journal of endocrinology
Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial.
Fertility and sterility
Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene.
The Journal of clinical endocrinology and metabolism
The influence of hydrosalpinx on markers of endometrial receptivity.
Seminars in reproductive medicine
Uterine receptivity to human embryonic implantation: histology, biomarkers, and transcriptomics.
Seminars in cell & developmental biology
Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.
The New England journal of medicine
Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome.
Fertility and sterility
Decidual stromal cell response to paracrine signals from the trophoblast: amplification of immune and angiogenic modulators.
Biology of reproduction
Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.
The Journal of clinical investigation
Infertility and the environment: the medical context.
Seminars in reproductive medicine
A twenty-first century research agenda for polycystic ovary syndrome.
Best practice & research. Clinical endocrinology & metabolism
Endometrium in PCOS: Implantation and predisposition to endocrine CA.
Best practice & research. Clinical endocrinology & metabolism
Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells.
The Journal of clinical endocrinology and metabolism
Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth.
Molecular human reproduction
Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation.
Reproduction, fertility, and development
Application of functional genomics to primate endometrium: insights into biological processes.
Reproductive biology and endocrinology : RB&E
Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation.
Lymphatic research and biology
Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles.
Fertility and sterility
The dilemma of endometriosis: is consensus possible with an enigma?
Fertility and sterility
IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch.
Molecular human reproduction
Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome.
Human reproduction (Oxford, England)
Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.
Endocrinology
Microbes on the human vaginal epithelium.
Proceedings of the National Academy of Sciences of the United States of America
Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives.
Endocrine reviews
Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements.
The Journal of biological chemistry
Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic Acid in the human and rhesus macaque endometrium.
The Journal of clinical endocrinology and metabolism
Dose-dependent insulin regulation of insulin-like growth factor binding protein-1 in human endometrial stromal cells is mediated by distinct signaling pathways.
The Journal of clinical endocrinology and metabolism
Absence of secretory endometrium after false-positive home urine luteinizing hormone testing.
Fertility and sterility
Endometriosis.
Lancet (London, England)
The immune environment in human endometrium during the window of implantation.
American journal of reproductive immunology (New York, N.Y. : 1989)
Silencing lamin A/C in human endometrial stromal cells: a model to investigate endometrial gene function and regulation.
Molecular human reproduction
Developmental response to hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.
The Journal of biological chemistry
Interferon-related and other immune genes are downregulated in peripheral blood leukocytes in the luteal phase of the menstrual cycle.
The Journal of clinical endocrinology and metabolism
Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module.
European journal of biochemistry
Role of activin A as a mediator of in vitro endometrial stromal cell decidualization via the cyclic adenosine monophosphate pathway.
Fertility and sterility
Microarray expression profiling reveals candidate genes for human uterine receptivity.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice
Activation of the protein kinase A pathway in human endometrial stromal cells reveals sequential categorical gene regulation.
Physiological genomics
Comparison of the sex ratio with blastocyst transfer and cleavage stage transfer.
Journal of assisted reproduction and genetics
Identification, characterization, and regulation of the canonical Wnt signaling pathway in human endometrium.
The Journal of clinical endocrinology and metabolism
Prenatal screening, epidemiology, diagnosis, and management of preeclampsia.
Clinics in laboratory medicine
Elucidating endometrial function in the post-genomic era.
Human reproduction update
Genomics' role in understanding the pathogenesis of endometriosis.
Seminars in reproductive medicine
Incidence of monozygotic twinning with blastocyst transfer compared to cleavage-stage transfer.
Fertility and sterility
Regulation of insulin-like growth factor-I and insulin-like growth factor binding protein-1 concentrations in preterm fetuses.
American journal of obstetrics and gynecology
Predictors of ovulatory failure in women with epilepsy.
Annals of neurology
Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane.
The Journal of clinical endocrinology and metabolism
Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.
The Journal of biological chemistry
Emerging role of genomics in endometriosis research.
Fertility and sterility
Maternal-fetal conflict--lessons from a transgene.
The Journal of clinical investigation
Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation.
The Journal of clinical endocrinology and metabolism
A longitudinal analysis of maternal serum insulin-like growth factor I (IGF-I) and total and nonphosphorylated IGF-binding protein-1 in human pregnancies complicated by intrauterine growth restriction.
The Journal of clinical endocrinology and metabolism
Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity.
European journal of biochemistry
The molecular basis for implantation failure in endometriosis: on the road to discovery.
Annals of the New York Academy of Sciences
Prediction of the individual follicle-stimulating hormone threshold for gonadotropin induction of ovulation in normogonadotropic anovulatory infertility: an approach to increase safety and efficiency.
Fertility and sterility
Insulin-like growth factor-binding protein-1 in umbilical artery and vein of term fetuses with signs suggestive of distress during labor.
The Journal of endocrinology
A potential role for insulin-like growth factor binding protein-4 proteolysis in the establishment of ovarian follicular dominance in cattle.
Biology of reproduction
Hypoxia regulates insulin-like growth factor-binding protein 1 in human fetal hepatocytes in primary culture: suggestive molecular mechanisms for in utero fetal growth restriction caused by uteroplacental insufficiency.
The Journal of clinical endocrinology and metabolism
Insulin-like growth factor (IGF)-II inhibition of endometrial stromal cell tissue inhibitor of metalloproteinase-3 and IGF-binding protein-1 suggests paracrine interactions at the decidua:trophoblast interface during human implantation.
The Journal of clinical endocrinology and metabolism
Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development.
International journal of cancer
Insulin-like growth factor family in Graafian follicle development and function.
Journal of the Society for Gynecologic Investigation
Multiple pregnancies: what action should we take?
Fertility and sterility
Ovarian follicular concentrations of activin, follistatin, inhibin, insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-2 (IGFBP-2), IGFBP-3, and vascular endothelial growth factor in spontaneous menstrual cycles of normal women of advanced
The Journal of clinical endocrinology and metabolism
Regulation of insulin-like growth factor-binding protein 1 by hypoxia and 3',5'-cyclic adenosine monophosphate is additive in HepG2 cells.
The Journal of clinical endocrinology and metabolism
Discovery of new inducible genes in in vitro decidualized human endometrial stromal cells using microarray technology.
Endocrinology
Regulation of insulin-like growth factor-binding protein-1 by nitric oxide under hypoxic conditions.
The Journal of clinical endocrinology and metabolism
Free androgen index and leptin are the most prominent endocrine predictors of ovarian response during clomiphene citrate induction of ovulation in normogonadotropic oligoamenorrheic infertility.
The Journal of clinical endocrinology and metabolism
Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium.
International journal of cancer
Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A.
The Journal of clinical endocrinology and metabolism
Potential biochemical markers of uterine receptivity.
Human reproduction (Oxford, England)
Role of the IGF system in trophoblast invasion and pre-eclampsia.
Human reproduction (Oxford, England)
Elevated serum levels of free insulin-like growth factor I in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism
The insulin-related ovarian regulatory system in health and disease.
Endocrine reviews
Growth factor action on ovarian function in polycystic ovary syndrome.
Endocrinology and metabolism clinics of North America
Hypoxia and cAMP stimulate vascular endothelial growth factor (VEGF) in human endometrial stromal cells: potential relevance to menstruation and endometrial regeneration.
The Journal of clinical endocrinology and metabolism
Insulin-like growth factor-II mediates the steroidogenic and growth promoting actions of follicle stimulating hormone on human ovarian pre-antral follicles cultured in vitro.
The Journal of clinical endocrinology and metabolism
Genes associated with embryonic attachment and implantation and the role of progesterone.
The Journal of reproductive medicine
Roles of the insulinlike growth factor family in nonpregnant human endometrium and at the decidual: trophoblast interface.
Seminars in reproductive endocrinology
Dysfunctional uterine bleeding.
The Western journal of medicine
Growth factor regulation of insulin-like growth factor binding protein secretion by cultured human granulosa-luteal cells.
Fertility and sterility
Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia.
Proceedings of the National Academy of Sciences of the United States of America
Paracrine actions of insulin-like growth factors and IGF binding protein-1 in non-pregnant human endometrium and at the decidual-trophoblast interface.
Journal of reproductive immunology
Medical management of interstitial ectopic pregnancy: a case report and literature review.
Human reproduction (Oxford, England)
Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.
The Journal of clinical endocrinology and metabolism
Status of current research on endometriosis.
The Journal of reproductive medicine
Insulin-like growth factor binding protein-1 binds to placental cytotrophoblast alpha5beta1 integrin and inhibits cytotrophoblast invasion into decidualized endometrial stromal cultures.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Insulin-like growth factor binding protein-1: recent findings and new directions.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Multifaceted roles for IGFBP-1 in human endometrium during implantation and pregnancy.
Annals of the New York Academy of Sciences
Developmental regulation of telomerase activity in human fetal tissues during gestation.
Molecular human reproduction
Programmed cell death in human ovary is a function of follicle and corpus luteum status.
The Journal of clinical endocrinology and metabolism
Insulin-like growth factors and insulin-like growth factor binding proteins in androgen-dominant ovarian follicles from testosterone-treated female-to-male trans-sexuals.
Fertility and sterility
Gestational age-dependent expression of insulin-like growth factor-binding protein-1 (IGFBP-1) phosphoisoforms in human extraembryonic cavities, maternal serum, and decidua suggests decidua as the primary source of IGFBP-1 in these fluids during early pre
The Journal of clinical endocrinology and metabolism
Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia.
American journal of obstetrics and gynecology
Laparoscopic management of a noncommunicating uterine horn in a patient with an acute abdomen.
Surgical laparoscopy & endoscopy
Role of growth hormone in ovarian physiology and onset of puberty.
Journal of the Society for Gynecologic Investigation
Growth factors and cytokines in endometrium, embryonic development, and maternal: embryonic interactions.
Seminars in reproductive endocrinology
Growth factors and polycystic ovarian syndrome.
Seminars in reproductive endocrinology
Growth factors in normal ovarian follicle development.
Seminars in reproductive endocrinology
Insulin-like growth factor binding proteins in peritoneal fluid of women with minimal and mild endometriosis.
Human reproduction (Oxford, England)
Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age.
The Journal of clinical endocrinology and metabolism
Polycystic ovary syndrome.
Human reproduction (Oxford, England)
Serum and follicular fluid levels of insulin-like growth factor I (IGF-I), IGF-II, and IGF-binding protein-1 and -3 during the normal menstrual cycle.
The Journal of clinical endocrinology and metabolism
Insulin receptor mediates inhibitory effect of insulin, but not of insulin-like growth factor (IGF)-I, on IGF binding protein 1 (IGFBP-1) production in human granulosa cells.
The Journal of clinical endocrinology and metabolism
Human endometrial matrix metalloproteinase-2, a putative menstrual proteinase. Hormonal regulation in cultured stromal cells and messenger RNA expression during the menstrual cycle.
The Journal of clinical investigation
Different molecular and messenger ribonucleic acid forms of insulin-like growth factor-binding protein-3 in the pregnant baboon (Papio anubis).
The Journal of endocrinology
Estrogen- but not androgen-dominant human ovarian follicular fluid contains an insulin-like growth factor binding protein-4 protease.
The Journal of clinical endocrinology and metabolism
IGF binding protein-3 protease regulation: how sweet it is!
The Journal of clinical endocrinology and metabolism
Radiation-induced premature menopause: a misconception.
International journal of radiation oncology, biology, physics
Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth.
The Journal of clinical endocrinology and metabolism
Follicular fluid insulin-like growth factor-I and insulin-like growth factor-II concentrations vary as a function of day 3 serum follicle stimulating hormone.
Human reproduction (Oxford, England)
Ovulatory function in epilepsy.
Epilepsia
Growth factors in reproduction.
Trends in endocrinology and metabolism: TEM
Regulation of insulin-like growth factor-binding protein-4 in human endometrial stromal cell cultures: evidence for ligand-induced proteolysis.
The Journal of clinical endocrinology and metabolism
The insulin-like growth factor system in normal and abnormal human ovarian follicle development.
The American journal of medicine
Circulating and ovarian IGF binding proteins: potential roles in normo-ovulatory cycles and in polycystic ovarian syndrome.
Progress in growth factor research
Insulin-like growth factor system gene expression in human endometrium during the menstrual cycle.
The Journal of clinical endocrinology and metabolism
Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) fragments and IGFBP-5 proteolytic activity in human seminal plasma: a comparison of normal and vasectomized patients.
The Journal of clinical endocrinology and metabolism
Insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and proteolyzed IGFBP-3 in embryonic cavities in early human pregnancy: their potential relevance to maternal-embryonic and fetal interactions.
The Journal of clinical endocrinology and metabolism
The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis.
The Journal of clinical endocrinology and metabolism
Growth factors and decidualization in vitro.
Annals of the New York Academy of Sciences
Insulin-like growth factor-binding proteins in the human fetus: tissue-specific protein secretion, immunologic characterization, and gene expression.
American journal of obstetrics and gynecology
Patterns of matrix metalloproteinase expression in cycling endometrium imply differential functions and regulation by steroid hormones.
The Journal of clinical investigation
Adnexal torsion: color Doppler diagnosis and laparoscopic treatment.
Fertility and sterility
Growth factors and growth modulators in human uterine endometrium: their potential relevance to reproductive medicine.
Fertility and sterility
Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata.
Human reproduction (Oxford, England)
Ethics of fetal tissue transplantation.
The Western journal of medicine
The potential roles of intraovarian peptides in normal and abnormal mechanisms of reproductive physiology.
Current opinion in obstetrics & gynecology
Differential expression of messenger ribonucleic acids encoding insulin-like growth factors and their receptors in human uterine endometrium and decidua.
The Journal of clinical endocrinology and metabolism
Proteolysis of IGFBP-3 may be a common regulatory mechanism of IGF action in vivo.
Growth regulation
Comparison of functional response of rat, macaque, and human ovarian cells in hormonally defined medium.
Biology of reproduction
Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle.
American journal of obstetrics and gynecology
Regulation of insulin-like growth factor binding protein production by human luteinizing granulosa cells cultured in defined medium.
The Journal of clinical endocrinology and metabolism
Local anesthesia with conscious sedation for laparoscopic intrafallopian transfer.
Fertility and sterility
Insulin-like growth factors and ovarian follicular development.
Endocrine reviews
Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation.
The Journal of clinical endocrinology and metabolism
Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma.
The Journal of clinical endocrinology and metabolism
Insulin-like growth factor binding protein profiles in human ovarian follicular fluid correlate with follicular functional status.
The Journal of clinical endocrinology and metabolism
Follicular fluid insulin-like growth factor binding protein profiles in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism
Identification of insulin-like growth factor binding proteins in human oviduct.
Fertility and sterility
Maternal insulin-like growth factor-binding protein messenger ribonucleic acid during rat pregnancy.
Endocrinology
Human granulosa contain messenger ribonucleic acids encoding insulin-like growth factor-binding proteins (IGFBPs) and secrete IGFBPs in culture.
Fertility and sterility
A simple assay for proteolysis of IGFBP-3.
The Journal of clinical endocrinology and metabolism
Characterization of the steroid-dependence of insulin-like growth factor-binding protein-2 synthesis and mRNA expression in cultured human endometrial stromal cells.
Human reproduction (Oxford, England)
Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis.
The Journal of clinical endocrinology and metabolism
Clinical aspects of insulin-like growth factor binding proteins.
Acta endocrinologica
Insulin-like growth factor binding proteins: structural and molecular relationships.
Growth factors (Chur, Switzerland)
Insulin-like growth factor-II (IGF-II) and IGF binding proteins in human endometrium.
Annals of the New York Academy of Sciences
Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) and IGFBP-2 in human follicular fluid.
The Journal of clinical endocrinology and metabolism
Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity.
The Journal of clinical endocrinology and metabolism
Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma.
The Journal of clinical endocrinology and metabolism
Insulinlike growth factor-binding proteins.
Recent progress in hormone research
Expression of two insulin-like growth factor-binding proteins in a human endometrial cancer cell line: structural, immunological, and genetic characterization.
The Journal of clinical endocrinology and metabolism
Cryopreservation of embryos and ova.
Fertility and sterility
Angiographic arterial embolization to control hemorrhage in abdominal pregnancy: a case report.
Obstetrics and gynecology
Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman.
Fertility and sterility
Clinical results of Stanford University's in vitro fertilization and embryo transfer program.
Journal of in vitro fertilization and embryo transfer : IVF
Serum levels of CA-125 in patients with endometriosis: a preliminary report.
Fertility and sterility
The function of the common subunit of glycoprotein hormones.
Biochemical Society Transactions
Separation of functional and non-functional beta subunits of thyrotropin preparations by polyacrylamide gel electrophoresis.
Endocrinology
Studies on the disulfide bonds of glycoprotein hormones. Complete reduction and reoxidation of the disulfide bonds of the alpha subunit of bovine luteinizing hormone.
The Journal of biological chemistry
Studies on the disulfide bonds of glycoprotein hormones. Course of reduction of bovine luteinizing hormone, bovine thyroid-stimulating hormone, and their subunits.
The Journal of biological chemistry
Structure and structure-function relationships in glycoprotein hormones.
Ciba Foundation symposium