
Professor
Pediatrics
+1 415 476-3748
Stephen Gitelman, MD is the Director of the UCSF Pediatric Diabetes Program and has active clinical research interests in diabetes, particularly in the prevention of type 1 diabetes mellitus.
Publications
Exploring Microbiota-Associated Metabolites in Twins Discordant for Type 1 Diabetes.
medRxiv : the preprint server for health sciences
Real-world experiences of adult individuals or caregivers of children who received teplizumab treatment in stage 2 type 1 diabetes.
Diabetes, obesity & metabolism
Felix A. Conte, MD 1935-2024. The endocrinologist's endocrinologist.
Hormone research in paediatrics
Felix A. Conte, MD 1935-2024. The endocrinologist's endocrinologist.
Hormone research in paediatrics
Time to reframe the disease staging system for type 1 diabetes.
The lancet. Diabetes & endocrinology
Early Metabolic Endpoints Identify Persistent Treatment Efficacy in Recent-Onset Type 1 Diabetes Immunotherapy Trials.
Diabetes care
A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes.
Science translational medicine
The Role of Imatinib in Pediatric Type 1 Diabetes.
JCEM case reports
Pediatric Endocrine Society Statement on Considerations for Use of Teplizumab (Tzield™) in Clinical Practice.
Hormone research in paediatrics
Hydroxychloroquine in Stage 1 Type 1 Diabetes.
Diabetes care
Teplizumab and β-Cell Function in Newly Diagnosed Type 1 Diabetes.
The New England journal of medicine
Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review.
Communications medicine
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
Nature medicine
Teplizumab: A Disease-Modifying Therapy for Type 1 Diabetes That Preserves β-Cell Function.
Diabetes care
Type 1 Diabetes Prevention: a systematic review of studies testing disease-modifying therapies and features linked to treatment response.
medRxiv : the preprint server for health sciences
Real-Time Continuous Glucose Monitoring in Adolescents and Young Adults With Type 2 Diabetes Can Improve Quality of Life.
Journal of diabetes science and technology
The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes.
JCI insight
Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample.
Diabetologia
Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.
The lancet. Diabetes & endocrinology
Youth with Type 1 Diabetes Had Improvement in Continuous Glucose Monitoring Metrics During the COVID-19 Pandemic.
Diabetes technology & therapeutics
Continuous Glucose Monitoring to Diagnose Hypoglycemia Due to Late Dumping Syndrome in Children After Gastric Surgeries.
Journal of the Endocrine Society
Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes.
Diabetes technology & therapeutics
Exenatide extended release in patients with type 1 diabetes with and without residual insulin production.
Diabetes, obesity & metabolism
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.
Diabetes care
Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome.
Xenotransplantation
An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.
The New England journal of medicine
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables.
Diabetologia
Low-Dose Anti-Thymocyte Globulin (ATG) Preserves �-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes.
Diabetes care
The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults.
The Journal of clinical endocrinology and metabolism
A new familial form of a late-onset, persistent hyperinsulinemic hypoglycemia of infancy caused by a novel mutation in KCNJ11.
Channels (Austin, Tex.)
Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs.
Transplantation
Regulatory T cell therapy for type 1 diabetes: May the force be with you.
Journal of autoimmunity
Two- and Four-Hour Tests Differ in Capture of C-Peptide Responses to a Mixed Meal in Type 1 Diabetes.
Diabetes care
Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2�year results of a randomised trial.
Diabetologia
Type 1 diabetes immunotherapy using polyclonal regulatory T cells.
Science translational medicine
Defining pathways for development of disease-modifying therapies in children with type 1 diabetes: a consensus report.
Diabetes care
Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients.
The Journal of clinical investigation
Anti-thymocyte globulin/G-CSF treatment preserves � cell function in patients with established type 1 diabetes.
The Journal of clinical investigation
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial.
The lancet. Diabetes & endocrinology
Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial.
The lancet. Diabetes & endocrinology
Altering the course of type 1 diabetes: an update on prevention and new-onset clinical trials.
Pediatric diabetes
Combined pancreatic islet and kidney transplantation in a child with unstable type 1 diabetes and end-stage renal disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Comparison of autoantibody-positive and autoantibody-negative pediatric participants enrolled in the T1D Exchange clinic registry.
Journal of diabetes
Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials.
Lancet (London, England)
A cross-sectional study of osteocalcin and body fat measures among obese adolescents.
Obesity (Silver Spring, Md.)
Persistent elevation of urine aquaporin-2 during water loading in a child with nephrogenic syndrome of inappropriate antidiuresis (NSIAD) caused by a R137L mutation in the V2 vasopressin receptor.
International journal of pediatric endocrinology
Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
Lancet (London, England)
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial.
Lancet (London, England)
Detecting and treating hyperlipidemia in children with type 1 diabetes mellitus: are standard guidelines applicable to this special population?
Pediatric diabetes
Impact of an interactive online nursing educational module on insulin errors in hospitalized pediatric patients.
Diabetes care
Long-term outcomes in a family with nephrogenic syndrome of inappropriate antidiuresis.
International journal of pediatric endocrinology
Rituximab, B-lymphocyte depletion, and preservation of beta-cell function.
The New England journal of medicine
Relation of body fat indexes to vitamin D status and deficiency among obese adolescents.
The American journal of clinical nutrition
Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years.
Clinical immunology (Orlando, Fla.)
The effect of oral alpha-lipoic acid on oxidative stress in adolescents with type 1 diabetes mellitus.
Pediatric diabetes
Congenital hyperinsulinism in an infant caused by a macroscopic insulin-producing lesion.
Journal of pediatric endocrinology & metabolism : JPEM
Nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a paradigm for activating mutations causing endocrine dysfunction.
Pediatric endocrinology reviews : PER
Nephrogenic syndrome of inappropriate antidiuresis: a novel disorder in water balance in pediatric patients.
The American journal of medicine
Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children.
The Journal of pediatrics
Prevalence and characteristics of type 2 diabetes mellitus in 9-18 year-old children with diabetic ketoacidosis.
Journal of pediatric endocrinology & metabolism : JPEM
Nephrogenic syndrome of inappropriate antidiuresis.
The New England journal of medicine
A two-center randomized controlled feasibility trial of insulin pump therapy in young children with diabetes.
Diabetes care
The use of a continuous glucose monitoring system in hypoglycemic disorders.
Journal of pediatric endocrinology & metabolism : JPEM
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus.
The New England journal of medicine
Transition from multiple daily injections to continuous subcutaneous insulin infusion in type 1 diabetes mellitus.
The Journal of pediatrics
Increased incidence in post-transplant diabetes mellitus in children: a case-control analysis.
Pediatric nephrology (Berlin, Germany)
Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass.
Development (Cambridge, England)
Smooth muscle expresses bone morphogenetic protein (Vgr-1/BMP-6) in human fetal intestine.
Biology of the neonate
Neonatal hyperinsulinism.
Clinics in perinatology
Long-term outcome in children and adolescents after transsphenoidal surgery for Cushing's disease.
The Journal of clinical endocrinology and metabolism
Idiopathic hypothalamic diabetes insipidus, pituitary stalk thickening, and the occult intracranial germinoma in children and adolescents.
The Journal of clinical endocrinology and metabolism
Structure and sequence of the mouse Bmp6 gene.
Mammalian genome : official journal of the International Mammalian Genome Society
Immunoreactive inhibin, müllerian inhibitory substance, and activin as biochemical markers for juvenile granulosa cell tumors.
The Journal of pediatrics
A promoter within intron 35 of the human C4A gene initiates abundant adrenal-specific transcription of a 1 kb RNA: location of a cryptic CYP21 promoter element?
Human molecular genetics
Vgr-1/BMP-6 induces osteoblastic differentiation of pluripotential mesenchymal cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo.
The Journal of cell biology
Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.
The Journal of cell biology
Abundant adrenal-specific transcription of the human P450c21A "pseudogene".
The Journal of biological chemistry
Mental retardation locus in Xp21 chromosome microdeletion.
American journal of medical genetics
Congenital lipoid adrenal hyperplasia--genes for P450scc, side chain cleavage enzyme, are normal.
The Journal of steroid biochemistry and molecular biology
Analysis of the duplicated human C4/P450c21/X gene cluster.
The Journal of steroid biochemistry and molecular biology
Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus.
Molecular and cellular biology
Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus.
Molecular and cellular biology
Normal genes for the cholesterol side chain cleavage enzyme, P450scc, in congenital lipoid adrenal hyperplasia.
The Journal of clinical investigation
Cloning of the LH/CG receptor: implications for a unique G-protein coupled receptor.
Trends in endocrinology and metabolism: TEM
Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus.
Proceedings of the National Academy of Sciences of the United States of America
Purification of calmodulin from Chlamydomonas: calmodulin occurs in cell bodies and flagella.
The Journal of cell biology