Tobias Deuse, MD

Professor
Surgery

Tobias Deuse, MD is developing immune editing strategies to shield stem cells and cell products from immune recognition and rejection. He develops immune-oncology therapeutics and regenerative cell therapies based on this concept.

Publications: 

Clinical Improvement With Transcatheter Edge-to-Edge Tricuspid Repair Irrespective of Right Atrial Pressure.

JACC. Advances

Ya'Qoub L, Caughron H, Qasim A, Tolstrop K, Delling FN, Watt C, Nguyen T, Deuse T, Beygui RE, Mahadevan VS

Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate.

Cell stem cell

Hu X, White K, Young C, Olroyd AG, Kievit P, Connolly AJ, Deuse T, Schrepfer S

Four Decades of Progress in Heart-Lung Transplantation: 271 Cases at a Single Institution.

The Journal of thoracic and cardiovascular surgery

Elde S, Baccouche BM, Mullis DM, Leipzig MM, Deuse T, Krishnan A, Fawad M, Dale R, Walsh S, Padilla-Lopez A, Wesley B, He H, Yajima S, Zhu Y, Wang H, Guenthart BA, Shudo Y, Reitz BA, Woo YJ

Lung Transplantation in Patients with Cystic Fibrosis: A Complex Task, A Changing Target.

Journal of cardiothoracic and vascular anesthesia

Loebe M, Deuse T, Sinha N, Koster A, Erdoes G

Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity.

Cell stem cell

Gravina A, Tediashvili G, Zheng Y, Iwabuchi KA, Peyrot SM, Roodsari SZ, Gargiulo L, Kaneko S, Osawa M, Schrepfer S, Deuse T

Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques.

Nature biotechnology

Hu X, White K, Olroyd AG, DeJesus R, Dominguez AA, Dowdle WE, Friera AM, Young C, Wells F, Chu EY, Ito CE, Krishnapura H, Jain S, Ankala R, McGill TJ, Lin A, Egenberger K, Gagnon A, Michael Rukstalis J, Hogrebe NJ, Gattis C, Basco R, Millman JR, Kievit P, Davis MM, Lanier LL, Connolly AJ, Deuse T, Schrepfer S

Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice.

Science translational medicine

Hu X, Gattis C, Olroyd AG, Friera AM, White K, Young C, Basco R, Lamba M, Wells F, Ankala R, Dowdle WE, Lin A, Egenberger K, Rukstalis JM, Millman JR, Connolly AJ, Deuse T, Schrepfer S

Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice.

Nature communications

Hu X, Manner K, DeJesus R, White K, Gattis C, Ngo P, Bandoro C, Tham E, Chu EY, Young C, Wells F, Basco R, Friera A, Kangeyan D, Beauchesne P, Dowdle WE, Deuse T, Fry TJ, Foster AE, Schrepfer S

Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression.

Nature biotechnology

Gravina A, Tediashvili G, Rajalingam R, Quandt Z, Deisenroth C, Schrepfer S, Deuse T

Morbidity and Mortality Associated With Blood Transfusions in Elective Adult Cardiac Surgery.

Journal of cardiothoracic and vascular anesthesia

Sanaiha Y, Hadaya J, Verma A, Shemin RJ, Madani M, Young N, Deuse T, Sun J, Benharash P, University of California Cardiac Surgery Consortium

Author Correction: Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.

Nature biotechnology

Deuse T, Hu X, Gravina A, Wang D, Tediashvili G, De C, Thayer WO, Wahl A, Garcia JV, Reichenspurner H, Davis MM, Lanier LL, Schrepfer S

Intercostal Nerve Cryoanalgesia Versus Thoracic Epidural Analgesia in Lung Transplantation: A Retrospective Single-Center Study.

Pain and therapy

Isaza E, Santos J, Haro GJ, Chen J, Weber DJ, Deuse T, Singer JP, Golden JA, Hays S, Trinh BN, Brzezinski M, Kukreja J

Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.

Proceedings of the National Academy of Sciences of the United States of America

Deuse T, Tediashvili G, Hu X, Gravina A, Tamenang A, Wang D, Connolly A, Mueller C, Mallavia B, Looney MR, Alawi M, Lanier LL, Schrepfer S

Shock, Thrombus, TAVR: A Challenging TAVR With Large Left-Ventricular Thrombus.

The Canadian journal of cardiology

Blusztein D, Teng P, Deuse T, Mahadevan VS

Immunomodulation Therapy Using Tolerogenic Macrophages in a Rodent Model of Pulmonary Hypertension.

Stem cells and development

Guihaire J, Deuse T, Wang D, Spin JM, Blankenberg FG, Fadel E, Reichenspurner H, Schrepfer S

The SIRPa-CD47 immune checkpoint in NK cells.

The Journal of experimental medicine

Deuse T, Hu X, Agbor-Enoh S, Jang MK, Alawi M, Saygi C, Gravina A, Tediashvili G, Nguyen VQ, Liu Y, Valantine H, Lanier LL, Schrepfer S

Outcomes of transcatheter aortic valve replacement in end stage liver and renal disease.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Caughron H, Parikh D, Allison Z, Deuse T, Mahadevan VS

Subxiphoid Hybrid Epicardial-Endocardial Atrial Fibrillation Ablation and LAA�Ligation: Initial Sub-X Hybrid MAZE Registry Results.

JACC. Clinical electrophysiology

Ellis CR, Badhwar N, Tschopp D, Danter M, Jackson GG, Kerendi F, Walters T, Fang Q, Deuse T, Beygui R, Lee RJ

Impact of Aortic Stenosis on Myofiber Stress: Translational Application of Left Ventricle-Aortic Coupling Simulation.

Frontiers in physiology

Wisneski AD, Wang Y, Deuse T, Hill AC, Pasta S, Sack KL, Yao J, Guccione JM

The H-Y Antigen in Embryonic Stem Cells Causes Rejection in Syngeneic Female Recipients.

Stem cells and development

Hu X, Kueppers ST, Kooreman NG, Gravina A, Wang D, Tediashvili G, Schlickeiser S, Frentsch M, Nikolaou C, Thiel A, Marcus S, Fuchs S, Velden J, Reichenspurner H, Volk HD, Deuse T, Schrepfer S

Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.

Seminars in thoracic and cardiovascular surgery

Kukreja J, Tsou S, Chen J, Trinh BN, Feng C, Golden JA, Hays S, Deuse T, Singer JP, Brzezinski M

Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.

Thorax

Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP

Impact of donor lung quality on post-transplant recipient outcome in the Lung Allocation Score era in Eurotransplant - a historical prospective study.

Transplant international : official journal of the European Society for Organ Transplantation

Smits JM, Gottlieb J, Verschuuren E, Evrard P, Hoek R, Knoop C, Lang G, Kwakkel-van Erp JM, Vos R, Verleden G, Rondelet B, Hoefer D, Langer F, Schramm R, Hoetzenecker K, van Kessel D, Luijk B, Seghers L, Deuse T, Buhl R, Witt C, Strelniece A, Green D, de Vries E, Laufer G, Van Raemdonck D

A Cryoinjury Model to Study Myocardial Infarction in the Mouse.

Journal of visualized experiments : JoVE

Wang D, Tediashvili G, Hu X, Gravina A, Marcus SG, Zhang H, Olgin JE, Deuse T, Schrepfer S

De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.

Nature biotechnology

Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, Weissman IL, Schrepfer S

Bergeyella cardium: Clinical Characteristics and Draft Genome of an Emerging Pathogen in Native and Prosthetic Valve Endocarditis.

Open forum infectious diseases

Mulliken JS, Langelier C, Budak JZ, Miller S, Dynerman D, Hao S, Li LM, Crawford E, Lyden A, Woodworth MH, DeRisi JL, Desmond E, Browne C, Luu A, Grandis DJ, Grossman W, Deuse T, Melcher GP

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients.

Nature biotechnology

Deuse T, Hu X, Gravina A, Wang D, Tediashvili G, De C, Thayer WO, Wahl A, Garcia JV, Reichenspurner H, Davis MM, Lanier LL, Schrepfer S

Analysis of Minimally Invasive Left Thoracotomy HVAD Implantation - A Single-Center Experience.

The Thoracic and cardiovascular surgeon

Reichart D, Brand CF, Bernhardt AM, Schmidt S, Schaefer A, Blankenberg S, Reichenspurner H, Wagner FM, Deuse T, Barten MJ

Lung allocation score: the Eurotransplant model versus the revised US model - a cross-sectional study.

Transplant international : official journal of the European Society for Organ Transplantation

Smits JM, Nossent G, Evrard P, Lang G, Knoop C, Kwakkel-van Erp JM, Langer F, Schramm R, van de Graaf E, Vos R, Verleden G, Rondelet B, Hoefer D, Hoek R, Hoetzenecker K, Deuse T, Strelniece A, Green D, de Vries E, Samuel U, Laufer G, Buhl R, Witt C, Gottlieb J

Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study.

The Lancet. Respiratory medicine

Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos D?ez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Les?che G, Thomas P, Tudorache I, K?hn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A

Hybrid Open Minimally Invasive Transcatheter Mitral Valve Replacement.

The Annals of thoracic surgery

Marcus SG, Mahadevan VS, Deuse T

Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta.

Journal of visualized experiments : JoVE

Tediashvili G, Wang D, Reichenspurner H, Deuse T, Schrepfer S

Hybrid and surgical procedures for the treatment of persistent and longstanding persistent atrial fibrillation.

Expert review of cardiovascular therapy

Sanchez JM, Al-Dosari G, Chu S, Beygui R, Deuse T, Badhwar N, Lee RJ

Outcomes of Minimally Invasive Temporary Right Ventricular Assist Device Support for Acute Right Ventricular Failure During Minimally Invasive Left Ventricular Assist Device Implantation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Schaefer A, Reichart D, Bernhardt AM, Kubik M, Barten MJ, Wagner FM, Reichenspurner H, Philipp SA, Deuse T

Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats - an experimental study.

Transplant international : official journal of the European Society for Organ Transplantation

Miller KK, Wang D, Hu X, Hua X, Deuse T, Neofytou E, Renne T, Velden J, Reichenspurner H, Schrepfer S, Bernstein D

Differences in Vascular Response between Balloon Overstretch and Stent Overexpansion in Nonatherosclerotic Porcine Coronary Arteries.

Comparative medicine

Mitsutake Y, Reifart J, Pyun WB, Lyons JK, Deuse T, Schrepfer S, Ikeno F

Gender differences and outcomes in left ventricular assist device support: The European Registry for Patients with Mechanical Circulatory Support.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Magnussen C, Bernhardt AM, Ojeda FM, Wagner FM, Gummert J, de By TMMH, Krabatsch T, Mohacsi P, Rybczynski M, Knappe D, Sill B, Deuse T, Blankenberg S, Schnabel RB, Reichenspurner H

The value of fluorine-18 deoxyglucose positron emission tomography scans in patients with ventricular assist device specific infections�.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

Bernhardt AM, Pamirsad MA, Brand C, Reichart D, Tienken M, Barten MJ, Schaefer A, Grahn H, Rybczynski M, Deuse T, Reichenspurner H, Wagner FM

Lobar lung transplantation from deceased donors: A systematic review.

World journal of transplantation

Eberlein M, Reed RM, Chahla M, Bolukbas S, Blevins A, Van Raemdonck D, Stanzi A, Inci I, Marasco S, Shigemura N, Aigner C, Deuse T

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency.

Journal of visualized experiments : JoVE

Wang D, Tediashvili G, Pecha S, Reichenspurner H, Deuse T, Schrepfer S

Orthotopic tracheal transplantation using human bronchus: an original xenotransplant model of obliterative airway disorder.

Transplant international : official journal of the European Society for Organ Transplantation

Guihaire J, Itagaki R, Stubbendorff M, Hua X, Deuse T, Ullrich S, Fadel E, Dorfm?ller P, Robbins RC, Reichenspurner H, Schumacher U, Schrepfer S

Acute Pulmonary Artery Obstruction as the Primary Manifestation of a Rapidly Growing Intimal Sarcoma in a 54-Year-Old Patient.

The Thoracic and cardiovascular surgeon reports

Westhofen S, Kugler C, Reichenspurner H, Deuse T

A matched pairs analysis of non-rib-spreading, fully endoscopic, mini-incision technique versus conventional mini-thoracotomy for mitral valve repair.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

Westhofen S, Conradi L, Deuse T, Detter C, Vettorazzi E, Treede H, Reichenspurner H

The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation.

Transplantation

Deuse T, Hua X, Stubbendorff M, Spin JM, Neofytou E, Taylor V, Chen Y, Park G, Fink JB, Renne T, Kiefmann M, Kiefmann R, Reichenspurner H, Robbins RC, Schrepfer S

The MANDELA study: A multicenter, randomized, open-label, parallel group trial to refine the use of everolimus after heart transplantation.

Contemporary clinical trials

Deuse T, Bara C, Barten MJ, Hirt SW, Doesch AO, Knosalla C, Grinninger C, Stypmann J, Garbade J, Wimmer P, May C, Porstner M, Schulz U

Local MicroRNA Modulation Using a Novel Anti-miR-21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis.

Arteriosclerosis, thrombosis, and vascular biology

Wang D, Deuse T, Stubbendorff M, Chernogubova E, Erben RG, Eken SM, Jin H, Li Y, Busch A, Heeger CH, Behnisch B, Reichenspurner H, Robbins RC, Spin JM, Tsao PS, Schrepfer S, Maegdefessel L

Immunobiology of fibrin-based engineered heart tissue.

Stem cells translational medicine

Conradi L, Schmidt S, Neofytou E, Deuse T, Peters L, Eder A, Hua X, Hansen A, Robbins RC, Beygui RE, Reichenspurner H, Eschenhagen T, Schrepfer S

Concomitant minimally invasive HVAD and transapical aortic valve implantation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Schaefer A, Treede H, Bernhardt A, Wagner FM, Reichenspurner H, Deuse T

SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts.

Cell stem cell

Deuse T, Wang D, Stubbendorff M, Itagaki R, Grabosch A, Greaves LC, Alawi M, Gr?newald A, Hu X, Hua X, Velden J, Reichenspurner H, Robbins RC, Jaenisch R, Weissman IL, Schrepfer S

Thymoglobulin induction in heart transplantation: patient selection and implications for maintenance immunosuppression.

Transplant international : official journal of the European Society for Organ Transplantation

Zuckermann A, Schulz U, Deuse T, Ruhpawar A, Schmitto JD, Beiras-Fernandez A, Hirt S, Schweiger M, Kopp-Fernandes L, Barten MJ

Isolated permanent right ventricular assist device implantation with the HeartWare continuous-flow ventricular assist device: first results from the European Registry for Patients with Mechanical Circulatory Support.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

Bernhardt AM, De By TM, Reichenspurner H, Deuse T

Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy.

Journal of cardiovascular electrophysiology

Pecha S, Wilke I, Bernhardt A, Hakmi S, Yildirim Y, Steven D, Reichenspurner H, Willems S, Deuse T, Aydin A

HVAD implantation in right atrium-to-right pulmonary artery configuration.

Artificial organs

Deuse T, Kubik M, Reichenspurner H

Introduction of the lung allocation score in Germany.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Gottlieb J, Greer M, Sommerwerck U, Deuse T, Witt C, Schramm R, Hagl C, Strueber M, Smits JM

Inducing myointimal hyperplasia versus atherosclerosis in mice: an introduction of two valid models.

Journal of visualized experiments : JoVE

Stubbendorff M, Hua X, Deuse T, Ali Z, Reichenspurner H, Maegdefessel L, Robbins RC, Schrepfer S

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury.

Nature

Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, Bola?os JP, Rakovic A, Spin JM, Stubbendorff M, Ikeno F, L?nger F, Zeller T, Schulte-Uentrop L, Stoehr A, Itagaki R, Haddad F, Eschenhagen T, Blankenberg S, Kiefmann R, Reichenspurner H, Velden J, Klein C, Yeung A, Robbins RC, Tsao PS, Schrepfer S

Minimally invasive implantation of biventricular assist devices.

The Thoracic and cardiovascular surgeon

Deuse T, Reichenspurner H

Do not touch the sternum--thoracotomy incisions for HVAD implantation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Deuse T, Reichenspurner H

Efficacy of prophylactic intra-aortic balloon pump therapy in chronic heart failure patients undergoing cardiac surgery.

Artificial organs

Yildirim Y, Pecha S, Kubik M, Alassar Y, Deuse T, Hakmi S, Reichenspurner H

Dual-chamber pacemaker implantation with left ventricular pacing in a patient with a right ventricular assist device.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Sill B, Reichenspurner H, Deuse T

HVAD continuous flow assist device for ischemic ventricular septal rupture.

The Journal of thoracic and cardiovascular surgery

Bernhardt AM, Reichenspurner H, Deuse T

Mechanically induced ventricular tachycardia by the HeartWare ventricular assist device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Yildirim Y, Pecha S, Reichenspurner H, Deuse T

Everolimus in heart transplantation: an update.

Journal of transplantation

Hirt SW, Bara C, Barten MJ, Deuse T, Doesch AO, Kaczmarek I, Schulz U, Stypmann J, Haneya A, Lehmkuhl HB

Bortezomib rescue therapy in a patient with recurrent antibody-mediated rejection after lung transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Baum C, Reichenspurner H, Deuse T

Granulocyte colony-stimulating factor therapy is associated with a reduced incidence of acute rejection episodes or allograft vasculopathy in heart transplant recipients.

Transplantation proceedings

Vrtovec B, Haddad F, Pham M, Deuse T, Fearon WF, Schrepfer S, Leon S, Vu T, Valantine H, Hunt SA

Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue.

Stem cells and development

Stubbendorff M, Deuse T, Hua X, Phan TT, Bieback K, Atkinson K, Eiermann TH, Velden J, Schr?der C, Reichenspurner H, Robbins RC, Volk HD, Schrepfer S

Minimal access median sternotomy for aortic valve replacement in elderly patients.

Journal of cardiothoracic surgery

Alassar Y, Yildirim Y, Pecha S, Detter C, Deuse T, Reichenspurner H

Isolated permanent right ventricular assistance using the HVAD continuous-flow pump.

The Annals of thoracic surgery

Deuse T, Schirmer J, Kubik M, Reichenspurner H

Aspergillus galactomannan antigen for diagnosis and treatment monitoring in cerebral aspergillosis.

Progress in transplantation (Aliso Viejo, Calif.)

Soeffker G, Wichmann D, Loderstaedt U, Sobottka I, Deuse T, Kluge S

The potassium channel KCa3.1 as new therapeutic target for the prevention of obliterative airway disease.

Transplantation

Hua X, Deuse T, Chen YJ, Wulff H, Stubbendorff M, K?hler R, Miura H, L?nger F, Reichenspurner H, Robbins RC, Schrepfer S

Severe bacterial superinfection based on influenza A (H1N1) pneumonia in a heart-lung transplant recipient.

The Thoracic and cardiovascular surgeon

Yildirim Y, Pecha S, Sill B, Deuse T, Reichenspurner H

Concomitant transcatheter aortic valve and left ventricular assist device implantation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Baum C, Seiffert M, Treede H, Reichenspurner H, Deuse T

Late profound muscle weakness following heart transplantation due to Danon disease.

Muscle & nerve

Van Der Starre P, Deuse T, Pritts C, Brun C, Vogel H, Oyer P

Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.

Transplantation

Deuse T, Hua X, Taylor V, Stubbendorff M, Baluom M, Chen Y, Park G, Velden J, Streichert T, Reichenspurner H, Robbins RC, Schrepfer S

Clinical and functional correlates of early microvascular dysfunction after heart transplantation.

Circulation. Heart failure

Haddad F, Khazanie P, Deuse T, Weisshaar D, Zhou J, Nam CW, Vu TA, Gomari FA, Skhiri M, Simos A, Schnittger I, Vrotvec B, Hunt SA, Fearon WF

Human internal mammary artery (IMA) transplantation and stenting: a human model to study the development of in-stent restenosis.

Journal of visualized experiments : JoVE

Hua X, Deuse T, Michelakis ED, Haromy A, Tsao PS, Maegdefessel L, Erben RG, Bergow C, Behnisch BB, Reichenspurner H, Robbins RC, Schrepfer S

Cardiac paraganglioma: diagnostic and surgical challenges.

Journal of cardiac surgery

Huo JL, Choi JC, DeLuna A, Lee D, Fleischmann D, Berry GJ, Deuse T, Haddad F

Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival.

Circulation

Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M, Tsao PS, Hua X, Velden J, Eiermann T, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S

Immunobiology of na�ve and genetically modified HLA-class-I-knockdown human embryonic stem cells.

Journal of cell science

Deuse T, Seifert M, Phillips N, Fire A, Tyan D, Kay M, Tsao PS, Hua X, Velden J, Eiermann T, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S

Surgical technique of lower lobe lung transplantation.

The Annals of thoracic surgery

Deuse T, Sill B, von Samson P, Yildirim Y, Kugler C, Oldigs M, Klose H, Meierling S, Rabe KF, Reichenspurner H

Bioluminescence imaging for assessment of immune responses following implantation of engineered heart tissue (EHT).

Journal of visualized experiments : JoVE

Conradi L, Pahrmann C, Schmidt S, Deuse T, Hansen A, Eder A, Reichenspurner H, Robbins RC, Eschenhagen T, Schrepfer S

Minimally invasive resection of a right atrial mass in a cardiac transplant recipient: a case report.

Transplantation proceedings

Conradi L, Deuse T, Treede H, Seiffert M, Adam M, Koelble K, Costard-Jaeckle A, Wagner FM, Reichenspurner H

Antibody response after a single dose of an AS03-adjuvanted split-virion influenza A (H1N1) vaccine in heart transplant recipients.

Transplantation

Meyer S, Adam M, Schweiger B, Ilchmann C, Eulenburg C, Sattinger E, Runte H, Schl?ter M, Deuse T, Reichenspurner H, Costard-J?ckle A

Orthotopic aortic transplantation: a rat model to study the development of chronic vasculopathy.

Journal of visualized experiments : JoVE

Stubbendorff M, Deuse T, Hammel A, Robbins RC, Reichenspurner H, Schrepfer S

Transcatheter aortic valve implantation in a heart transplant recipient: a case report.

Transplantation proceedings

Seiffert M, Meyer S, Franzen O, Conradi L, Baldus S, Schirmer J, Deuse T, Costard-Jaeckle A, Reichenspurner H, Treede H

Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells.

Cell transplantation

Deuse T, Stubbendorff M, Tang-Quan K, Phillips N, Kay MA, Eiermann T, Phan TT, Volk HD, Reichenspurner H, Robbins RC, Schrepfer S

Sustained inhibition of epsilon protein kinase C inhibits vascular restenosis after balloon injury and stenting.

Circulation

Deuse T, Koyanagi T, Erben RG, Hua X, Velden J, Ikeno F, Reichenspurner H, Robbins RC, Mochly-Rosen D, Schrepfer S

Review of heart-lung transplantation at Stanford.

The Annals of thoracic surgery

Deuse T, Sista R, Weill D, Tyan D, Haddad F, Dhillon G, Robbins RC, Reitz BA

Non-volume-loaded heart provides a more relevant heterotopic transplantation model.

Transplant immunology

Tang-Quan KR, Bartos J, Deuse T, Churchill E, Sch?fer H, Reichenspurner H, Mochly-Rosen D, Robbins RC, Schrepfer S

Heterotopic and orthotopic tracheal transplantation in mice used as models to study the development of obliterative airway disease.

Journal of visualized experiments : JoVE

Hua X, Deuse T, Tang-Quan KR, Robbins RC, Reichenspurner H, Schrepfer S

Asymptomatic infection with novel influenza A/H1N1 virus in a heart transplant recipient.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Meyer S, Ilchmann C, Adam M, Sattinger E, Siamkouris D, Arunagirinathan U, Deuse T, Wagner FM, Reichenspurner H, Costard-Jaeckle A

Mechanisms behind local immunosuppression using inhaled tacrolimus in preclinical models of lung transplantation.

American journal of respiratory cell and molecular biology

Deuse T, Blankenberg F, Haddad M, Reichenspurner H, Phillips N, Robbins RC, Schrepfer S

Changing trends in infectious disease in heart transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Haddad F, Deuse T, Pham M, Khazanie P, Rosso F, Luikart H, Valantine H, Leon S, Vu TA, Hunt SA, Oyer P, Montoya JG

LAD-ligation: a murine model of myocardial infarction.

Journal of visualized experiments : JoVE

Kolk MV, Meyberg D, Deuse T, Tang-Quan KR, Robbins RC, Reichenspurner H, Schrepfer S

Alternative technique for salvage of donor lungs with insufficient atrial cuffs.

The Annals of thoracic surgery

Yarbrough WM, Bates MJ, Deuse T, Tang DG, Robbins RC, Reitz BA, Mallidi HR

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.

Circulation

Deuse T, Peter C, Fedak PW, Doyle T, Reichenspurner H, Zimmermann WH, Eschenhagen T, Stein W, Wu JC, Robbins RC, Schrepfer S

Imaging in-stent restenosis: an inexpensive, reliable, and rapid preclinical model.

Journal of visualized experiments : JoVE

Deuse T, Ikeno F, Robbins RC, Schrepfer S

Heart-lung transplantation in situs inversus totalis.

The Annals of thoracic surgery

Deuse T, Reitz BA

Right ventricular dysfunction predicts poor outcome following hemodynamically compromising rejection.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Haddad F, Fisher P, Pham M, Berry G, Weisshaar D, Kuppahally S, Vrtovec B, Deuse T, Virani S, Fearon W, Valantine H, Hunt S

A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection.

Transplantation

Velotta JB, Deuse T, Haddad M, Masuda E, Park G, Carroll D, Taylor V, Robbins RC, Schrepfer S

Heart transplantation in situs inversus totalis.

The Journal of thoracic and cardiovascular surgery

Deuse T, Reitz BA

Twenty-year survivors of heart transplantation at Stanford University.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Deuse T, Haddad F, Pham M, Hunt S, Valantine H, Bates MJ, Mallidi HR, Oyer PE, Robbins RC, Reitz BA

Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection.

Transplantation

Deuse T, Velotta JB, Hoyt G, Govaert JA, Taylor V, Masuda E, Herlaar E, Park G, Carroll D, Pelletier MP, Robbins RC, Schrepfer S

Prevention and inhibition but not reversion of chronic allograft vasculopathy by FK778.

Transplantation

Deuse T, Hoyt G, Koyanagi T, Robbins RC, Schrepfer S

Introducing the first polymer-free leflunomide eluting stent.

Atherosclerosis

Deuse T, Erben RG, Ikeno F, Behnisch B, Boeger R, Connolly AJ, Reichenspurner H, Bergow C, Pelletier MP, Robbins RC, Schrepfer S

Fluoroscopy to assess late heart and lung perforation by a permanent ventricular pacemaker lead. A case complicated by isolated hemothorax.

International journal of cardiology

Mortensen K, Aydin MA, Goldmann B, Deuse T, Willems S, Ventura R

Effect of inhaled tacrolimus on cellular and humoral rejection to prevent posttransplant obliterative airway disease.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Schrepfer S, Deuse T, Reichenspurner H, Hoffmann J, Haddad M, Fink J, Fischbein MP, Robbins RC, Pelletier MP

Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection?

Transplantation proceedings

Deuse T, Schrepfer S, Pelletier MP, Fischbein MP, Robbins RC, Reichenspurner H

Stem cell transplantation: the lung barrier.

Transplantation proceedings

Schrepfer S, Deuse T, Reichenspurner H, Fischbein MP, Robbins RC, Pelletier MP

Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?

Transplant immunology

Deuse T, Schrepfer S, Reichenspurner H, Hoyt G, Fischbein MP, Robbins RC, Pelletier MP

Simplified protocol to isolate, purify, and culture expand mesenchymal stem cells.

Stem cells and development

Schrepfer S, Deuse T, Lange C, Katzenberg R, Reichenspurner H, Robbins RC, Pelletier MP

Experimental orthotopic tracheal transplantation: The Stanford technique.

Microsurgery

Schrepfer S, Deuse T, Hoyt G, Sheikh AY, Hoffmann J, Reichenspurner H, Robbins RC, Pelletier MP

FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Schrepfer S, Deuse T, Koch-Nolte F, Krieger T, Haddad M, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H

Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?

Cardiology

Schrepfer S, Deuse T, Sultan KR, Haddad M, Böger R, Münzel T, Schäfer H, Pelletier MP, Robbins RC, Reichenspurner H

The selective estrogen receptor-beta agonist biochanin A shows vasculoprotective effects without uterotrophic activity.

Menopause (New York, N.Y.)

Schrepfer S, Deuse T, Münzel T, Schäfer H, Braendle W, Reichenspurner H

Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.

Circulation

Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T

FK778: new cellular and molecular mechanisms of action.

Transplantation proceedings

Schrepfer S, Deuse T, Koch-Nolte F, Detter C, Reichenspurner H

Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.

Transplant international : official journal of the European Society for Organ Transplantation

Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schäfer H, Detter C, Reichenspurner H

Tracheal allograft transplantation in rats: the role of different immunosuppressants on preservation of respiratory epithelium.

Transplantation proceedings

Schrepfer S, Deuse T, Sydow K, Schäfer H, Detter C, Reichenspurner H

The phytoestrogen biochaninA weakens acute cardiac allograft rejection without affecting the reproductive system.

Transplant immunology

Schrepfer S, Deuse T, Schäfer H, Koch-Nolte F, Braendle W, Reichenspurner H

FK778 and tacrolimus prevent the development of obliterative airway disease after heterotopic rat tracheal transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Deuse T, Schrepfer S, Koch-Nolte F, Haddad M, Schwedhelm E, Böger R, Schäfer H, Detter C, Reichenspurner H

FK778, a novel immunosuppressive agent, reduces early adhesion molecule up-regulation and prolongs cardiac allograft survival.

Transplant international : official journal of the European Society for Organ Transplantation

Schrepfer S, Deuse T, Schäfer H, Reichenspurner H

Video and robotic-assisted minimally invasive mitral valve surgery: a comparison of the Port-Access and transthoracic clamp techniques.

The Annals of thoracic surgery

Reichenspurner H, Detter C, Deuse T, Boehm DH, Treede H, Reichart B

FK778 attenuates lymphocyte-endothelium interaction after cardiac transplantation: in vivo and in vitro studies.

Transplantation

Deuse T, Schrepfer S, Schäfer H, Koch-Nolte F, Schwedhelm E, Böger RH, Reichenspurner H

Successful resection of a symptomatic right ventricular lipoma.

The Annals of thoracic surgery

Schrepfer S, Deuse T, Detter C, Treede H, Koops A, Boehm DH, Willems S, Lacour-Gayet F, Reichenspurner H

Robotically assisted coronary artery bypass surgery with the ZEUS telemanipulator system.

Seminars in thoracic and cardiovascular surgery

Boehm DH, Detter C, Arnold MB, Deuse T, Reichenspurner H

Correlation between mononuclear infiltration and changes in VASP phosphorylation patterns after heterotopic cardiac transplantation in the rat.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes

Deuse T, Lange V, Schrepfer S, Eigenthaler M, Reichart B, Walter U, Elert O

New technique for chest opening in mice: U-sternotomy.

Microsurgery

Schrepfer S, Deuse T, Reichenspurner H

Midterm results and quality of life after minimally invasive vs. conventional aortic valve replacement.

The Thoracic and cardiovascular surgeon

Detter C, Deuse T, Boehm DH, Reichenspurner H, Reichart B

Comparison of two stabilizer concepts for off-pump coronary artery bypass grafting.

The Annals of thoracic surgery

Detter C, Deuse T, Christ F, Boehm DH, Reichenspurner H, Reichart B

Robotically-assisted coronary artery surgery with and without cardiopulmonary bypass - from first clinical use to endoscopic operation.

Medical science monitor : international medical journal of experimental and clinical research

Detter C, Boehm DH, Reichenspurner H, Deuse T, Arnold M, Reichart B

Effect of hemodynamics on graft rejection in the heterotopic heart transplantation model.

Transplantation proceedings

Lange V, Gassel AM, Deuse T, Ulrichs K, Silber RE