Morton Cowan, MD

Professor Emeritus
Pediatrics
+1 415 515-3075

Mort Cowan, MD studies the definitive treatment of children with primary immune deficiencies using hematopoietic stem cells while also running a first-in-human trial of lentiviral mediated gene insertion into autologous stem cells to correct the immune deficiency in Artemis-deficient Severe Combined Immunodeficiency (ART-SCID).

Publications: 

The ClinGen Severe Combined Immunodeficiency Disease Variant Curation Expert Panel: Specifications for classification of variants in ADA , DCLRE1C , IL2RG , IL7R , JAK3 , RAG1 , and RAG2.

medRxiv : the preprint server for health sciences

Jacovas VC, Zelnick M, McNulty S, Ross JE, Khurana N, Pan X, Nieto A, Martin S, McLean B, Elnagheeb MA, Cowan MJ, Puck JM, Hershfield M, Verbsky J, Walter J, Allenspach E, Chan AY, van Oers NSC, Ghosh R, Piazza M, Yuan B, Notarangelo LD, Johnson BA, Chinn IK

Younger Children with Non-Malignant Disease Have Increased Incidence of Mixed Myeloid Chimerism After Allogeneic Hematopoietic Cell Transplantation with Busulfan-Based Conditioning.

Transplantation and cellular therapy

Dvorak CC, Temple WC, Cisneros GS, Chu J, Winestone LE, Higham CS, Shimano KA, Kharbanda S, Avagyan S, Pauerstein P, Huang JN, Cheng G, Waters E, Winger BA, Cowan MJ, Long-Boyle JR

High symptom burden in female X-linked chronic granulomatous disease carriers.

Clinical immunology (Orlando, Fla.)

Miranda MA, Tsalatsanis A, Trotter JR, Arnold DE, Squire JD, Kidd S, Parikh S, Marsh RA, Griffith LM, Mallhi K, Chellapandian D, Lim SS, Grunebaum E, Sullivan KE, Newburger PE, Dinauer MC, Cowan MJ, Dvorak CC, Haddad E, Kohn DB, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Torgerson TR, Malech HL, Kang EM, Morton FB, Leiding JW

Relevance of lymphocyte proliferation to PHA in severe combined immunodeficiency (SCID) and T cell lymphopenia.

Clinical immunology (Orlando, Fla.)

Abraham RS, Basu A, Heimall JR, Dunn E, Yip A, Kapadia M, Kapoor N, Satter LF, Buckley R, O'Reilly R, Cuvelier GDE, Chandra S, Bednarski J, Chaudhury S, Moore TB, Haines H, Dávila Saldaña BJ, Chellapandian D, Rayes A, Chen K, Caywood E, Chandrakasan S, Lugt MTV, Ebens C, Teira P, Shereck E, Miller H, Aquino V, Eissa H, Yu LC, Gillio A, Madden L, Knutsen A, Shah AJ, DeSantes K, Barnum J, Broglie L, Joshi AY, Kleiner G, Dara J, Prockop S, Martinez C, Mousallem T, Oved J, Burroughs L, Marsh R, Torgerson TR, Leiding JW, Pai SY, Kohn DB, Pulsipher MA, Griffith LM, Notarangelo LD, Cowan MJ, Puck J, Dvorak CC, Haddad E

Allogeneic hematopoietic cell transplantation is effective for p47phox chronic granulomatous disease: a PIDTC study.

The Journal of allergy and clinical immunology

Grunebaum E, Arnold DE, Logan B, Parikh S, Marsh RA, Griffith LM, Mallhi K, Chellapandian D, Lim SS, Deal CL, Kapoor N, Murguía-Favela L, Falcone EL, Prasad VK, Touzot F, Bleesing JJ, Chandrakasan S, Heimall JR, Bednarski JJ, Broglie LA, Chong HJ, Kapadia M, Prockop S, Dávila Saldaña BJ, Schaefer E, Bauchat AL, Teira P, Chandra S, Parta M, Cowan MJ, Dvorak CC, Haddad E, Kohn DB, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Torgerson T, Malech HL, Kang EM, Leiding JW

Genotype, Oxidase Status, and Preceding Infection or Autoinflammation Do Not Affect Allogeneic HCT Outcomes for CGD.

Blood

Leiding JW, Arnold DE, Parikh SH, Logan BR, Marsh RA, Griffith LM, Wu R, Kidd S, Mallhi KK, Chellapandian D, Si Lim S, Grunebaum E, Falcone EL, Murguia-Favela L, Grossman D, Prasad VK, Heimall JR, Touzot F, Burroughs L, Bleesing J, Kapoor N, Dara J, Williams O, Kapadia M, Oshrine BR, Bednarski JJ, Rayes A, Chong H, Cuvelier GDE, Forbes Satter LR, Martinez C, Vander Lugt MT, Yu LC, Chandrakasan S, Joshi A, Prockop SE, Dávila Saldaña BJ, Aquino V, Broglie L, Ebens CL, Madden LM, DeSantes K, Milner J, Rangarajan HG, Shah A, Gilio AP, Knutsen AP, Miller HK, Moore TB, Graham P, Bauchat A, Bunin NJ, Teira P, Petrovic A, Chandra S, Abdel-Azim H, Dorsey M, Birbrayer O, Cowan MJ, Dvorak CC, Haddad E, Kohn DB, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Torgerson TR, Malech HL, Kang EM

Integrome signatures of lentiviral gene therapy for SCID-X1 patients.

Science advances

Yan KK, Condori J, Ma Z, Metais JY, Ju B, Ding L, Dhungana Y, Palmer LE, Langfitt DM, Ferrara F, Throm R, Shi H, Risch I, Bhatara S, Shaner B, Lockey TD, Talleur AC, Easton J, Meagher MM, Puck JM, Cowan MJ, Zhou S, Mamcarz E, Gottschalk S, Yu J

Post-Transplant Late Complications Increase Over Time for Patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) Landmark Study.

The Journal of allergy and clinical immunology

Eissa H, Thakar M, Shah AJ, Logan B, Griffith LM, Dong H, Parrott RE, O'Reilly R, Dara J, Kapoor N, Satter LF, Chandra S, Kapadia M, Chandrakasan S, Knutsen A, Jyonouchi SC, Molinari L, Rayes A, Ebens CL, Teira P, Dávila Saldaña BJ, Burroughs LM, Chaudhury S, Chellapandian D, Gillio AP, Goldman F, Malech HL, DeSantes K, Cuvelier GDE, Rozmus J, Quinones R, Yu LC, Broglie L, Aquino V, Shereck E, Moore TB, Lugt MV, Mousallem TI, Oved JH, Dorsey M, Azim HA, Martinez C, Bleesing J, Prockop S, Kohn DB, Bednarski JJ, Leiding J, Marsh RA, Torgerson T, Notarangelo LD, Pai SY, Pulsipher MA, Puck JM, Dvorak CC, Haddad E, Buckley RH, Cowan MJ, Heimall J

Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease.

The Journal of allergy and clinical immunology

Chandrasekaran P, Han Y, Zerbe CS, Heller T, DeRavin SS, Kreuzberg SA, Marciano BE, Siu Y, Jones DR, Abraham RS, Stephens MC, Tsou AM, Snapper S, Conlan S, Subramanian P, Quinones M, Grou C, Calderon V, Deming C, Leiding JW, Arnold DE, Logan BR, Griffith LM, Petrovic A, Mousallem TI, Kapoor N, Heimall JR, Barnum JL, Kapadia M, Wright N, Rayes A, Chandra S, Broglie LA, Chellapandian D, Deal CL, Grunebaum E, Lim SS, Mallhi K, Marsh RA, Murguia-Favela L, Parikh S, Touzot F, Cowan MJ, Dvorak CC, Haddad E, Kohn DB, Notarangelo L, Pai SY, Puck JM, Pulsipher MA, Torgerson TR, Kang EM, Malech HL, Segre JA, Bryant CE, Holland SM, Falcone EL

Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium.

Lancet (London, England)

Thakar MS, Logan BR, Puck JM, Dunn EA, Buckley RH, Cowan MJ, O'Reilly RJ, Kapoor N, Satter LF, Pai SY, Heimall J, Chandra S, Ebens CL, Chellapandian D, Williams O, Burroughs LM, Saldana BD, Rayes A, Madden LM, Chandrakasan S, Bednarski JJ, DeSantes KB, Cuvelier GDE, Teira P, Gillio AP, Eissa H, Knutsen AP, Goldman FD, Aquino VM, Shereck EB, Moore TB, Caywood EH, Lugt MTV, Rozmus J, Broglie L, Yu LC, Shah AJ, Andolina JR, Liu X, Parrott RE, Dara J, Prockop S, Martinez CA, Kapadia M, Jyonouchi SC, Sullivan KE, Bleesing JJ, Chaudhury S, Petrovic A, Keller MD, Quigg TC, Parikh S, Shenoy S, Seroogy C, Rubin T, Decaluwe H, Routes JM, Torgerson TR, Leiding JW, Pulsipher MA, Kohn DB, Griffith LM, Haddad E, Dvorak CC, Notarangelo LD

Hypomorphic RAG deficiency: impact of disease burden on survival and thymic recovery argues for early diagnosis and HSCT.

Blood

Schuetz C, Gerke J, Ege MJ, Walter JE, Kusters M, Worth AJJ, Kanakry JA, Dimitrova D, Wolska-Kusnierz B, Chen K, Unal E, Karakukcu M, Pashchenko O, Leiding JW, Kawai T, Amrolia PJ, Berghuis D, Buechner J, Buchbinder D, Cowan MJ, Gennery AR, G?ng?r T, Heimall JR, Miano M, Meyts I, Morris EC, Rivi?re JG, Sharapova SO, Shaw PJ, Slatter MA, Honig M, Veys P, Fischer A, Cavazzana M, Moshous D, Schulz AS, Albert MH, Puck JM, Lankester AC, Notarangelo LD, Neven B

Successful TCRa�/CD19-Depleted Hematopoietic Cell Transplantation for a Patient With Artemis Deficiency.

Journal of pediatric hematology/oncology

Tomomasa D, Isoda T, Mitsuiki N, Inoue K, Nishimura A, Uda K, Uchiyama T, Yamashita M, Kamiya T, Endo A, Takagi M, Imai K, Kajiwara M, Cowan MJ, Morio T, Kanegane H

Lentiviral Gene Therapy for Artemis-Deficient SCID.

The New England journal of medicine

Cowan MJ, Yu J, Facchino J, Fraser-Browne C, Sanford U, Kawahara M, Dara J, Long-Boyle J, Oh J, Chan W, Chag S, Broderick L, Chellapandian D, Decaluwe H, Golski C, Hu D, Kuo CY, Miller HK, Petrovic A, Currier R, Hilton JF, Punwani D, Dvorak CC, Malech HL, McIvor RS, Puck JM

Impact of Genetic Diagnosis on the Outcome of Hematopoietic Stem Cell Transplant in Primary Immunodeficiency Disorders.

Journal of clinical immunology

Forlanini F, Chan A, Dara J, Dvorak CC, Cowan MJ, Puck JM, Dorsey MJ

The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions.

The Journal of allergy and clinical immunology

Dvorak CC, Haddad E, Heimall J, Dunn E, Buckley RH, Kohn DB, Cowan MJ, Pai SY, Griffith LM, Cuvelier GDE, Eissa H, Shah AJ, O'Reilly RJ, Pulsipher MA, Wright NAM, Abraham RS, Satter LF, Notarangelo LD, Puck JM

The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions.

The Journal of allergy and clinical immunology

Dvorak CC, Haddad E, Heimall J, Dunn E, Cowan MJ, Pai SY, Kapoor N, Satter LF, Buckley RH, O'Reilly RJ, Chandra S, Bednarski JJ, Williams O, Rayes A, Moore TB, Ebens CL, Davila Saldana BJ, Petrovic A, Chellapandian D, Cuvelier GDE, Vander Lugt MT, Caywood EH, Chandrakasan S, Eissa H, Goldman FD, Shereck E, Aquino VM, Desantes KB, Madden LM, Miller HK, Yu L, Broglie L, Gillio A, Shah AJ, Knutsen AP, Andolina JP, Joshi AY, Szabolcs P, Kapadia M, Martinez CA, Parrot RE, Sullivan KE, Prockop SE, Abraham RS, Thakar MS, Leiding JW, Kohn DB, Pulsipher MA, Griffith LM, Notarangelo LD, Puck JM

Clinical and Genetic Characterization of Patients with Artemis Deficiency in Japan.

Journal of clinical immunology

Inoue K, Miyamoto S, Tomomasa D, Adachi E, Azumi S, Horikoshi Y, Ishihara T, Osone S, Kawahara Y, Kudo K, Kato Z, Ohnishi H, Kashimada K, Imai K, Ohara O, van Zelm MC, Cowan MJ, Morio T, Kanegane H

Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC.

Blood

Cuvelier GDE, Logan BR, Prockop SE, Buckley RH, Kuo CY, Griffith LM, Liu X, Yip A, Hershfield MS, Ayoub PG, Moore TB, Dorsey MJ, O'Reilly RJ, Kapoor N, Pai SY, Kapadia M, Ebens CL, Forbes Satter LR, Burroughs LM, Petrovic A, Chellapandian D, Heimall J, Shyr DC, Rayes A, Bednarski JJ, Chandra S, Chandrakasan S, Gillio AP, Madden L, Quigg TC, Caywood EH, D?vila Salda?a BJ, DeSantes K, Eissa H, Goldman FD, Rozmus J, Shah AJ, Vander Lugt MT, Thakar MS, Parrott RE, Martinez C, Leiding JW, Torgerson TR, Pulsipher MA, Notarangelo LD, Cowan MJ, Dvorak CC, Haddad E, Puck JM, Kohn DB

Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation.

The Journal of allergy and clinical immunology

Labrosse R, Boufaied I, Bourdin B, Gona S, Randolph HE, Logan BR, Bourbonnais S, Berthe C, Chan W, Buckley RH, Parrott RE, Cuvelier GDE, Kapoor N, Chandra S, D?vila Salda?a BJ, Eissa H, Goldman FD, Heimall J, O'Reilly R, Chaudhury S, Kolb EA, Shenoy S, Griffith LM, Pulsipher M, Kohn DB, Notarangelo LD, Pai SY, Cowan MJ, Dvorak CC, Haddad ?, Puck JM, Barreiro LB, Decaluwe H

Lentivector cryptic splicing mediates increase in CD34+ clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency.

Nature communications

De Ravin SS, Liu S, Sweeney CL, Brault J, Whiting-Theobald N, Ma M, Liu T, Choi U, Lee J, O'Brien SA, Quackenbush P, Estwick T, Karra A, Docking E, Kwatemaa N, Guo S, Su L, Sun Z, Zhou S, Puck J, Cowan MJ, Notarangelo LD, Kang E, Malech HL, Wu X

Granulocyte Transfusions in Patients with Chronic Granulomatous Disease Undergoing Hematopoietic Cell Transplantation or Gene Therapy.

Journal of clinical immunology

Arnold DE, Chellapandian D, Parikh S, Mallhi K, Marsh RA, Heimall JR, Grossman D, Chitty-Lopez M, Murguia-Favela L, Gennery AR, Boulad F, Arbuckle E, Cowan MJ, Dvorak CC, Griffith LM, Haddad E, Kohn DB, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Torgerson T, Kang EM, Malech HL, Leiding JW

Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation.

Transplantation and cellular therapy

Bogn?r T, Bartelink IH, Egberts TCG, Rademaker CMA, Versluys AB, Slatter MA, Kletzel M, Nath CE, Cuvelier GDE, Savic RM, Dvorak C, Long-Boyle JR, Cowan MJ, Bittencourt H, Bredius RGM, G?ng?r T, Shaw PJ, Ansari M, Hassan M, Krajinovic M, Hempel G, Marktel S, Chiesa R, Th?oret Y, Lund T, Orchard PJ, Wynn RF, Boelens JJ, Lalmohamed A

Quantitative brain MRI morphology in severe and attenuated forms of mucopolysaccharidosis type I.

Molecular genetics and metabolism

Kovac V, Shapiro EG, Rudser KD, Mueller BA, Eisengart JB, Delaney KA, Ahmed A, King KE, Yund BD, Cowan MJ, Raiman J, Mamak EG, Harmatz PR, Shankar SP, Ali N, Cagle SR, Wozniak JR, Lim KO, Orchard PJ, Whitley CB, Nestrasil I

Poor T-cell receptor � repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution.

The Journal of allergy and clinical immunology

Delmonte OM, Castagnoli R, Yu J, Dvorak CC, Cowan MJ, D?vila Salda?a BJ, De Ravin SS, Mamcarz E, Chang CK, Daley SR, Griffith LM, Notarangelo LD, Puck JM

Expectations and experience: Parent and patient perspectives regarding treatment for Severe Combined Immunodeficiency (SCID).

Clinical immunology (Orlando, Fla.)

Smith H, Scalchunes C, Cowan MJ, Puck J, Heimall J

Correction to: Infections in Infants with SCID: Isolation, Infection Screening and Prophylaxis in PIDTC Centers.

Journal of clinical immunology

Dorsey M, Wright NAM, Chaimowitz NS, D?vila Salda?a BJ, Miller H, Keller MD, Thakar MS, Shah AJ, Abu-Arja R, Andolina J, Aquino V, Barnum JL, Bednarski JJ, Bhatia M, Bonilla FA, Butte MJ, Bunin NJ, Burroughs LM, Chandra S, Chaudhury S, Chen K, Chong H, Cuvelier G, Dalal J, DeFelice ML, DeSantes KB, Forbes LR, Gillio A, Goldman F, Joshi AY, Kapoor N, Knutsen AP, Kobrynski L, Lieberman JA, Leiding JW, Oshrine B, Patel KP, Prockop S, Quigg TC, Quinones R, Schultz KR, Seroogy C, Shyr D, Siegel S, Smith AR, Torgerson TR, Vander Lugt MT, Yu LC, Cowan MJ, Buckley RH, Dvorak CC, Griffith LM, Haddad E, Kohn DB, Logan B, Notarangelo LD, Pai SY, Puck J, Pulsipher MA, Heimall J

The Relationship Between Busulfan Exposure and Achievement of Sustained Donor Myeloid Chimerism in Patients with Non-Malignant Disorders.

Transplantation and cellular therapy

Apsel Winger B, Shukla P, Kharbanda S, Keizer RJ, Goswami S, Cowan MJ, Dvorak CC, Long-Boyle J

Unknown cytomegalovirus serostatus in primary immunodeficiency disorders: A new category of transplant recipients.

Transplant infectious disease : an official journal of the Transplantation Society

Forlanini F, Dara J, Dvorak CC, Cowan MJ, Puck JM, Dorsey MJ

Correction: Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT.

Journal of clinical immunology

Marsh RA, Leiding JW, Logan BR, Griffith LM, Arnold DE, Haddad E, Falcone EL, Yin Z, Patel K, Arbuckle E, Bleesing JJ, Sullivan KE, Heimall J, Burroughs LM, Skoda-Smith S, Chandrakasan S, Yu LC, Oshrine BR, Cuvelier GDE, Thakar MS, Chen K, Teira P, Shenoy S, Phelan R, Forbes LR, Martinez C, Chellapandian D, D?vila Salda?a BJ, Shah AJ, Weinacht KG, Joshi A, Boulad F, Quigg TC, Dvorak CC, Grossman D, Torgerson T, Graham P, Prasad V, Knutsen A, Chong H, Miller H, de la Morena MT, DeSantes K, Cowan MJ, Notarangelo LD, Kohn DB, Stenger E, Pai SY, Routes JM, Puck JM, Kapoor N, Pulsipher MA, Malech HL, Parikh S, Kang EM, submitted on behalf of the Primary Immune Deficiency Treatment Consortium

Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers.

Journal of clinical immunology

Dorsey MJ, Wright NAM, Chaimowitz NS, D?vila Salda?a BJ, Miller H, Keller MD, Thakar MS, Shah AJ, Abu-Arja R, Andolina J, Aquino V, Barnum JL, Bednarski JJ, Bhatia M, Bonilla FA, Butte MJ, Bunin NJ, Chandra S, Chaudhury S, Chen K, Chong H, Cuvelier GDE, Dalal J, DeFelice ML, DeSantes KB, Forbes LR, Gillio A, Goldman F, Joshi AY, Kapoor N, Knutsen AP, Kobrynski L, Lieberman JA, Leiding JW, Oshrine B, Patel KP, Prockop S, Quigg TC, Quinones R, Schultz KR, Seroogy C, Shyr D, Siegel S, Smith AR, Torgerson TR, Vander Lugt MT, Yu LC, Cowan MJ, Buckley RH, Dvorak CC, Griffith LM, Haddad E, Kohn DB, Logan B, Notarangelo LD, Pai SY, Puck J, Pulsipher MA, Heimall J

Successful SCID gene therapy in infant with disseminated BCG.

The journal of allergy and clinical immunology. In practice

Maron G, Kaste S, Bahrami A, Neel M, Malech HL, Puck JM, Cowan MJ, Gottschalk S, Mamcarz E

Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID) in the US Immunodeficiency Network (USIDNet) Registry.

Journal of clinical immunology

Kuo CY, Garabedian E, Puck J, Cowan MJ, Sullivan KE, Buckley RH, Cunningham-Rundles C, Marsh R, Candotti F, Kohn DB

Reduced Toxicity Conditioning for Nonmalignant Hematopoietic Cell Transplants.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Contreras CF, Long-Boyle JR, Shimano KA, Melton A, Kharbanda S, Dara J, Higham C, Huang JN, Cowan MJ, Dvorak CC

Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report.

Blood

Burroughs LM, Petrovic A, Brazauskas R, Liu X, Griffith LM, Ochs HD, Bleesing JJ, Edwards S, Dvorak CC, Chaudhury S, Prockop SE, Quinones R, Goldman FD, Quigg TC, Chandrakasan S, Smith AR, Parikh S, D?vila Salda?a BJ, Thakar MS, Phelan R, Shenoy S, Forbes LR, Martinez C, Chellapandian D, Shereck E, Miller HK, Kapoor N, Barnum JL, Chong H, Shyr DC, Chen K, Abu-Arja R, Shah AJ, Weinacht KG, Moore TB, Joshi A, DeSantes KB, Gillio AP, Cuvelier GDE, Keller MD, Rozmus J, Torgerson T, Pulsipher MA, Haddad E, Sullivan KE, Logan BR, Kohn DB, Puck JM, Notarangelo LD, Pai SY, Rawlings DJ, Cowan MJ

Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey.

Frontiers in immunology

Chan AY, Leiding JW, Liu X, Logan BR, Burroughs LM, Allenspach EJ, Skoda-Smith S, Uzel G, Notarangelo LD, Slatter M, Gennery AR, Smith AR, Pai SY, Jordan MB, Marsh RA, Cowan MJ, Dvorak CC, Craddock JA, Prockop SE, Chandrakasan S, Kapoor N, Buckley RH, Parikh S, Chellapandian D, Oshrine BR, Bednarski JJ, Cooper MA, Shenoy S, Davila Saldana BJ, Forbes LR, Martinez C, Haddad E, Shyr DC, Chen K, Sullivan KE, Heimall J, Wright N, Bhatia M, Cuvelier GDE, Goldman FD, Meyts I, Miller HK, Seidel MG, Vander Lugt MT, Bacchetta R, Weinacht KG, Andolina JR, Caywood E, Chong H, de la Morena MT, Aquino VM, Shereck E, Walter JE, Dorsey MJ, Seroogy CM, Griffith LM, Kohn DB, Puck JM, Pulsipher MA, Torgerson TR

Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT.

Journal of clinical immunology

Marsh RA, Leiding JW, Logan BR, Griffith LM, Arnold DE, Haddad E, Falcone EL, Yin Z, Patel K, Arbuckle E, Bleesing JJ, Sullivan KE, Heimall J, Burroughs LM, Skoda-Smith S, Chandrakasan S, Yu LC, Oshrine BR, Cuvelier GDE, Thakar MS, Chen K, Teira P, Shenoy S, Phelan R, Forbes LR, Chellapandian D, D?vila Salda?a BJ, Shah AJ, Weinacht KG, Joshi A, Boulad F, Quigg TC, Dvorak CC, Grossman D, Torgerson T, Graham P, Prasad V, Knutsen A, Chong H, Miller H, de la Morena MT, DeSantes K, Cowan MJ, Notarangelo LD, Kohn DB, Stenger E, Pai SY, Routes JM, Puck JM, Kapoor N, Pulsipher MA, Malech HL, Parikh S, Kang EM, submitted on behalf of the Primary Immune Deficiency Treatment Consortium

Psychosocial services for primary immunodeficiency disorder families during hematopoietic cell transplantation: A descriptive study.

Palliative & supportive care

Mangurian C, Scalchunes C, Yoo J, Logan B, Henderson T, Iyengar S, Smith H, Cowan MJ

Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1.

The New England journal of medicine

Mamcarz E, Zhou S, Lockey T, Abdelsamed H, Cross SJ, Kang G, Ma Z, Condori J, Dowdy J, Triplett B, Li C, Maron G, Aldave Becerra JC, Church JA, Dokmeci E, Love JT, da Matta Ain AC, van der Watt H, Tang X, Janssen W, Ryu BY, De Ravin SS, Weiss MJ, Youngblood B, Long-Boyle JR, Gottschalk S, Meagher MM, Malech HL, Puck JM, Cowan MJ, Sorrentino BP

Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Dvorak CC, Long-Boyle J, Dara J, Melton A, Shimano KA, Huang JN, Puck JM, Dorsey MJ, Facchino J, Chang CK, Cowan MJ

Newborn Screening for Severe Combined Immunodeficiency and T-cell Lymphopenia in California, 2010-2017.

Pediatrics

Amatuni GS, Currier RJ, Church JA, Bishop T, Grimbacher E, Nguyen AA, Agarwal-Hashmi R, Aznar CP, Butte MJ, Cowan MJ, Dorsey MJ, Dvorak CC, Kapoor N, Kohn DB, Markert ML, Moore TB, Naides SJ, Sciortino S, Feuchtbaum L, Koupaei RA, Puck JM

Hematopoietic stem cell transplantation for CD40 ligand deficiency: Results from an EBMT/ESID-IEWP-SCETIDE-PIDTC study.

The Journal of allergy and clinical immunology

Ferrua F, Galimberti S, Courteille V, Slatter MA, Booth C, Moshous D, Neven B, Blanche S, Cavazzana M, Laberko A, Shcherbina A, Balashov D, Soncini E, Porta F, Al-Mousa H, Al-Saud B, Al-Dhekri H, Arnaout R, Formankova R, Bertrand Y, Lange A, Smart J, Wolska-Kusnierz B, Aquino VM, Dvorak CC, Fasth A, Fouyssac F, Heilmann C, Hoenig M, Schuetz C, Kelecic J, Bredius RGM, Lankester AC, Lindemans CA, Suarez F, Sullivan KE, Albert MH, Kalwak K, Barlogis V, Bhatia M, Bordon V, Czogala W, Alonso L, Dogu F, Gozdzik J, Ikinciogullari A, Kriv?n G, Ljungman P, Meyts I, Mustillo P, Smith AR, Speckmann C, Sundin M, Keogh SJ, Shaw PJ, Boelens JJ, Schulz AS, Sedlacek P, Veys P, Mahlaoui N, Janda A, Davies EG, Fischer A, Cowan MJ, Gennery AR, SCETIDE, PIDTC, EBMT & ESID IEWP

Supporting caregivers during hematopoietic cell transplantation for children with primary immunodeficiency disorders.

The Journal of allergy and clinical immunology

Yoo J, Halley MC, Lown EA, Yank V, Ort K, Cowan MJ, Dorsey MJ, Smith H, Iyengar S, Scalchunes C, Mangurian C

The genetic landscape of severe combined immunodeficiency in the United States and Canada in the current era (2010-2018).

The Journal of allergy and clinical immunology

Dvorak CC, Haddad E, Buckley RH, Cowan MJ, Logan B, Griffith LM, Kohn DB, Pai SY, Notarangelo L, Shearer W, Prockop S, Kapoor N, Heimall J, Chaudhury S, Shyr D, Chandra S, Cuvelier G, Moore T, Shenoy S, Goldman F, Smith AR, Sunkersett G, Vander Lugt M, Caywood E, Quigg T, Torgerson T, Chandrakasan S, Craddock J, D?vila Salda?a BJ, Gillio A, Shereck E, Aquino V, DeSantes K, Knutsen A, Thakar M, Yu L, Puck JM

Advances and highlights in primary immunodeficiencies in 2017.

The Journal of allergy and clinical immunology

Chinen J, Cowan MJ

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.

Blood

Haddad E, Logan BR, Griffith LM, Buckley RH, Parrott RE, Prockop SE, Small TN, Chaisson J, Dvorak CC, Murnane M, Kapoor N, Abdel-Azim H, Hanson IC, Martinez C, Bleesing JJH, Chandra S, Smith AR, Cavanaugh ME, Jyonouchi S, Sullivan KE, Burroughs L, Skoda-Smith S, Haight AE, Tumlin AG, Quigg TC, Taylor C, D?vila Salda?a BJ, Keller MD, Seroogy CM, Desantes KB, Petrovic A, Leiding JW, Shyr DC, Decaluwe H, Teira P, Gillio AP, Knutsen AP, Moore TB, Kletzel M, Craddock JA, Aquino V, Davis JH, Yu LC, Cuvelier GDE, Bednarski JJ, Goldman FD, Kang EM, Shereck E, Porteus MH, Connelly JA, Fleisher TA, Malech HL, Shearer WT, Szabolcs P, Thakar MS, Vander Lugt MT, Heimall J, Yin Z, Pulsipher MA, Pai SY, Kohn DB, Puck JM, Cowan MJ, O'Reilly RJ, Notarangelo LD

Application of a radiosensitivity flow assay in a patient with DNA ligase 4 deficiency.

Blood advances

Buchbinder D, Smith MJ, Kawahara M, Cowan MJ, Buzby JS, Abraham RS

Allograft and patient survival after sequential HSCT and kidney transplantation from the same donor-A multicenter analysis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Eder M, Schwarz C, Kammer M, Jacobsen N, Stavroula ML, Cowan MJ, Chongkrairatanakul T, Gaston R, Ravanan R, Ishida H, Bachmann A, Alvarez S, Koch M, Garrouste C, Duffner UA, Cullis B, Schaap N, Medinger M, Sørensen SS, Dauber EM, Böhmig G, Regele H, Berlakovich GA, Wekerle T, Oberbauer R

Outcome of domino hematopoietic stem cell transplantation in human subjects: An international case series.

The Journal of allergy and clinical immunology

Belderbos ME, Gennery AR, Dvorak CC, Blok HJ, Eikema DJ, Silva JMF, Veys P, Neven B, Buckley R, Cole T, Cowan MJ, Goebel WS, Hoenig M, Kuo CY, Stiehm ER, Wynn R, Bierings M, Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation and the Prima

B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation.

Blood

Miggelbrink AM, Logan BR, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, Abdel-Azim H, Prockop SE, Shyr D, Decaluwe H, Hanson IC, Gillio A, D?vila Salda?a BJ, Eibel H, Hopkins G, Walter JE, Whangbo JS, Kohn DB, Puck JM, Cowan MJ, Griffith LM, Haddad E, O'Reilly RJ, Notarangelo LD, Pai SY

Donor lymphocyte infusion and methotrexate for immune recovery after T-cell depleted haploidentical transplantation.

American journal of hematology

Gilman AL, Leung W, Cowan MJ, Cannon M, Epstein S, Barnhart C, Shah K, Hyland M, Fukes T, Ivanova A

Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study.

Blood

Heimall J, Logan BR, Cowan MJ, Notarangelo LD, Griffith LM, Puck JM, Kohn DB, Pulsipher MA, Parikh S, Martinez C, Kapoor N, O'Reilly R, Boyer M, Pai SY, Goldman F, Burroughs L, Chandra S, Kletzel M, Thakar M, Connelly J, Cuvelier G, Davila Saldana BJ, Shereck E, Knutsen A, Sullivan KE, DeSantes K, Gillio A, Haddad E, Petrovic A, Quigg T, Smith AR, Stenger E, Yin Z, Shearer WT, Fleisher T, Buckley RH, Dvorak CC

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Frontiers in immunology

Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, Chou J, Daza-Cajigal V, Ott de Bruin LM, de la Morena MT, Di Matteo G, Finocchi A, Geha R, Goyal RK, Hayward A, Holland S, Huang CH, Kanariou MG, King A, Kaplan B, Kleva A, Kuijpers TW, Lee BW, Lougaris V, Massaad M, Meyts I, Morsheimer M, Neven B, Pai SY, Parvaneh N, Plebani A, Prockop S, Reisli I, Soh JY, Somech R, Torgerson TR, Kim YJ, Walter JE, Gennery AR, Keles S, Manis JP, Marcenaro E, Moretta A, Parolini S, Notarangelo LD

Long term outcomes of severe combined immunodeficiency: therapy implications.

Expert review of clinical immunology

Heimall J, Cowan MJ

Neurologic event-free survival demonstrates a benefit for SCID patients diagnosed by newborn screening.

Blood advances

Dvorak CC, Puck JM, Wahlstrom JT, Dorsey M, Melton A, Cowan MJ

Opening Marrow Niches in Patients Undergoing Autologous Hematopoietic Stem Cell Gene Therapy.

Hematology/oncology clinics of North America

Cowan MJ, Dvorak CC, Long-Boyle J

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Frontiers in immunology

Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, Chou J, Daza-Cajigal V, Ott de Bruin LM, de la Morena M, Di Matteo G, Finocchi A, Geha R, Goyal RK, Hayward A, Holland S, Huang CH, Kanariou MG, King A, Kaplan B, Kleva A, Kuijpers TW, Lee BW, Lougaris V, Massaad M, Meyts I, Morsheimer M, Neven B, Pai SY, Parvaneh N, Plebani A, Prockop S, Reisli I, Soh JY, Somech R, Torgerson TR, Kim YJ, Walter JE, Gennery AR, Keles S, Manis JP, Marcenaro E, Moretta A, Parolini S, Notarangelo LD

Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Ivaturi V, Dvorak CC, Chan D, Liu T, Cowan MJ, Wahlstrom J, Stricherz M, Jennissen C, Orchard PJ, Tolar J, Pai SY, Huang L, Aweeka F, Long-Boyle J

Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium Inter

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Heimall J, Buckley RH, Puck J, Fleisher TA, Gennery AR, Haddad E, Neven B, Slatter M, Roderick S, Baker KS, Dietz AC, Duncan C, Griffith LM, Notarangelo L, Pulsipher MA, Cowan MJ

Hematopoietic Stem Cell Transplantation Activity in Pediatric Cancer between 2008 and 2014 in the United States: A Center for International Blood and Marrow Transplant Research Report.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Khandelwal P, Millard HR, Thiel E, Abdel-Azim H, Abraham AA, Auletta JJ, Boulad F, Brown VI, Camitta BM, Chan KW, Chaudhury S, Cowan MJ, Angel-Diaz M, Gadalla SM, Gale RP, Hale G, Kasow KA, Keating AK, Kitko CL, MacMillan ML, Olsson RF, Page KM, Seber A, Smith AR, Warwick AB, Wirk B, Mehta PA

Unconditioned unrelated donor bone marrow transplantation for IL7Rα- and Artemis-deficient SCID.

Bone marrow transplantation

Dvorak CC, Patel K, Puck JM, Wahlstrom J, Dorsey MJ, Adams R, Facchino J, Cowan MJ

Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders.

The Journal of allergy and clinical immunology

Slack J, Albert MH, Balashov D, Belohradsky BH, Bertaina A, Bleesing J, Booth C, Buechner J, Buckley RH, Ouach?e-Chardin M, Deripapa E, Drabko K, Eapen M, Feuchtinger T, Finocchi A, Gaspar HB, Ghosh S, Gillio A, Gonzalez-Granado LI, Grunebaum E, G?ng?r T, Heilmann C, Helminen M, Higuchi K, Imai K, Kalwak K, Kanazawa N, Karasu G, Kucuk ZY, Laberko A, Lange A, Mahlaoui N, Meisel R, Moshous D, Muramatsu H, Parikh S, Pasic S, Schmid I, Schuetz C, Schulz A, Schultz KR, Shaw PJ, Slatter MA, Sykora KW, Tamura S, Taskinen M, Wawer A, Wolska-Kusnierz B, Cowan MJ, Fischer A, Gennery AR, Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation and the Eur, Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE), Center for International Blood and Marrow Transplant Research, Primary Immunodeficiency Treatment Consortium

Reticular dysgenesis: international survey on clinical presentation, transplantation, and outcome.

Blood

Hoenig M, Lagresle-Peyrou C, Pannicke U, Notarangelo LD, Porta F, Gennery AR, Slatter M, Cowan MJ, Stepensky P, Al-Mousa H, Al-Zahrani D, Pai SY, Al Herz W, Gaspar HB, Veys P, Oshima K, Imai K, Yabe H, Noroski LM, Wulffraat NM, Sykora KW, Soler-Palacin P, Muramatsu H, Al Hilali M, Moshous D, Debatin KM, Schuetz C, Jacobsen EM, Schulz AS, Schwarz K, Fischer A, Friedrich W, Cavazzana M, European Society for Blood and Marrow Transplantation (EBMT) Inborn Errors Working Party

Treatment of infants identified as having severe combined immunodeficiency by means of newborn screening.

The Journal of allergy and clinical immunology

Dorsey MJ, Dvorak CC, Cowan MJ, Puck JM

Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B.

The New England journal of medicine

Punwani D, Zhang Y, Yu J, Cowan MJ, Rana S, Kwan A, Adhikari AN, Lizama CO, Mendelsohn BA, Fahl SP, Chellappan A, Srinivasan R, Brenner SE, Wiest DL, Puck JM

Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.

The Journal of clinical investigation

Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B, Chen K, Lee YN, Tirosh I, Dobbs K, Al-Herz W, Cowan MJ, Puck J, Bleesing JJ, Grimley MS, Malech H, De Ravin SS, Gennery AR, Abraham RS, Joshi AY, Boyce TG, Butte MJ, Nadeau KC, Balboni I, Sullivan KE, Akhter J, Adeli M, El-Feky RA, El-Ghoneimy DH, Dbaibo G, Wakim R, Azzari C, Palma P, Cancrini C, Capuder K, Condino-Neto A, Costa-Carvalho BT, Oliveira JB, Roifman C, Buchbinder D, Kumanovics A, Franco JL, Niehues T, Schuetz C, Kuijpers T, Yee C, Chou J, Masaad MJ, Geha R, Uzel G, Gelman R, Holland SM, Recher M, Utz PJ, Browne SK, Notarangelo LD

Devouring the Hematopoietic Stem Cell: Setting the Table for Marrow Cell Transplantation.

Molecular therapy : the journal of the American Society of Gene Therapy

Cowan MJ, Kiem HP

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

The Lancet. Haematology

Bartelink IH, Lalmohamed A, van Reij EM, Dvorak CC, Savic RM, Zwaveling J, Bredius RG, Egberts AC, Bierings M, Kletzel M, Shaw PJ, Nath CE, Hempel G, Ansari M, Krajinovic M, Th?or?t Y, Duval M, Keizer RJ, Bittencourt H, Hassan M, G?ng?r T, Wynn RF, Veys P, Cuvelier GD, Marktel S, Chiesa R, Cowan MJ, Slatter MA, Stricherz MK, Jennissen C, Long-Boyle JR, Boelens JJ

The Second Pediatric Blood and Marrow Transplant Consortium International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Defining the Unique Late Effects of Children Undergoing Hematopoietic Cell Transplantation f

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Dietz AC, Duncan CN, Alter BP, Bresters D, Cowan MJ, Notarangelo L, Rosenberg PS, Shenoy S, Skinner R, Walters MC, Wagner J, Baker KS, Pulsipher MA

Lentivirus Mediated Correction of Artemis-Deficient Severe Combined Immunodeficiency.

Human gene therapy

Punwani D, Kawahara M, Yu J, Sanford U, Roy S, Patel K, Carbonaro DA, Karlen AD, Khan S, Cornetta K, Rothe M, Schambach A, Kohn DB, Malech HL, McIvor RS, Puck JM, Cowan MJ

Unrelated Hematopoietic Cell Transplantation in a Patient with Combined Immunodeficiency with Granulomatous Disease and Autoimmunity Secondary to RAG Deficiency.

Journal of clinical immunology

John T, Walter JE, Schuetz C, Chen K, Abraham RS, Bonfim C, Boyce TG, Joshi AY, Kang E, Carvalho BT, Mahajerin A, Nugent D, Puthenveetil G, Soni A, Su H, Cowan MJ, Notarangelo L, Buchbinder D

Evaluation of Pre-Hematopoietic Cell Transplantation (HCT) Brain MRI and Neurologic Complications of Pediatric Patients Undergoing HCT for Hematologic Malignancies.

Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses

Bailey-Olson M, Cowan M, Dvorak C, Mueller S, Owens A, Wahlstrom J, Horn B

Severe, persistent, and fatal T-cell immunodeficiency following therapy for infantile leukemia.

Pediatric blood & cancer

Geerlinks AV, Issekutz T, Wahlstrom JT, Sullivan KE, Cowan MJ, Dvorak CC, Fernandez CV

Transplacental maternal engraftment and posttransplantation graft-versus-host disease in children with severe combined immunodeficiency.

The Journal of allergy and clinical immunology

Wahlstrom J, Patel K, Eckhert E, Kong D, Horn B, Cowan MJ, Dvorak CC

Primary Immune Deficiency Treatment Consortium (PIDTC) update.

The Journal of allergy and clinical immunology

Griffith LM, Cowan MJ, Notarangelo LD, Kohn DB, Puck JM, Shearer WT, Burroughs LM, Torgerson TR, Decaluwe H, Haddad E, workshop participants

Safe and Effective Prophylaxis with Bimonthly Intravenous Pentamidine in the Pediatric Hematopoietic Stem Cell Transplant Population.

The Pediatric infectious disease journal

Levy ER, Musick L, Zinter MS, Lang T, Cowan MJ, Weintrub PS, Dvorak CC

A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.

The Journal of experimental medicine

Chan AY, Punwani D, Kadlecek TA, Cowan MJ, Olson JL, Mathes EF, Sunderam U, Fu SM, Srinivasan R, Kuriyan J, Brenner SE, Weiss A, Puck JM

Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.

The Journal of clinical investigation

Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B, Chen K, Lee YN, Tirosh I, Dobbs K, Al-Herz W, Cowan MJ, Puck J, Bleesing JJ, Grimley MS, Malech H, De Ravin SS, Gennery AR, Abraham RS, Joshi AY, Boyce TG, Butte MJ, Nadeau KC, Balboni I, Sullivan KE, Akhter J, Adeli M, El-Feky RA, El-Ghoneimy DH, Dbaibo G, Wakim R, Azzari C, Palma P, Cancrini C, Capuder K, Condino-Neto A, Costa-Carvalho BT, Oliveira JB, Roifman C, Buchbinder D, Kumanovics A, Franco JL, Niehues T, Schuetz C, Kuijpers T, Yee C, Chou J, Masaad MJ, Geha R, Uzel G, Gelman R, Holland SM, Recher M, Utz PJ, Browne SK, Notarangelo LD

New Insights Into Multicenter PICU Mortality Among Pediatric Hematopoietic Stem Cell Transplant Patients.

Critical care medicine

Zinter MS, Dvorak CC, Spicer A, Cowan MJ, Sapru A

Neurocognition across the spectrum of mucopolysaccharidosis type I: Age, severity, and treatment.

Molecular genetics and metabolism

Shapiro EG, Nestrasil I, Rudser K, Delaney K, Kovac V, Ahmed A, Yund B, Orchard PJ, Eisengart J, Niklason GR, Raiman J, Mamak E, Cowan MJ, Bailey-Olson M, Harmatz P, Shankar SP, Cagle S, Ali N, Steiner RD, Wozniak J, Lim KO, Whitley CB

Role of transgene regulation in ex vivo lentiviral correction of artemis deficiency.

Human gene therapy

Multhaup MM, Podetz-Pedersen KM, Karlen AD, Olson ER, Gunther R, Somia NV, Blazar BR, Cowan MJ, McIvor RS

Successful newborn screening for SCID in the Navajo Nation.

Clinical immunology (Orlando, Fla.)

Kwan A, Hu D, Song M, Gomes H, Brown DR, Bourque T, Gonzalez-Espinosa D, Lin Z, Cowan MJ, Puck JM

Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency.

Current pediatrics reports

Wahlstrom JT, Dvorak CC, Cowan MJ

Chimerism-based pre-emptive immunotherapy with fast withdrawal of immunosuppression and donor lymphocyte infusions after allogeneic stem cell transplantation for pediatric hematologic malignancies.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Horn B, Petrovic A, Wahlstrom J, Dvorak CC, Kong D, Hwang J, Expose-Spencer J, Gates M, Cowan MJ

Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation.

Journal of clinical immunology

Punwani D, Wang H, Chan AY, Cowan MJ, Mallott J, Sunderam U, Mollenauer M, Srinivasan R, Brenner SE, Mulder A, Claas FH, Weiss A, Puck JM

Stem cell transplantation for primary immunodeficiency diseases: the North American experience.

Current opinion in allergy and clinical immunology

Pai SY, Cowan MJ

Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.

JAMA

Kwan A, Abraham RS, Currier R, Brower A, Andruszewski K, Abbott JK, Baker M, Ballow M, Bartoshesky LE, Bonilla FA, Brokopp C, Brooks E, Caggana M, Celestin J, Church JA, Comeau AM, Connelly JA, Cowan MJ, Cunningham-Rundles C, Dasu T, Dave N, De La Morena MT, Duffner U, Fong CT, Forbes L, Freedenberg D, Gelfand EW, Hale JE, Hanson IC, Hay BN, Hu D, Infante A, Johnson D, Kapoor N, Kay DM, Kohn DB, Lee R, Lehman H, Lin Z, Lorey F, Abdel-Mageed A, Manning A, McGhee S, Moore TB, Naides SJ, Notarangelo LD, Orange JS, Pai SY, Porteus M, Rodriguez R, Romberg N, Routes J, Ruehle M, Rubenstein A, Saavedra-Matiz CA, Scott G, Scott PM, Secord E, Seroogy C, Shearer WT, Siegel S, Silvers SK, Stiehm ER, Sugerman RW, Sullivan JL, Tanksley S, Tierce ML, Verbsky J, Vogel B, Walker R, Walkovich K, Walter JE, Wasserman RL, Watson MS, Weinberg GA, Weiner LB, Wood H, Yates AB, Puck JM, Bonagura VR

Comparison of outcomes of hematopoietic stem cell transplantation without chemotherapy conditioning by using matched sibling and unrelated donors for treatment of severe combined immunodeficiency.

The Journal of allergy and clinical immunology

Dvorak CC, Hassan A, Slatter MA, H?nig M, Lankester AC, Buckley RH, Pulsipher MA, Davis JH, G?ng?r T, Gabriel M, Bleesing JH, Bunin N, Sedlacek P, Connelly JA, Crawford DF, Notarangelo LD, Pai SY, Hassid J, Veys P, Gennery AR, Cowan MJ

Transplantation outcomes for severe combined immunodeficiency, 2000-2009.

The New England journal of medicine

Pai SY, Logan BR, Griffith LM, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, Hanson IC, Filipovich AH, Jyonouchi S, Sullivan KE, Small TN, Burroughs L, Skoda-Smith S, Haight AE, Grizzle A, Pulsipher MA, Chan KW, Fuleihan RL, Haddad E, Loechelt B, Aquino VM, Gillio A, Davis J, Knutsen A, Smith AR, Moore TB, Schroeder ML, Goldman FD, Connelly JA, Porteus MH, Xiang Q, Shearer WT, Fleisher TA, Kohn DB, Puck JM, Notarangelo LD, Cowan MJ, O'Reilly RJ

Survey on retransplantation criteria for patients with severe combined immunodeficiency.

The Journal of allergy and clinical immunology

Haddad E, Allakhverdi Z, Griffith LM, Cowan MJ, Notarangelo LD

Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: the Primary Immune Deficiency Treatment Consortium experience.

The Journal of allergy and clinical immunology

Shearer WT, Dunn E, Notarangelo LD, Dvorak CC, Puck JM, Logan BR, Griffith LM, Kohn DB, O'Reilly RJ, Fleisher TA, Pai SY, Martinez CA, Buckley RH, Cowan MJ

SCID patients with ARTEMIS vs RAG deficiencies following HCT: increased risk of late toxicity in ARTEMIS-deficient SCID.

Blood

Schuetz C, Neven B, Dvorak CC, Leroy S, Ege MJ, Pannicke U, Schwarz K, Schulz AS, Hoenig M, Sparber-Sauer M, Gatz SA, Denzer C, Blanche S, Moshous D, Picard C, Horn BN, de Villartay JP, Cavazzana M, Debatin KM, Friedrich W, Fischer A, Cowan MJ

Primary Immune Deficiency Treatment Consortium (PIDTC) report.

The Journal of allergy and clinical immunology

Griffith LM, Cowan MJ, Notarangelo LD, Kohn DB, Puck JM, Pai SY, Ballard B, Bauer SC, Bleesing JJ, Boyle M, Brower A, Buckley RH, van der Burg M, Burroughs LM, Candotti F, Cant AJ, Chatila T, Cunningham-Rundles C, Dinauer MC, Dvorak CC, Filipovich AH, Fleisher TA, Bobby Gaspar H, Gungor T, Haddad E, Hovermale E, Huang F, Hurley A, Hurley M, Iyengar S, Kang EM, Logan BR, Long-Boyle JR, Malech HL, McGhee SA, Modell F, Modell V, Ochs HD, O'Reilly RJ, Parkman R, Rawlings DJ, Routes JM, Shearer WT, Small TN, Smith H, Sullivan KE, Szabolcs P, Thrasher A, Torgerson TR, Veys P, Weinberg K, Zuniga-Pflucker JC, workshop participants

Effect of weight and maturation on busulfan clearance in infants and small children undergoing hematopoietic cell transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Savic RM, Cowan MJ, Dvorak CC, Pai SY, Pereira L, Bartelink IH, Boelens JJ, Bredius RG, Wynn RF, Cuvelier GD, Shaw PJ, Slatter MA, Long-Boyle J

The missing vital sign.

BMJ (Clinical research ed.)

Mangurian C, Cowan MJ

The natural history of children with severe combined immunodeficiency: baseline features of the first fifty patients of the primary immune deficiency treatment consortium prospective study 6901.

Journal of clinical immunology

Dvorak CC, Cowan MJ, Logan BR, Notarangelo LD, Griffith LM, Puck JM, Kohn DB, Shearer WT, O'Reilly RJ, Fleisher TA, Pai SY, Hanson IC, Pulsipher MA, Fuleihan R, Filipovich A, Goldman F, Kapoor N, Small T, Smith A, Chan KW, Cuvelier G, Heimall J, Knutsen A, Loechelt B, Moore T, Buckley RH

Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California: results of the first 2 years.

The Journal of allergy and clinical immunology

Kwan A, Church JA, Cowan MJ, Agarwal R, Kapoor N, Kohn DB, Lewis DB, McGhee SA, Moore TB, Stiehm ER, Porteus M, Aznar CP, Currier R, Lorey F, Puck JM

A 32-Year-Old Female with AIDS, Pneumocystis jiroveci Pneumonia, and Methemoglobinemia.

Case reports in critical care

Giangreco GJ, Campbell D, Cowan MJ

The global cardiovascular risk transition: associations of four metabolic risk factors with national income, urbanization, and Western diet in 1980 and 2008.

Circulation

Danaei G, Singh GM, Paciorek CJ, Lin JK, Cowan MJ, Finucane MM, Farzadfar F, Stevens GA, Riley LM, Lu Y, Rao M, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group

Inequalities in non-communicable diseases and effective responses.

Lancet (London, England)

Di Cesare M, Khang YH, Asaria P, Blakely T, Cowan MJ, Farzadfar F, Guerrero R, Ikeda N, Kyobutungi C, Msyamboza KP, Oum S, Lynch JW, Marmot MG, Ezzati M, Lancet NCD Action Group

Nonpharmacologic approach to minimizing shivering during surface cooling: a proof of principle study.

Journal of critical care

Shah NG, Cowan MJ, Pickering E, Sareh H, Afshar M, Fox D, Marron J, Davis J, Herold K, Shanholtz CB, Hasday JD

Busulfan, fludarabine, and alemtuzumab as a reduced toxicity regimen for children with malignant and nonmalignant diseases improves engraftment and graft-versus-host disease without delaying immune reconstitution.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Law J, Cowan MJ, Dvorak CC, Musick L, Long-Boyle JR, Baxter-Lowe LA, Horn B

Adoptive immunotherapy with CMV-specific cytotoxic T lymphocytes for stem cell transplant patients with refractory CMV infections.

Journal of immunotherapy (Hagerstown, Md. : 1997)

Bao L, Cowan MJ, Dunham K, Horn B, McGuirk J, Gilman A, Lucas KG

Long-term survival and late deaths after hematopoietic cell transplantation for primary immunodeficiency diseases and inborn errors of metabolism.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Eapen M, Ahn KW, Orchard PJ, Cowan MJ, Davies SM, Fasth A, Hassebroek A, Ayas M, Bonfim C, O'Brien TA, Gross TG, Horwitz M, Horwitz E, Kapoor N, Kurtzberg J, Majhail N, Ringden O, Szabolcs P, Veys P, Baker KS

Massage for children undergoing hematopoietic cell transplantation: a qualitative report.

Evidence-based complementary and alternative medicine : eCAM

Ackerman SL, Lown EA, Dvorak CC, Dunn EA, Abrams DI, Horn BN, Degelman M, Cowan MJ, Mehling WE

Hematopoietic cell transplant and use of massage for improved symptom management: results from a pilot randomized control trial.

Evidence-based complementary and alternative medicine : eCAM

Mehling WE, Lown EA, Dvorak CC, Cowan MJ, Horn BN, Dunn EA, Acree M, Abrams DI, Hecht FM

IL-21 is the primary common ? chain-binding cytokine required for human B-cell differentiation in vivo.

Blood

Recher M, Berglund LJ, Avery DT, Cowan MJ, Gennery AR, Smart J, Peake J, Wong M, Pai SY, Baxi S, Walter JE, Palendira U, Tangye GA, Rice M, Brothers S, Al-Herz W, Oettgen H, Eibel H, Puck JM, Cattaneo F, Ziegler JB, Giliani S, Tangye SG, Notarangelo LD

T cell and B Cell immunity can be reconstituted with mismatched hematopoietic stem cell transplantation without alkylator therapy in artemis-deficient mice using anti-natural killer cell antibody and photochemically treated sensitized donor T cells.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Xiao TZ, Singh K, Dunn E, Ramachandran R, Cowan MJ

Genotype, phenotype, and outcomes of nine patients with T-B+NK+ SCID.

Pediatric transplantation

Yu GP, Nadeau KC, Berk DR, de Saint Basile G, Lambert N, Knapnougel P, Roberts J, Kavanau K, Dunn E, Stiehm ER, Lewis DB, Umetsu DT, Puck JM, Cowan MJ

Hematopoietic stem cell transplantation for CD3d deficiency.

The Journal of allergy and clinical immunology

Marcus N, Takada H, Law J, Cowan MJ, Gil J, Regueiro JR, Plaza Lopez de Sabando D, Lopez-Granados E, Dalal J, Friedrich W, Manfred H, Hanson IC, Grunebaum E, Shearer WT, Roifman CM

Physical activity in 22 African countries: results from the World Health Organization STEPwise approach to chronic disease risk factor surveillance.

American journal of preventive medicine

Guthold R, Louazani SA, Riley LM, Cowan MJ, Bovet P, Damasceno A, Sambo BH, Tesfaye F, Armstrong TP

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2�7 million participants.

Lancet (London, England)

Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Glucose)

Characterization of the human artemis promoter by heterologous gene expression in vitro and in vivo.

DNA and cell biology

Multhaup MM, Gurram S, Podetz-Pedersen KM, Karlen AD, Swanson DL, Somia NV, Hackett PB, Cowan MJ, McIvor RS

Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study.

Blood

Moratto D, Giliani S, Bonfim C, Mazzolari E, Fischer A, Ochs HD, Cant AJ, Thrasher AJ, Cowan MJ, Albert MH, Small T, Pai SY, Haddad E, Lisa A, Hambleton S, Slatter M, Cavazzana-Calvo M, Mahlaoui N, Picard C, Torgerson TR, Burroughs L, Koliski A, Neto JZ, Porta F, Qasim W, Veys P, Kavanau K, H?nig M, Schulz A, Friedrich W, Notarangelo LD

Malignancies after hematopoietic cell transplantation for primary immune deficiencies: a report from the Center for International Blood and Marrow Transplant Research.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Kamani NR, Kumar S, Hassebroek A, Eapen M, LeRademacher J, Casper J, Cowan M, S?nchez de Toledo J, Ferster A, Szabolcs P, Wingard JR, Horwitz E, Filipovich AH

Allogeneic hematopoietic SCT for alpha-mannosidosis: an analysis of 17 patients.

Bone marrow transplantation

Mynarek M, Tolar J, Albert MH, Escolar ML, Boelens JJ, Cowan MJ, Finnegan N, Glomstein A, Jacobsohn DA, K?hl JS, Yabe H, Kurtzberg J, Malm D, Orchard PJ, Klein C, L?cke T, Sykora KW

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9�1 million participants.

Lancet (London, England)

Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index)

National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 country-years and 3�0 million participants.

Lancet (London, England)

Farzadfar F, Finucane MM, Danaei G, Pelizzari PM, Cowan MJ, Paciorek CJ, Singh GM, Lin JK, Stevens GA, Riley LM, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Cholesterol)

National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5�4 million participants.

Lancet (London, England)

Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, Ezzati M, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure)

Chronic granulomatous disease: lessons from a rare disorder.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Segal BH, Veys P, Malech H, Cowan MJ

HLA-matched sibling bone marrow transplantation for �-thalassemia major.

Blood

Sabloff M, Chandy M, Wang Z, Logan BR, Ghavamzadeh A, Li CK, Irfan SM, Bredeson CN, Cowan MJ, Gale RP, Hale GA, Horan J, Hongeng S, Eapen M, Walters MC

X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease.

Blood

Booth C, Gilmour KC, Veys P, Gennery AR, Slatter MA, Chapel H, Heath PT, Steward CG, Smith O, O'Meara A, Kerrigan H, Mahlaoui N, Cavazzana-Calvo M, Fischer A, Moshous D, Blanche S, Pachlopnik Schmid J, Pachlopnick-Schmid J, Latour S, de Saint-Basile G, Albert M, Notheis G, Rieber N, Strahm B, Ritterbusch H, Lankester A, Hartwig NG, Meyts I, Plebani A, Soresina A, Finocchi A, Pignata C, Cirillo E, Bonanomi S, Peters C, Kalwak K, Pasic S, Sedlacek P, Jazbec J, Kanegane H, Nichols KE, Hanson IC, Kapoor N, Haddad E, Cowan M, Choo S, Smart J, Arkwright PD, Gaspar HB

Cytotoxicity associated with artemis overexpression after lentiviral vector-mediated gene transfer.

Human gene therapy

Multhaup M, Karlen AD, Swanson DL, Wilber A, Somia NV, Cowan MJ, McIvor RS

Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.

The Journal of experimental medicine

Walter JE, Rucci F, Patrizi L, Recher M, Regenass S, Paganini T, Keszei M, Pessach I, Lang PA, Poliani PL, Giliani S, Al-Herz W, Cowan MJ, Puck JM, Bleesing J, Niehues T, Schuetz C, Malech H, DeRavin SS, Facchetti F, Gennery AR, Andersson E, Kamani NR, Sekiguchi J, Alenezi HM, Chinen J, Dbaibo G, ElGhazali G, Fontana A, Pasic S, Detre C, Terhorst C, Alt FW, Notarangelo LD

Prostaglandin E2 potentiates heat shock-induced heat shock protein 72 expression in A549 cells.

Prostaglandins & other lipid mediators

Shah NG, Tulapurkar ME, Singh IS, Shelhamer JH, Cowan MJ, Hasday JD

Physical activity and sedentary behavior among schoolchildren: a 34-country comparison.

The Journal of pediatrics

Guthold R, Cowan MJ, Autenrieth CS, Kann L, Riley LM

Reduced-intensity conditioning regimens for allogeneic transplantation in children with acute lymphoblastic leukemia.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Verneris MR, Eapen M, Duerst R, Carpenter PA, Burke MJ, Afanasyev BV, Cowan MJ, He W, Krance R, Li CK, Tan PL, Wagner JE, Davies SM

Safety of the live, attenuated varicella vaccine in pediatric recipients of hematopoietic SCTs.

Bone marrow transplantation

Kussmaul SC, Horn BN, Dvorak CC, Abramovitz L, Cowan MJ, Weintrub PS

Radiosensitive severe combined immunodeficiency disease.

Immunology and allergy clinics of North America

Dvorak CC, Cowan MJ

Advancement of pediatric blood and marrow transplantation research in North America: priorities of the Pediatric Blood and Marrow Transplant Consortium.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Pulsipher MA, Horwitz EM, Haight AE, Kadota R, Chen AR, Frangoul H, Cooper LJ, Jacobsohn DA, Goyal RK, Mitchell D, Nieder ML, Yanik G, Cowan MJ, Soni S, Gardner S, Shenoy S, Taylor D, Cairo M, Schultz KR

Improving cellular therapy for primary immune deficiency diseases: recognition, diagnosis, and management.

The Journal of allergy and clinical immunology

Griffith LM, Cowan MJ, Notarangelo LD, Puck JM, Buckley RH, Candotti F, Conley ME, Fleisher TA, Gaspar HB, Kohn DB, Ochs HD, O'Reilly RJ, Rizzo JD, Roifman CM, Small TN, Shearer WT, Workshop Participants

Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Dvorak CC, Cowan MJ, Horn B, Weintrub PS

Clinical and immunologic outcomes following haplocompatible donor lymphocyte infusions.

Bone marrow transplantation

Dvorak CC, Gilman AL, Horn B, Jaroscak J, Dunn EA, Baxter-Lowe LA, Cowan MJ

A non-leaky Artemis-deficient mouse that accurately models the human severe combined immune deficiency phenotype, including resistance to hematopoietic stem cell transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Xiao Z, Dunn E, Singh K, Khan IS, Yannone SM, Cowan MJ

Airway management in children with mucopolysaccharidoses.

Archives of otolaryngology--head & neck surgery

Yeung AH, Cowan MJ, Horn B, Rosbe KW

Infusion of cytomegalovirus specific cytotoxic T lymphocytes from a sero-negative donor can facilitate resolution of infection and immune reconstitution.

The Pediatric infectious disease journal

Horn B, Bao L, Dunham K, Stamer M, Adler S, Cowan M, Lucas K

Wiskott-Aldrich syndrome: diagnosis, clinical and laboratory manifestations, and treatment.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Ochs HD, Filipovich AH, Veys P, Cowan MJ, Kapoor N

The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation.

Blood

Ringdén O, Pavletic SZ, Anasetti C, Barrett AJ, Wang T, Wang D, Antin JH, Di Bartolomeo P, Bolwell BJ, Bredeson C, Cairo MS, Gale RP, Gupta V, Hahn T, Hale GA, Halter J, Jagasia M, Litzow MR, Locatelli F, Marks DI, McCarthy PL, Cowan MJ, Petersdorf EW, Russell JA, Schiller GJ, Schouten H, Spellman S, Verdonck LF, Wingard JR, Horowitz MM, Arora M

Allogeneic hematopoietic cell transplantation for primary immune deficiency diseases: current status and critical needs.

The Journal of allergy and clinical immunology

Griffith LM, Cowan MJ, Kohn DB, Notarangelo LD, Puck JM, Schultz KR, Buckley RH, Eapen M, Kamani NR, O'Reilly RJ, Parkman R, Roifman CM, Sullivan KE, Filipovich AH, Fleisher TA, Shearer WT

Feasibility study of preemptive withdrawal of immunosuppression based on chimerism testing in children undergoing myeloablative allogeneic transplantation for hematologic malignancies.

Bone marrow transplantation

Horn B, Soni S, Khan S, Petrovic A, Breslin N, Cowan M, Pelle-Day G, Cooperstein E, Baxter-Lowe LA

Megadose CD34(+) cell grafts improve recovery of T cell engraftment but not B cell immunity in patients with severe combined immunodeficiency disease undergoing haplocompatible nonmyeloablative transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Dvorak CC, Hung GY, Horn B, Dunn E, Oon CY, Cowan MJ

Maternal T-cell engraftment associated with severe hemophagocytosis of the bone marrow in untreated X-linked severe combined immunodeficiency.

Journal of pediatric hematology/oncology

Dvorak CC, Sandford A, Fong A, Cowan MJ, George TI, Lewis DB

Hematopoietic stem cell transplantation for severe combined immunodeficiency diseases.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Cowan MJ, Neven B, Cavazanna-Calvo M, Fischer A, Puck J

Hematopoietic cell transplantation for Chediak-Higashi syndrome.

Bone marrow transplantation

Eapen M, DeLaat CA, Baker KS, Cairo MS, Cowan MJ, Kurtzberg J, Steward CG, Veys PA, Filipovich AH

Index of suspicion.

Pediatrics in review

Taylor Z, Butani L, Blumberg D, Cowan M, Wara D, Gopal S, Gavrilita C, Da-Silva S

Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease.

The Journal of biological chemistry

Povirk LF, Zhou T, Zhou R, Cowan MJ, Yannone SM

Reduced intensity conditioning using intravenous busulfan, fludarabine and rabbit ATG for children with nonmalignant disorders and CML.

Bone marrow transplantation

Horn B, Baxter-Lowe LA, Englert L, McMillan A, Quinn M, Desantes K, Cowan M

Two-tiered universal newborn screening strategy for severe combined immunodeficiency.

Molecular genetics and metabolism

McGhee SA, Stiehm ER, Cowan M, Krogstad P, McCabe ER

B7.2-/- mature dendritic cells generate T-helper 2 and regulatory T donor cells in fetal mice after in utero allogeneic bone marrow transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Bhattacharyya S, Cowan MJ

Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation.

Journal of immunology (Baltimore, Md. : 1950)

Li L, Salido E, Zhou Y, Bhattacharyya S, Yannone SM, Dunn E, Meneses J, Feeney AJ, Cowan MJ

Simian immunodeficiency virus infection of hematopoietic stem cells and bone marrow stromal cells.

Journal of acquired immune deficiency syndromes (1999)

Lee CI, Cowan MJ, Kohn DB, Tarantal AF

A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans.

Journal of immunology (Baltimore, Md. : 1950)

Li L, Moshous D, Zhou Y, Wang J, Xie G, Salido E, Hu D, de Villartay JP, Cowan MJ

Target dose adjustment of busulfan in pediatric patients undergoing bone marrow transplantation.

Bone marrow transplantation

Bolinger AM, Zangwill AB, Slattery JT, Risler LJ, Sultan DH, Glidden DV, Norstad D, Cowan MJ

Cutaneous manifestations of maternal engraftment in patients with severe combined immunodeficiency: a clinicopathologic study.

Bone marrow transplantation

Denianke KS, Frieden IJ, Cowan MJ, Williams ML, McCalmont TH

Bone marrow transplantation for T-B- severe combined immunodeficiency disease in Athabascan-speaking native Americans.

Bone marrow transplantation

O'Marcaigh AS, DeSantes K, Hu D, Pabst H, Horn B, Li L, Cowan MJ

Tolerance induction post in utero stem cell transplantation.

Ernst Schering Research Foundation workshop

Cowan MJ, Chou SH, Tarantal AF

An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease.

Bone marrow transplantation

Bolinger AM, Zangwill AB, Slattery JT, Glidden D, DeSantes K, Heyn L, Risler LJ, Bostrom B, Cowan MJ

Autoimmune hemolytic anemia in patients with SCID after T cell-depleted BM and PBSC transplantation.

Bone marrow transplantation

Horn B, Viele M, Mentzer W, Mogck N, DeSantes K, Cowan M

The gene for severe combined immunodeficiency disease in Athabascan-speaking Native Americans is located on chromosome 10p.

American journal of human genetics

Li L, Drayna D, Hu D, Hayward A, Gahagan S, Pabst H, Cowan MJ

Psychosocial consequences of bone marrow transplantation in donor and nondonor siblings.

Journal of developmental and behavioral pediatrics : JDBP

Packman WL, Crittenden MR, Schaeffer E, Bongar B, Fischer JB, Cowan MJ

In utero hematopoietic stem cell transplants prolong survival of postnatal kidney transplantation in monkeys.

Journal of pediatric surgery

Mychaliska GB, Rice HE, Tarantal AF, Stock PG, Capper J, Garovoy MR, Olson JL, Cowan MJ, Harrison MR

Bone marrow transplantation for inherited diseases.

Current opinion in oncology

O'Marcaigh AS, Cowan MJ

Cognitive and adaptive behavior 1 and 3 years following bone marrow transplantation.

Bone marrow transplantation

Kramer JH, Crittenden MR, DeSantes K, Cowan MJ

In utero allogeneic hematopoietic stem cell transplantation to induce tolerance.

Fetal diagnosis and therapy

Hajdu K, Tanigawara S, McLean LK, Cowan MJ, Golbus MS

Haploidentical bone marrow transplants for two patients with reticular dysgenesis.

Bone marrow transplantation

De Santes KB, Lai SS, Cowan MJ

Long-term engraftment following in utero T cell-depleted parental marrow transplantation into fetal rhesus monkeys.

Bone marrow transplantation

Cowan MJ, Tarantal AF, Capper J, Harrison M, Garovoy M

Severe combined immunodeficiency with absence of peripheral blood CD8+ T cells due to ZAP-70 deficiency.

Cellular immunology

Elder ME, Hope TJ, Parslow TG, Umetsu DT, Wara DW, Cowan MJ

Anti-tetanus toxoid antibody production after mismatched T cell-depleted bone marrow transplantation.

Journal of clinical immunology

Benkerrou M, Wara DW, Elder M, Dror Y, Merino A, Colombe BW, Garovoy M, Cowan MJ

In utero hematopoietic stem cell transplants for inherited diseases.

The American journal of pediatric hematology/oncology

Cowan MJ, Golbus M

Prenatal diagnosis of Chediak-Higashi syndrome.

Prenatal diagnosis

Diukman R, Tanigawara S, Cowan MJ, Golbus MS

Microgranulomatous aspergillosis after shoveling wood chips: report of a fatal outcome in a patient with chronic granulomatous disease.

American journal of industrial medicine

Conrad DJ, Warnock M, Blanc P, Cowan M, Golden JA

Hepatitis C virus infection in infants whose mothers took street drugs intravenously.

The Journal of pediatrics

Weintrub PS, Veereman-Wauters G, Cowan MJ, Thaler MM

Use of polymerase chain reaction for the early detection of HIV infection in the infants of HIV-seropositive women.

AIDS (London, England)

Weintrub PS, Ulrich PP, Edwards JR, Boucher F, Levy JA, Cowan MJ, Vyas GN

Total body irradiation and bone marrow transplantation for immunodeficiency disorders in young children.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Halberg FE, Wara WM, Weaver KE, Wara DW, Ablin AR, Matthay KK, Mentzer WC, O'Leary MC, Cowan MJ

Interleukin 2 responsive lymphocytes in patients with adenosine deaminase deficiency.

Clinical immunology and immunopathology

Cowan MJ, Smith W, Ammann AJ

Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7.

The Journal of clinical investigation

Shannon KM, Turhan AG, Chang SS, Bowcock AM, Rogers PC, Carroll WL, Cowan MJ, Glader BE, Eaves CJ, Eaves AC

Developmental decline in infants born to HIV-infected intravenous drug-using mothers.

NIDA research monograph

Kletter R, Jeremy RJ, Rumsey C, Weintrub P, Cowan M

Pediatric AIDS.

Immunology series

Cowan MJ, Ammann AJ

Maternally transmitted HIV infection in children.

AIDS (London, England)

Cowan MJ, Walker C, Culver K, Weintrub PS, Wara DW, Levy JA

Human immuno-deficiency virus (HIV) infection in seronegative children of HIV infected mothers

AIDS

Cowan, M.J., Walker, C., Culver, K., Wara, D., Weintrub, P.S., & Levy, J

Risk of AIDS for recipients of blood components from donors who subsequently developed AIDS.

Blood

Perkins HA, Samson S, Garner J, Echenberg D, Allen JR, Cowan M, Levy JA

Lymphocyte abnormalities in infants born to drug-abusing mothers.

The Journal of pediatrics

Culver KW, Ammann AJ, Partridge JC, Wong DF, Wara DW, Cowan MJ

Haploidentical bone marrow transplantation using soybean agglutinin-processed, T-depleted marrow.

Transplantation proceedings

Matthay K, Wara DW, Ablin AJ, Cowan MJ

Lymphocyte reconstitution in children receiving soybean agglutinin T-depleted bone marrow transplants.

Transplantation proceedings

Cowan MJ, McHugh T, Smith W, Wara D, Matthay K, Ablin A, Casavant C, Stites D

Pediatric Bone Marrow Transplantation: Intensive Care Management

Journal of Intensive Care

Shannon, K., Cowan, M.J., & Matthay, K.

Probable autoimmune thyroid disease and combined immunodeficiency disease.

American journal of diseases of children (1960)

Geffner ME, Stiehm ER, Stephure D, Cowan MJ

Elevated erythrocyte adenosine deaminase activity in patients with acquired immunodeficiency syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Cowan MJ, Brady RO, Widder KJ

A 90-day vapor inhalation toxicity study of decalin.

Fundamental and applied toxicology : official journal of the Society of Toxicology

Gaworski CL, Haun CC, MacEwen JD, Vernot EH, Bruner RH, Amster RL, Cowan MJ

Behçet syndrome.

The Journal of pediatrics

Ammann AJ, Johnson A, Fyfe GA, Leonards R, Wara DW, Cowan MJ

Comparison of high-dose and low-dose intravenous immunoglobulin therapy in patients with primary immunodeficiency diseases.

The American journal of medicine

Ochs HD, Fischer SH, Wedgwood RJ, Wara DW, Cowan MJ, Ammann AJ, Saxon A, Budinger MD, Allred RU, Rousell RH

Maternal transmission of acquired immune deficiency syndrome.

Pediatrics

Cowan MJ, Hellmann D, Chudwin D, Wara DW, Chang RS, Ammann AJ

Susceptibility to infections in patients lacking a T lymphocyte surface glycoprotein

Clin Immunol Immunopathology

Parkman, R., O'Donnell, R.E., Cairns, L., Rappeport, J.M., Cowan, M.J., Ammann, A.J., Kenney, D., Potter, N., & Rosen, F.S.

Thymosin Fraction 5 treatment of patients with cellular immunodeficiency disorders

Thymic Hormones and Lymphokines

Wara, D.W., Cowan, M.J., & Ammann, A.J.

Immunologic abnormalities in patients with hemophilia A.

The Journal of pediatrics

Weintrub PS, Koerper MA, Addiego JE, Drew WL, Lennette ET, Miner R, Cowan MJ, Ammann AJ

Significance of a positive antinuclear antibody test in a pediatric population.

American journal of diseases of children (1960)

Chudwin DS, Ammann AJ, Cowan MJ, Wara DW

Chronic active Epstein-Barr virus infections in two immunodeficient patients.

The Journal of pediatrics

Hellmann D, Cowan MJ, Ammann AJ, Wara DW, Chudwin D, Chang RS

Response of agranulocytosis to prolonged antithymocyte globulin therapy.

The Journal of pediatrics

Chudwin DS, Cowan MJ, Greenberg PL, Wara DW, Ammann AJ

Alopecia and periorificial dermatitis in biotin-responsive multiple carboxylase deficiency.

Journal of the American Academy of Dermatology

Williams ML, Packman S, Cowan MJ

Acquired immune dysfunction in homosexual men: immunologic profiles.

Clinical immunology and immunopathology

Ammann AJ, Abrams D, Conant M, Chudwin D, Cowan M, Volberding P, Lewis B, Casavant C

Acquired immunodeficiency in an infant: possible transmission by means of blood products.

Lancet (London, England)

Ammann AJ, Cowan MJ, Wara DW, Weintrub P, Dritz S, Goldman H, Perkins HA

Dipyridamole and intravenous deoxycytidine therapy in a patient with adenosine deaminase deficiency.

Birth defects original article series

Ammann AJ, Cowan MJ, Martin DW, Wara DW

Patients with abnormal proportions of T-lymphocyte subsets have reduced in vitro cellular immunity.

Clinical immunology and immunopathology

Chudwin DS, Cowan MJ, Wara DW, Ammann AJ

Unexplained immunodeficiency and opportunistic infections in infants--New York, New Jersey, California.

MMWR. Morbidity and mortality weekly report

Centers for Disease Control (CDC)

Possible transfusion-associated acquired immune deficiency syndrome (AIDS) - California.

MMWR. Morbidity and mortality weekly report

Centers for Disease Control (CDC)

Aspergillus pneumonia in chronic granulomatous disease: recurrence and long-term outcome.

Acta paediatrica Scandinavica

Chudwin DS, Wara DW, Cowan MJ, Ammann AJ

The DiGeorge syndrome and the fetal alcohol syndrome.

American journal of diseases of children (1960)

Ammann AJ, Wara DW, Cowan MJ, Barrett DJ, Stiehm ER

Posttransfusion syndrome. Rash, eosinophilia, and thrombocytopenia following intrauterine and exchange transfusions.

American journal of diseases of children (1960)

Chudwin DS, Ammann AJ, Wara DW, Cowan MJ, Phibbs RH

Prenatal treatment of biotin responsive multiple carboxylase deficiency.

Lancet (London, England)

Packman S, Cowan MJ, Golbus MS, Caswell NM, Sweetman L, Burri BJ, Nyhan WL, Baker H

Purine salvage pathway enzyme activities in human T-, B-, and null lymphocyte populations.

Cellular immunology

Cowan MJ, Fraga M, Andrew J, Laméris-Martin N, Ammann AJ

Biotin-responsive multiple carboxylase deficiency of infantile onset.

The Journal of pediatrics

Packman S, Sweetman L, Yoshino M, Baker H, Cowan M

Clinical and immunologic spectrum of the DiGeorge syndrome.

Journal of clinical & laboratory immunology

Barrett DJ, Ammann AJ, Wara DW, Cowan MJ, Fisher TJ, Stiehm ER

Lung involvement in progressive vaccinia.

The Western journal of medicine

Chudwin DS, Cowan MJ, Wara DW, Johnson AC

Aging and immunologic function: In vitro effects of thymosin on cellular immunity

Mech Aqinq and Development

Cowan, M.J., Fujiwara, P., & Ammann, A.J.

Immunology

AAP

Ammann, A.J., Cowan, M.J., & Wara, D.W.

Sjogren's syndrome in the pediatric age group

J Pediat.

Chudwin, D.S., Daniels, T.E., Wara, D.W., Ammann, A.J., Barrett, D.J., Witcher, J.P., & Cowan, M.J.

Intermittent ataxia and immunodeficiency with multiple carboxylase deficiencies: a biotin-responsive disorder.

Annals of neurology

Sander JE, Malamud N, Cowan MJ, Packman S, Amman AJ, Wara DW

Collagen concentration and rates of synthesis in idiopathic pulmonary fibrosis.

The American review of respiratory disease

Fulmer JD, Bienkowski RS, Cowan MJ, Breul SD, Bradley KM, Ferrans VJ, Roberts WC, Crystal RG

Thymosin therapy in the DiGeorge syndrome.

The Journal of pediatrics

Barrett DJ, Wara DW, Ammann AJ, Cowan MJ

Multiple biotin-dependent carboxylase deficiencies associated with defects in T-cell and B-cell immunity.

Lancet (London, England)

Cowan MJ, Wara DW, Packman S, Ammann AJ, Yoshino M, Sweetman L, Nyhan W

Pneumococcal polysaccharide immunization in infants and children.

Pediatrics

Cowan MJ, Ammann AJ, Wara DW, Howie VM, Schultz L, Doyle N, Kaplan M

Degradation of newly synthesized collagen.

The Journal of biological chemistry

Bienkowski RS, Cowan MJ, McDonald JA, Crystal RG

Alveolar multiplication in the contralateral lung after unilateral pneumonectomy in the rabbit.

The American review of respiratory disease

Langston C, Sachdeva P, Cowan MJ, Haines J, Crystal RG, Thurlbeck WM

Biochemical approaches to the investigation of fibrotic lung disease.

Chest

Hance AJ, Horwitz AL, Cowan MJ, Elson NA, Collins JF, Bienkowski RS, Bradley KH, McConnell-Breul S, Wagner WM, Crystal RG

Lung growth after unilateral pneumonectomy: quantitation of collagen synthesis and content.

The American review of respiratory disease

Cowan MJ, Crystal RG

Collagen in the lung: development of a technology applicable to human lung disease.

Chest

Crystal RG, Bradley KH, McConnell-Breu SD, Collins JF, Hanca AJ, Cowan MJ