Arturo Alvarez-Buylla

Neural stem cell relay from B1 to B2 cells in the adult mouse ventricular-subventricular zone.

Cell reports

Cebrian-Silla A, Nascimento MA, Mancia W, Gonzalez-Granero S, Romero-Rodriguez R, Obernier K, Steffen DM, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A

Integration of Transplanted Interneurons Over a New Period of Ocular Dominance Plasticity in Adult Visual Cortex.

bioRxiv : the preprint server for biology

Rakela B, Sun J, Marchetta P, Alvarez-Buylla A, Hasenstaub A, Stryker M

Molecular and cellular dynamics of the developing human neocortex.

Nature

Wang L, Wang C, Moriano JA, Chen S, Zuo G, Cebrián-Silla A, Zhang S, Mukhtar T, Wang S, Song M, de Oliveira LG, Bi Q, Augustin JJ, Ge X, Paredes MF, Huang EJ, Alvarez-Buylla A, Duan X, Li J, Kriegstein AR

Molecular and cellular dynamics of the developing human neocortex at single-cell resolution.

bioRxiv : the preprint server for biology

Wang L, Wang C, Moriano JA, Chen S, Zuo G, Cebrián-Silla A, Zhang S, Mukhtar T, Wang S, Song M, de Oliveira LG, Bi Q, Augustin JJ, Ge X, Paredes MF, Huang EJ, Alvarez-Buylla A, Duan X, Li J, Kriegstein AR

Neural Stem Cell Relay from B1 to B2 cells in the adult mouse Ventricular-Subventricular Zone.

bioRxiv : the preprint server for biology

Cebrian-Silla A, Assis Nascimento M, Mancia W, Gonzalez-Granero S, Romero-Rodriguez R, Obernier K, Steffen DM, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A

The clustered gamma protocadherin PcdhγC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex.

Proceedings of the National Academy of Sciences of the United States of America

Leon WRM, Steffen DM, Dale-Huang FR, Rakela B, Breevoort A, Romero-Rodriguez R, Hasenstaub AR, Stryker MP, Weiner JA, Alvarez-Buylla A

Protracted neuronal recruitment in the temporal lobe of young children.

Nature

Nascimento MA, Biagiotti S, Herranz-Pérez V, Santiago S, Bueno R, Ye CJ, Abel TJ, Zhang Z, Rubio-Moll JS, Kriegstein AR, Yang Z, Garcia-Verdugo JM, Huang EJ, Alvarez-Buylla A, Sorrells SF

Developmental origin and local signals cooperate to determine septal astrocyte identity.

bioRxiv : the preprint server for biology

Xie Y, Reid CM, Granados AA, Garcia MT, Dale-Huang F, Hanson SM, Mancia W, Liu J, Adam M, Mosto O, Pisco AO, Alvarez-Buylla A, Harwell CC

Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy.

Cell stem cell

Bershteyn M, Bröer S, Parekh M, Maury Y, Havlicek S, Kriks S, Fuentealba L, Lee S, Zhou R, Subramanyam G, Sezan M, Sevilla ES, Blankenberger W, Spatazza J, Zhou L, Nethercott H, Traver D, Hampel P, Kim H, Watson M, Salter N, Nesterova A, Au W, Kriegstein A, Alvarez-Buylla A, Rubenstein J, Banik G, Bulfone A, Priest C, Nicholas CR

A cross-species proteomic map reveals neoteny of human synapse development.

Nature

Wang L, Pang K, Zhou L, Cebrián-Silla A, González-Granero S, Wang S, Bi Q, White ML, Ho B, Li J, Li T, Perez Y, Huang EJ, Winkler EA, Paredes MF, Kovner R, Sestan N, Pollen AA, Liu P, Li J, Piao X, García-Verdugo JM, Alvarez-Buylla A, Liu Z, Kriegstein AR

Prdm16 and Vcam1 regulate the postnatal disappearance of embryonic radial glia and the ending of cortical neurogenesis.

bioRxiv : the preprint server for biology

Li J, Godoy MI, Zhang AJ, Diamante G, Ahn IS, Cebrian-Silla A, Alvarez-Buylla A, Yang X, Novitch BG, Zhang Y

The Clustered Gamma Protocadherin Pcdh?c4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex.

bioRxiv : the preprint server for biology

Mancia Leon WR, Steffen DM, Dale-Huang F, Rakela B, Breevoort A, Romero-Rodriguez R, Hasenstaub AR, Stryker MP, Weiner JA, Alvarez-Buylla A

Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain.

Cell

Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ

Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis".

Science (New York, N.Y.)

Alvarez-Buylla A, Cebrian-Silla A, Sorrells SF, Nascimento MA, Paredes MF, Garcia-Verdugo JM, Yang Z, Huang EJ

Nests of dividing neuroblasts sustain interneuron production for the developing human brain.

Science (New York, N.Y.)

Paredes MF, Mora C, Flores-Ramirez Q, Cebrian-Silla A, Del Dosso A, Larimer P, Chen J, Kang G, Gonzalez Granero S, Garcia E, Chu J, Delgado R, Cotter JA, Tang V, Spatazza J, Obernier K, Ferrer Lozano J, Vento M, Scott J, Studholme C, Nowakowski TJ, Kriegstein AR, Oldham MC, Hasenstaub A, Garcia-Verdugo JM, Alvarez-Buylla A, Huang EJ

Individual human cortical progenitors can produce excitatory and inhibitory neurons.

Nature

Delgado RN, Allen DE, Keefe MG, Mancia Leon WR, Ziffra RS, Crouch EE, Alvarez-Buylla A, Nowakowski TJ

Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K, Knox A, Connolly A, Huang EJ, Garcia-Verdugo JM, Oldham MC, Yang Z, Alvarez-Buylla A

Origins and Proliferative States of Human Oligodendrocyte Precursor Cells.

Cell

Huang W, Bhaduri A, Velmeshev D, Wang S, Wang L, Rottkamp CA, Alvarez-Buylla A, Rowitch DH, Kriegstein AR

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

eLife

Mancia Leon WR, Spatazza J, Rakela B, Chatterjee A, Pande V, Maniatis T, Hasenstaub AR, Stryker MP, Alvarez-Buylla A

Maintenance of neural stem cell positional identity by mixed-lineage leukemia 1.

Science (New York, N.Y.)

Delgado RN, Mansky B, Ahanger SH, Lu C, Andersen RE, Dou Y, Alvarez-Buylla A, Lim DA

Transplanted Cells Are Essential for the Induction But Not the Expression of Cortical Plasticity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Hoseini MS, Rakela B, Flores-Ramirez Q, Hasenstaub AR, Alvarez-Buylla A, Stryker MP

Immature excitatory neurons develop during adolescence in the human amygdala.

Nature communications

Sorrells SF, Paredes MF, Velmeshev D, Herranz-P?rez V, Sandoval K, Mayer S, Chang EF, Insausti R, Kriegstein AR, Rubenstein JL, Manuel Garcia-Verdugo J, Huang EJ, Alvarez-Buylla A

Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor.

Cell reports

Redmond SA, Figueres-O?ate M, Obernier K, Nascimento MA, Parraguez JI, L?pez-Mascaraque L, Fuentealba LC, Alvarez-Buylla A

Neural stem cells: origin, heterogeneity and regulation in the adult mammalian brain.

Development (Cambridge, England)

Obernier K, Alvarez-Buylla A

Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex.

Neuron

Mayer S, Chen J, Velmeshev D, Mayer A, Eze UC, Bhaduri A, Cunha CE, Jung D, Arjun A, Li E, Alvarado B, Wang S, Lovegren N, Gonzales ML, Szpankowski L, Leyrat A, West JAA, Panagiotakos G, Alvarez-Buylla A, Paredes MF, Nowakowski TJ, Pollen AA, Kriegstein AR

Vesicular GABA Transporter Is Necessary for Transplant-Induced Critical Period Plasticity in Mouse Visual Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Priya R, Rakela B, Kaneko M, Spatazza J, Larimer P, Hoseini MS, Hasenstaub AR, Alvarez-Buylla A, Stryker MP

Does Adult Neurogenesis Persist in the Human Hippocampus?

Cell stem cell

Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.

Nature cell biology

Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM

Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development.

Cerebral cortex (New York, N.Y. : 1991)

Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z

Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity.

Cerebral cortex (New York, N.Y. : 1991)

Raju CS, Spatazza J, Stanco A, Larimer P, Sorrells SF, Kelley KW, Nicholas CR, Paredes MF, Lui JH, Hasenstaub AR, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL, Oldham MC

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.

Cancer cell

Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, Ghosh M, Tirosh I, Huillard E, Alvarez-Buylla A, Oldham MC, Persson AI, Weiss WA, Batchelor TT, Stemmer-Rachamimov A, Suvà ML, Phillips JJ, Aghi MK, Mehta S, Jain RK, Rowitch DH

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.

Nature

Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A

Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism.

Cell reports

Priya R, Paredes MF, Karayannis T, Yusuf N, Liu X, Jaglin X, Graef I, Alvarez-Buylla A, Fishell G

Adult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation.

Cell stem cell

Obernier K, Cebrian-Silla A, Thomson M, Parraguez JI, Anderson R, Guinto C, Rodas Rodriguez J, Garcia-Verdugo JM, Alvarez-Buylla A

Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells.

Stem cell reports

Cebri?n-Silla A, Alfaro-Cervell? C, Herranz-P?rez V, Kaneko N, Park DH, Sawamoto K, Alvarez-Buylla A, Lim DA, Garc?a-Verdugo JM

Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier.

Cell reports

Yulyaningsih E, Rudenko IA, Valdearcos M, Dahl?n E, Vagena E, Chan A, Alvarez-Buylla A, Vaisse C, Koliwad SK, Xu AW

Development and long-term integration of MGE-lineage cortical interneurons in the heterochronic environment.

Journal of neurophysiology

Larimer P, Spatazza J, Stryker MP, Alvarez-Buylla A, Hasenstaub AR

Transplantation of GABAergic interneurons for cell-based therapy.

Progress in brain research

Spatazza J, Mancia Leon WR, Alvarez-Buylla A

Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories.

Nature communications

Mirzadeh Z, Kusne Y, Duran-Moreno M, Cabrales E, Gil-Perotin S, Ortiz C, Chen B, Garcia-Verdugo JM, Sanai N, Alvarez-Buylla A

Extensive migration of young neurons into the infant human frontal lobe.

Science (New York, N.Y.)

Paredes MF, James D, Gil-Perotin S, Kim H, Cotter JA, Ng C, Sandoval K, Rowitch DH, Xu D, McQuillen PS, Garcia-Verdugo JM, Huang EJ, Alvarez-Buylla A

Caudal Ganglionic Eminence Precursor Transplants Disperse and Integrate as Lineage-Specific Interneurons but Do Not Induce Cortical Plasticity.

Cell reports

Larimer P, Spatazza J, Espinosa JS, Tang Y, Kaneko M, Hasenstaub AR, Stryker MP, Alvarez-Buylla A

Planar Organization of Multiciliated Ependymal (E1) Cells in the Brain Ventricular Epithelium.

Trends in neurosciences

Ohata S, Alvarez-Buylla A

Identification of proliferative progenitors associated with prominent postnatal growth of the pons.

Nature communications

Lindquist RA, Guinto CD, Rodas-Rodriguez JL, Fuentealba LC, Tate MC, Rowitch DH, Alvarez-Buylla A

The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis.

Cold Spring Harbor perspectives in biology

Lim DA, Alvarez-Buylla A

Brain size and limits to adult neurogenesis.

The Journal of comparative neurology

Paredes MF, Sorrells SF, Garcia-Verdugo JM, Alvarez-Buylla A

A Dorsal SHH-Dependent Domain in the V-SVZ Produces Large Numbers of Oligodendroglial Lineage Cells in the Postnatal Brain.

Stem cell reports

Tong CK, Fuentealba LC, Shah JK, Lindquist RA, Ihrie RA, Guinto CD, Rodas-Rodriguez JL, Alvarez-Buylla A

Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons.

Neuron

Harwell CC, Fuentealba LC, Gonzalez-Cerrillo A, Parker PR, Gertz CC, Mazzola E, Garcia MT, Alvarez-Buylla A, Cepko CL, Kriegstein AR

Embryonic Origin of Postnatal Neural Stem Cells.

Cell

Fuentealba LC, Rompani SB, Parraguez JI, Obernier K, Romero R, Cepko CL, Alvarez-Buylla A

Viral-mediated Labeling and Transplantation of Medial Ganglionic Eminence (MGE) Cells for In Vivo Studies.

Journal of visualized experiments : JoVE

Vogt D, Wu PR, Sorrells SF, Arnold C, Alvarez-Buylla A, Rubenstein JL

A cortical disinhibitory circuit for enhancing adult plasticity.

eLife

Fu Y, Kaneko M, Tang Y, Alvarez-Buylla A, Stryker MP

Cortical plasticity induced by transplantation of embryonic somatostatin or parvalbumin interneurons.

Proceedings of the National Academy of Sciences of the United States of America

Tang Y, Stryker MP, Alvarez-Buylla A, Espinosa JS

Postnatal growth of the human pons: a morphometric and immunohistochemical analysis.

The Journal of comparative neurology

Tate MC, Lindquist RA, Nguyen T, Sanai N, Barkovich AJ, Huang EJ, Rowitch DH, Alvarez-Buylla A

Astrocyte development and heterogeneity.

Cold Spring Harbor perspectives in biology

Bayraktar OA, Fuentealba LC, Alvarez-Buylla A, Rowitch DH

Adult neural stem cells stake their ground.

Trends in neurosciences

Lim DA, Alvarez-Buylla A

Yoshiki Sasai (1962-2014).

Nature

Alvarez-Buylla A

Primary cilia are required in a unique subpopulation of neural progenitors.

Proceedings of the National Academy of Sciences of the United States of America

Tong CK, Han YG, Shah JK, Obernier K, Guinto CD, Alvarez-Buylla A

Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus.

Neuron

Ohata S, Nakatani J, Herranz-P?rez V, Cheng J, Belinson H, Inubushi T, Snider WD, Garc?a-Verdugo JM, Wynshaw-Boris A, Alvarez-Buylla A

Inhibitory interneuron progenitor transplantation restores normal learning and memory in ApoE4 knock-in mice without or with A� accumulation.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Tong LM, Djukic B, Arnold C, Gillespie AK, Yoon SY, Wang MM, Zhang O, Knoferle J, Rubenstein JL, Alvarez-Buylla A, Huang Y

Restricted nature of adult neural stem cells: re-evaluation of their potential for brain repair.

Frontiers in neuroscience

Obernier K, Tong CK, Alvarez-Buylla A

The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human.

The Journal of comparative neurology

Alfaro-Cervello C, Cebrian-Silla A, Soriano-Navarro M, Garcia-Tarraga P, Mat?as-Guiu J, Gomez-Pinedo U, Molina Aguilar P, Alvarez-Buylla A, Luquin MR, Garcia-Verdugo JM

Distinct and separable roles for EZH2 in neurogenic astroglia.

eLife

Hwang WW, Salinas RD, Siu JJ, Kelley KW, Delgado RN, Paredes MF, Alvarez-Buylla A, Oldham MC, Lim DA

Interneurons from embryonic development to cell-based therapy.

Science (New York, N.Y.)

Southwell DG, Nicholas CR, Basbaum AI, Stryker MP, Kriegstein AR, Rubenstein JL, Alvarez-Buylla A

Axonal control of the adult neural stem cell niche.

Cell stem cell

Tong CK, Chen J, Cebri?n-Silla A, Mirzadeh Z, Obernier K, Guinto CD, Tecott LH, Garc?a-Verdugo JM, Kriegstein A, Alvarez-Buylla A

SnapShot: adult neurogenesis in the V-SVZ.

Neuron

Tong CK, Alvarez-Buylla A

Axons take a dive: Specialized contacts of serotonergic axons with cells in the walls of the lateral ventricles in mice and humans.

Neurogenesis (Austin, Tex.)

Tong CK, Cebri?n-Silla A, Paredes MF, Huang EJ, Garc?a-Verdugo JM, Alvarez-Buylla A

Molecular diversity subdivides the adult forebrain neural stem cell population.

Stem cells (Dayton, Ohio)

Giachino C, Basak O, Lugert S, Knuckles P, Obernier K, Fiorelli R, Frank S, Raineteau O, Alvarez-Buylla A, Taylor V

Adult neural stem cells in distinct microdomains generate previously unknown interneuron types.

Nature neuroscience

Merkle FT, Fuentealba LC, Sanders TA, Magno L, Kessaris N, Alvarez-Buylla A

Neocortical integration of transplanted GABA progenitor cells from wild type and GABA(B) receptor knockout mouse donors.

Neuroscience letters

Sebe JY, Looke-Stewart E, Dinday MT, Alvarez-Buylla A, Baraban SC

Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences.

Nature neuroscience

Hansen DV, Lui JH, Flandin P, Yoshikawa K, Rubenstein JL, Alvarez-Buylla A, Kriegstein AR

Myb promotes centriole amplification and later steps of the multiciliogenesis program.

Development (Cambridge, England)

Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA

Molecular Characteristics in MRI-Classified Group 1 Glioblastoma Multiforme.

Frontiers in oncology

Haskins WE, Zablotsky BL, Foret MR, Ihrie RA, Alvarez-Buylla A, Eisenman RN, Berger MS, Lin CH

Lineage progression from stem cells to new neurons in the adult brain ventricular-subventricular zone.

Cell cycle (Georgetown, Tex.)

Ponti G, Obernier K, Alvarez-Buylla A

GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior.

Nature neuroscience

Hunt RF, Girskis KM, Rubenstein JL, Alvarez-Buylla A, Baraban SC

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

Cell stem cell

Nicholas CR, Chen J, Tang Y, Southwell DG, Chalmers N, Vogt D, Arnold CM, Chen YJ, Stanley EG, Elefanty AG, Sasai Y, Alvarez-Buylla A, Rubenstein JL, Kriegstein AR

Use of "MGE enhancers" for labeling and selection of embryonic stem cell-derived medial ganglionic eminence (MGE) progenitors and neurons.

PloS one

Chen YJ, Vogt D, Wang Y, Visel A, Silberberg SN, Nicholas CR, Danjo T, Pollack JL, Pennacchio LA, Anderson S, Sasai Y, Baraban SC, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL

Cell cycle and lineage progression of neural progenitors in the ventricular-subventricular zones of adult mice.

Proceedings of the National Academy of Sciences of the United States of America

Ponti G, Obernier K, Guinto C, Jose L, Bonfanti L, Alvarez-Buylla A

Stem cells in the land of the rising sun: ISSCR 2012.

Cell stem cell

Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR

Biciliated ependymal cell proliferation contributes to spinal cord growth.

The Journal of comparative neurology

Alfaro-Cervello C, Soriano-Navarro M, Mirzadeh Z, Alvarez-Buylla A, Garcia-Verdugo JM

Intrinsically determined cell death of developing cortical interneurons.

Nature

Southwell DG, Paredes MF, Galvao RP, Jones DL, Froemke RC, Sebe JY, Alfaro-Cervello C, Tang Y, Garcia-Verdugo JM, Rubenstein JL, Baraban SC, Alvarez-Buylla A

Sox1 marks an activated neural stem/progenitor cell in the hippocampus.

Development (Cambridge, England)

Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R

Regional astrocyte allocation regulates CNS synaptogenesis and repair.

Science (New York, N.Y.)

Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH

Adult neural stem cells bridge their niche.

Cell stem cell

Fuentealba LC, Obernier K, Alvarez-Buylla A

Forebrain GABAergic neuron precursors integrate into adult spinal cord and reduce injury-induced neuropathic pain.

Neuron

Br?z JM, Sharif-Naeini R, Vogt D, Kriegstein A, Alvarez-Buylla A, Rubenstein JL, Basbaum AI

Distinct patterns of human medulloblastoma dissemination in the developing chick embryo nervous system.

Clinical & experimental metastasis

Cage TA, Louie JD, Liu SR, Alvarez-Buylla A, Gupta N, Hyer J

Corridors of migrating neurons in the human brain and their decline during infancy.

Nature

Sanai N, Nguyen T, Ihrie RA, Mirzadeh Z, Tsai HH, Wong M, Gupta N, Berger MS, Huang E, Garcia-Verdugo JM, Rowitch DH, Alvarez-Buylla A

Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.

Neuron

Ihrie RA, Shah JK, Harwell CC, Levine JH, Guinto CD, Lezameta M, Kriegstein AR, Alvarez-Buylla A

Lake-front property: a unique germinal niche by the lateral ventricles of the adult brain.

Neuron

Ihrie RA, Alvarez-Buylla A

Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain.

The Journal of comparative neurology

Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, Okano H

Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor.

Brain research reviews

Gonzalez-Perez O, Alvarez-Buylla A

New neurons clear the path of astrocytic processes for their rapid migration in the adult brain.

Neuron

Kaneko N, Mar?n O, Koike M, Hirota Y, Uchiyama Y, Wu JY, Lu Q, Tessier-Lavigne M, Alvarez-Buylla A, Okano H, Rubenstein JL, Sawamoto K

The subventricular zone en-face: wholemount staining and ependymal flow.

Journal of visualized experiments : JoVE

Mirzadeh Z, Doetsch F, Sawamoto K, Wichterle H, Alvarez-Buylla A

Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats.

Cell stem cell

Mart?nez-Cerde?o V, Noctor SC, Espinosa A, Ariza J, Parker P, Orasji S, Daadi MM, Bankiewicz K, Alvarez-Buylla A, Kriegstein AR

Cortical plasticity induced by inhibitory neuron transplantation.

Science (New York, N.Y.)

Southwell DG, Froemke RC, Alvarez-Buylla A, Stryker MP, Gandhi SP

Cilia organize ependymal planar polarity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Mirzadeh Z, Han YG, Soriano-Navarro M, García-Verdugo JM, Alvarez-Buylla A

Role of primary cilia in brain development and cancer.

Current opinion in neurobiology

Han YG, Alvarez-Buylla A

Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.

Cell stem cell

Lo B, Parham L, Alvarez-Buylla A, Cedars M, Conklin B, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Wagner R

Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes.

The EMBO journal

Jacques TS, Swales A, Brzozowski MJ, Henriquez NV, Linehan JM, Mirzadeh Z, O' Malley C, Naumann H, Alvarez-Buylla A, Brandner S

Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice.

Proceedings of the National Academy of Sciences of the United States of America

Baraban SC, Southwell DG, Estrada RC, Jones DL, Sebe JY, Alfaro-Cervello C, García-Verdugo JM, Rubenstein JL, Alvarez-Buylla A

Dual and opposing roles of primary cilia in medulloblastoma development.

Nature medicine

Han YG, Kim HJ, Dlugosz AA, Ellison DW, Gilbertson RJ, Alvarez-Buylla A

Epidermal growth factor induces the progeny of subventricular zone type B cells to migrate and differentiate into oligodendrocytes.

Stem cells (Dayton, Ohio)

Gonzalez-Perez O, Romero-Rodriguez R, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla A

Radiation damage increases Purkinje neuron heterokaryons in neonatal cerebellum.

Annals of neurology

Espejel S, Romero R, Alvarez-Buylla A

Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells.

Nature

Lim DA, Huang YC, Swigut T, Mirick AL, Garcia-Verdugo JM, Wysocka J, Ernst P, Alvarez-Buylla A

Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.

Cancer cell

Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF

Identification and characterization of neural progenitor cells in the adult mammalian brain.

Advances in anatomy, embryology, and cell biology

Gil-Perotín S, Alvarez-Buylla A, García-Verdugo JM

The glial nature of embryonic and adult neural stem cells.

Annual review of neuroscience

Kriegstein A, Alvarez-Buylla A

Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Galvão RP, Garcia-Verdugo JM, Alvarez-Buylla A

The heterogeneity of adult neural stem cells and the emerging complexity of their niche.

Cold Spring Harbor symposia on quantitative biology

Alvarez-Buylla A, Kohwi M, Nguyen TM, Merkle FT

Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain.

Cell stem cell

Mirzadeh Z, Merkle FT, Soriano-Navarro M, Garcia-Verdugo JM, Alvarez-Buylla A

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

Cancer cell

Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL

Origin and function of olfactory bulb interneuron diversity.

Trends in neurosciences

Lledo PM, Merkle FT, Alvarez-Buylla A

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.

BMC medicine

Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG

Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool.

Developmental biology

Spassky N, Han YG, Aguilar A, Strehl L, Besse L, Laclef C, Ros MR, Garcia-Verdugo JM, Alvarez-Buylla A

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells.

Nature neuroscience

Han YG, Spassky N, Romaguera-Ros M, Garcia-Verdugo JM, Aguilar A, Schneider-Maunoury S, Alvarez-Buylla A

Characterization of adult neural stem cells and their relation to brain tumors.

Cells, tissues, organs

Jackson EL, Alvarez-Buylla A

Developing cell transplantation for temporal lobe epilepsy.

Neurosurgical focus

Richardson RM, Barbaro NM, Alvarez-Buylla A, Baraban SC

Comment on "Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension".

Science (New York, N.Y.)

Sanai N, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A

Cells in the astroglial lineage are neural stem cells.

Cell and tissue research

Ihrie RA, Alvarez-Buylla A

Beta-catenin signaling promotes proliferation of progenitor cells in the adult mouse subventricular zone.

Stem cells (Dayton, Ohio)

Adachi K, Mirzadeh Z, Sakaguchi M, Yamashita T, Nikolcheva T, Gotoh Y, Peltz G, Gong L, Kawase T, Alvarez-Buylla A, Okano H, Sawamoto K

Mosaic organization of neural stem cells in the adult brain.

Science (New York, N.Y.)

Merkle FT, Mirzadeh Z, Alvarez-Buylla A

A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Kohwi M, Petryniak MA, Long JE, Ekker M, Obata K, Yanagawa Y, Rubenstein JL, Alvarez-Buylla A

Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Long JE, Garel S, Alvarez-Dolado M, Yoshikawa K, Osumi N, Alvarez-Buylla A, Rubenstein JL

The adult neural stem cell niche: lessons for future neural cell replacement strategies.

Neurosurgery clinics of North America

Lim DA, Huang YC, Alvarez-Buylla A

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche.

Cell

Kuo CT, Mirzadeh Z, Soriano-Navarro M, Rasin M, Wang D, Shen J, Sestan N, Garcia-Verdugo J, Alvarez-Buylla A, Jan LY, Jan YN

Neural stem cells in mammalian development.

Current opinion in cell biology

Merkle FT, Alvarez-Buylla A

Origin of oligodendrocytes in the subventricular zone of the adult brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Menn B, Garcia-Verdugo JM, Yaschine C, Gonzalez-Perez O, Rowitch D, Alvarez-Buylla A

PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling.

Neuron

Jackson EL, Garcia-Verdugo JM, Gil-Perotin S, Roy M, Quinones-Hinojosa A, VandenBerg S, Alvarez-Buylla A

Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Alvarez-Dolado M, Calcagnotto ME, Karkar KM, Southwell DG, Jones-Davis DM, Estrada RC, Rubenstein JL, Alvarez-Buylla A, Baraban SC

Composition and organization of the SCZ: a large germinal layer containing neural stem cells in the adult mammalian brain.

Cerebral cortex (New York, N.Y. : 1991)

Seri B, Herrera DG, Gritti A, Ferron S, Collado L, Vescovi A, Garcia-Verdugo JM, Alvarez-Buylla A

Magnetic resonance imaging of the migration of neuronal precursors generated in the adult rodent brain.

NeuroImage

Shapiro EM, Gonzalez-Perez O, Manuel García-Verdugo J, Alvarez-Buylla A, Koretsky AP

Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells.

Developmental biology

Masahira N, Takebayashi H, Ono K, Watanabe K, Ding L, Furusho M, Ogawa Y, Nabeshima Y, Alvarez-Buylla A, Shimizu K, Ikenaka K

Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells.

The Journal of comparative neurology

Quiñones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perez O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriguez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A

New neurons follow the flow of cerebrospinal fluid in the adult brain.

Science (New York, N.Y.)

Sawamoto K, Wichterle H, Gonzalez-Perez O, Cholfin JA, Yamada M, Spassky N, Murcia NS, Garcia-Verdugo JM, Marin O, Rubenstein JL, Tessier-Lavigne M, Okano H, Alvarez-Buylla A