Claire Clelland, MD, PhD

Assistant Professor
Neurology

Claire Clelland, MD, PhD, MPhil aims to develop novel therapies for dementia and related neurodegenerative diseases. Her lab works to create new CRISPR gene editing approaches in human iPSC-derived cell types relevant to disease. They also work to build cell model systems that more faithfully replicate human disease.

Publications

Antigen specificity of clonally enriched CD8+ T cells in multiple sclerosis.

Nature immunology

Hayashi F, Mittl K, Dandekar R, Gerdts J, Hassan E, Schubert RD, Oshiro L, Loudermilk R, Greenfield A, Augusto DG, Havton G, Anumarlu S, Surapaneni A, Ramesh A, Tran E, Koshal K, Kizer K, Dreux J, Cagalingan AK, Schustek F, Flood L, Moore T, Kirkemo LL, Fisher IJ, Cooper T, Harms M, Gomez R, University of California, San Francisco MS-EPIC Team, Clelland CD, Sibener L, Cree BAC, Hauser SL, Hollenbach JA, Gee M, Wilson MR, Zamvil SS, Sabatino JJ

Efficient in vivo mammalian neuron editing using peptide-mediated CRISPR enzyme delivery.

bioRxiv : the preprint server for biology

Manohar BD, Travis M, Munjal V, Baehr CM, Rahnama LMA, Kang MH, Haddad RF, Asija K, Noel EA, Peddireddy N, Chouhan RS, Sharma R, Wyman SK, Krishnappa N, Killebrew DA, Li SH, Snow KJ, Byrne AK, Boosani CS, Otero PA, Bringas J, O'Brien AA, Rocco MT, Zimmerly MP, Gray I, Sran GK, Patel MI, Seidensticker EF, Saville E, Gaitan Y, Schmelzle AL, Subramanyam PNB, Samaranch L, Green JA, Wells KD, Ehrenberg AJ, Murray SA, Clelland CD, Murthy N, Lonser RR, Hadaczek P, Van Laar VS, Bankiewicz KS, Wilson RC

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Frost B, Rowe JB, Akinyemi RO, Abisambra JF, Ashton NJ, Brendel M, Buée L, Butler D, Carrillo MC, Chung P, Clelland CD, DeVos SL, Diaz K, Edelmayer RM, Elahi FM, Ellajosyula R, Ewen C, Fontana IC, Galas MC, Hansson O, Höglinger G, Horie K, Ibanez A, Jacobs L, Maina MB, Malpetti M, McDade E, McEwan W, Montoliu-Gaya L, Mummery CJ, Orr ME, Rohrer JD, Rommel A, Sastre C, Spires-Jones TL, Tee BL, Viney TJ, Walker JM, Wegmann S, Wildsmith K, Yadav R, Mahinrad S, Sexton C

Novel avenues of tau research.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, Matallana D, Miller BL, Onyike CU, Quiroz YT, Rexach JE, Rohrer JD, Rommel A, Sadri-Vakili G, Schindler SE, Schneider JA, Sperling RA, Teunissen CE, Weninger SC, Worley SL, Zheng H, Carrillo MC